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127 Cards in this Set

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6 Levels of Body Organization
1. Chemical:
2. Cellular:
3. Tissue:
4. Organ:
5. System:
6. Organism:
Organ:
group of tissues w/ common function
System:
group of organs w/ common function
Organism:
contains all systems in the body
Responsiveness:
ability to detect & respond to changes in internal or external environment
Metabolism:
all chemical processes in the body
Homeostasis: Process of maintaining stable internal environment in the face of…
1. changes in external environment as a result of interacting with the world
2. changes in internal environment as a result of carrying out life processes
negative feedback systems
“Opposite,” not “bad”
Reverses departure from homeostasis, bring variable back to normal
Examples of Negative Feed Back System
Blood pressure, hormone secretion, blood sugar levels, body water content, body pH levels
Slide example: you are hiking in the sun. You get Hot. Body temp rises causing your body to release a chemical causing you to sweat. Sweat evaporates on the skin and lowers your body temp.
Steps of Negative Feedback Loop
1. Normal Homeostasis distrubed
2. Receptors: Temp sensors in skin and Hypothalmus
3. Information affects the thermoregulatory center in the brain.
4. Sends commands to the Effectors causing sweat glands to secrete.
5. Normal temp restored. Homeostasis.
Physiological Terms: Positive Feedback
Less common
Promotes/accelerates departure from homeostasis (i.e., “feed-forward” response)
For specific purpose & duration
Must be controlled or can be “run-away” response
Uterine contractions
Blood clotting
Example:
1. break in blood vessel will cause bleeding
2. Dmged cells release chemicals
3. Clotting begins
4. additional chemicals released and clotting accelorates (positive feed back loop)
5. Blood clot plugs the break in the vessel wall stopping the bleeding.
Anatomical Position
1. Stand straight, head level, eyes forward, palms forward, toes straight ahead
2. “Reference” position
3. “Left,” “right” for subject, not observer
Planes of the Body
1. Frontal/Coronal- Anterior-posterior
2. Transverse- Superior-inferior
3. Sagittal- Left-right
Anatomical Landmarks:
Abdominopelvic Regions
(9)
1. Right/Left Hypoconhriac Region
2. Right/Left Lumbar Region
3. Right/Left Inguinal Region
4. Epigastric Region
5. Umbilical Region
6. Hypogastric Region
Directional Terms:
Anterior
The Front Surface
The navel is on the Anterior surface of the trunk
Directional Terms:
Ventral
The belly side. (Equivalent to the Anterior)
The navel is on the VENTRAL surface of the trunk
Directional Terms:
Posterior or Dorsal
The back surface
the shoulder blade is located posterior to the ribcage
Directional Terms:
Superior
Above, at a higher level
The cranial border to the pelvis is superior to the high
Directional Terms:
Caudal
The tail (Coccyx)
the hips are Caudal to the waist
Directional Terms:
Inferior
Below, at a lower point
The knees are inferior to the hips
Directional Terms:
medial
Toward the body's longitudinal axis; toward the midsagittal plane.
Moving medially from the arm across the chest surface brings you to the sternum.
Directional Terms:
Lateral
Away from the body's longitudinal axis; away from the midsaggital plane.
moving laterally from the nose brings you to the cheek.
Directional Terms:
Proximal
Toward an attached Base
the thigh is proximal to the foot.
Directional Terms:
Distal
Away from an attached base.
the fingers are distal to the wrist.
Directional Terms:
Superficial
At, near, or close to the body's surface
the skin is superficial to underlying structures.
Directional Terms:
Deep
Farther from the body surface
the bone in the thigh is deep within the muscle.
Directional Terms: Sectional Planes
Sagittal
Parallel to long axis
A Sagittal section separates right and left portions.
Functions of Body Cavity :
1.
2.
1. Protect organs from shock and impact.
2. permit changes in size and shape of organ.
Body Cavity: Ventral Body Cavity
Subdivides into ___ and ___ during early development
Thoracic Cavity
Abdominalpelvic cavity
Body Cavity: Thoracic Cavity
Surrounded by___and____
Conisists of: ___,___,___,___
1. Chest wall and diaphragm
2. Right Pleural Cavity, Mediastinum, Pericardial Cavity, Left Pleural Cavity
Body Cavity: Thoracic CavityRight Pleural Cavity: Surrounds ___
Right Lung
Body Cavity: Thoracic CavityMediastinum: Contains ___
the treachea, esophagus, and major vessels
Body Cavity: Thoracic Cavity
Pericardial Cavity: Surrounds ___
Heart
Body Cavity: Thoracic Cavity
Left Pleural Cavity: Surrounds ___
Left Lung
Body Cavity: Abdominopelvic Cavity
Contains ___,___,___
1. Peritoneal Cavity
2. Abdominal Cavity
3. Pelvic Cavity
Body Cavity: Abdominopelvic Cavity
Peritoneal Cavity: Extends throughout ___
abdominal cavity and into superior portion of pelvic cavity
Body Cavity: Abdominopelvic Cavity
Pelvic Cavity: contains ___, ___,___
1. Urinary bladder
2. reproductive organs
3. last portion of the digestive tract
Cavity Points to Note:
Serous membrane:
double-layered
Serous membrane:
Visceral layer:
covers & adheres to viscera
Serous membrane:
Peritoneum:
serous m. for abd-pelvic cavity
Surface Anatomy-
A type of Gross Anatomy. Study of general form and superficial markings.
Organ system-
groups of organs that function together in a coordinated manner.
Developmental Anatomy-
A type of Gross Anatomy. Describes the changes in form from conception and physical maturity.
What are the two major divisions of Microscopic Anatomy?
Cytology and Histology.
Cytology-
The study of internal structure of individual cells.
Histology-
examination of tissues.
Cells-
The smallest unit of life
Tissues
groups of specialized cells that work together to preform a specific function.
Tissues combine to form
Organs
Human Physiology-
Study of the functions of the human body
Levels of Organization:
The Chemical/Molecular Level-
Atoms
Levels of Organization:
The Cellular Level
Cells
Levels of Organization:
Tissue Level
Tissue
Levels of Organization:
Organ Level
Organs
Levels of Organization:
Organ System Level
Organ system.
Levels of Organization:
Organism Level
Organisms
Homeostasis
the tendency toward internal balance.
Homeostatic Regulation
the adjustment of physiological systems to preserve homeostasis.
Autoregulation-
intrinsic regulation. When a cell, tissue, organ, or organ system adjusts its activities in response to environmental change
Three parts of a Homeostatic Regulatory System-
1. Receptor
2. Control Center
3. Effector
Homeostatic Regulatory System:
Receptor (1st step)
a sensor that is sensitive to a particular stimulus/environmental change.
Homeostatic Regulatory System:
Effector (3rd step)
a cell or organ that responds to the commands of the control center and whos activity either opposes or enhances the stimulus.
State of Equalibirium
exists when opposing processes are in balance. example: in the body- rate of heat loss= rate of heat production.
Atoms
Smallest stable units of matter.
Major elements
(96% of you): O, C, H, N
Molecule:
combination of 2 or more atoms. Often will be atoms from same element
Enzyme:
special proteins that lower the activation energy of a reaction, speed it up. A type of catalyst. Generally end in “-ase”. Ex. Telomerase.
Inorganic Chemistry:
Simple smaller molecules
no C-H bonds
H2O, CO2, O2, acids, bases, salts
Organic Chemistry:
Complex (often larger) molecules, C-H bonds
Carbohydrates, lipids, proteins, nucleic acids
Water is the most-
Most abundant chemical in body
Physical/chemical characteristics of Water: 1-6?
Absorb/release heat slowly
Hydrogen bonds
Breaks ionic bonds
Solvent
Lubricant
Common in chem rxns
Hydrophilic:
“water-loving”
Hydrophobic:
“water-fearing”
Acid:
H+ donor (HCl, citric, acetic, ascorbic)
Base:
OH- donor (KOH, NaOH)
Acid + base =
neutral
pH:
measure of H+ in a solution
Scale:
Neutral:
Physiological:
Scale 0-14 (log)
Neutral: 7
Physiological: 7.4
Buffer:
can absorb excess H+ (if too acidic) or release H+ (if too basic) to maintain pH- example of this is Carbonic acid-bicarbonate system
Carbohydrates:
Family of organic compounds that includes sugars, starches, glycogen, & cellulose
Carbohydrates: are an important source of
energy
Carbohydrates are made of rings of :
have a _:_ ratio
example:
Made of rings of C, H, O
1:2:1
C6H12O6: glucose
Lipids are Hydrophobic or Hydrophillic? Why?
Hydrophobic (C-H groups non-polar)
Lipids: Phospholipids Diagram
Lipids: Phospholipids Diagram
Ribonucleic acid
(RNA)—the builders
ATP is the
Energy currency
Cytology
The study of cells
The Cell:
Plasma/Cell membrane: General functions
1. Physical isolation
2. Regulation of exchange of material between inside and outside
3. Sensitivity to the environment
4. Structural support.
Plasma Membrane:
Functions
Barrier btwn inside, outside of cell
Regulate exchange w/ environment
Receive signals (chemical, mechanical)
Plasma Membrane:
Membrane structures - support function
Phospholipid bilayer: barrier
Cholesterol: reinforce barrier, anchors proteins
Proteins: control entry, receive/transmit signals (receptors), anchor, recognition, enzymes
CHOs: lubricate, protect, anchor
Plasma Membrane:
Phospholipid bilayer:
barrier
Plasma Membrane:
Proteins:
control entry, receive/transmit signals (receptors), anchor, recognition, enzymes
Plasma Membrane
CHOs:
lubricate, protect, anchor
Plasma Membrane:
Integral Proteins
Span the width of the membrane one or more times- transmembrane proteins.
Plasma Membrane:
Anchoring Proteins
attach the plasma membrane to other structures and stabilize its position.
Plasma Membrane:
Recognition Proteins
recgonize other cells as normal or abnormal.
Plasma Membrane:
Receptor Proteins
are sensitive to a specific extracellular molecule
Plasma Membrane:
Carrier Proteins
bind solutes and transport them across the membrane
Plasma Membrane:
Channels
an integral protein with a central pore that forms a passageway across the membrane.
Nucleus:
Nuclear envelope:
Double-bilayer membrane
Nucleus:
Nucleolus:
produce RNA, ribosomes
Ribosomes: are responsible for ___.
Ribosomes: are responsible for protein synthesis.
Endoplasmic Reticulum (E.R.) is a network of ___ connected to the nuclear ___, which surrounds the nucleus.
Endoplasmic Reticulum (E.R.) is a network of intracellular membranes connected to the nuclear envelope, which surrounds the nucleus.
Membrane Transport: Review of Plasma Membrane
impermeable:
lets nothing in or out
Membrane Transport: Review of Plasma Membrane
freely permeable:
lets anything in or out
Membrane Transport: Review of Plasma Membrane
selectively permeable:
restricts what/when molecules move across membrane
Intracellular: ___the cells
Interstitial: ___cells
Plasma: in the ___
Intracellular: inside the cells
Interstitial: between cells
Plasma: in the blood
Solutions:
Solvent: liquid that ___
Usually water
Solutions:
Solvent: liquid that dissolves
Usually water
Solutions:
Solute: ___material
Ions, gases, molecules
Solutions:
Solute: dissolved material
Ions, gases, molecules
Solution:
Concentration: amt of ___in given volume of ___(abbrev: [ ])
Ex: teaspoons of salt per cup of water
Concentration: amt of solute in given volume of solvent (abbrev: [ ])
Ex: teaspoons of salt per cup of water
when solutes Move “down [ ] gradient”—no ___required
when solutes Move “down [ ] gradient”—no ATP required
Equilibrium: all solutes ___
equally distributed
Diffusion: move something ___[ ] gradient
Diffusion: move something down [ ] gradient
Simple Diffusion:
Simple (hydrophobic/non-polar)
Facilitated Diffusion:
Facilitated (charged, hydrophilic/polar)
Osmosis:
mvmt of water down [ ] gradient
what affects diffusion
what affects diffusion
What affects Diffusion?
DEP
Distance
Electrical forces
Permeability
Simple Diffusion
Think food coloring in water or perfume in air.
Passive Transport: Simple Diffusion
Requirements for simple diffusion:
Solute travels ___[ ] gradient
Solute able to ___ diffuse thru cell membrane
Passive Transport: Simple Diffusion
Requirements for simple diffusion:
Solute travels down [ ] gradient
Solute able to freely diffuse thru cell membrane
Passive Transport: Simple Diffusion
Pass right through ___.
Lipid-soluble molecules
O2, CO2
Fatty acids, steroids
Vitamins A,D,E,K
Passive Transport: Simple Diffusion
Pass right through lipid bilayer
Lipid-soluble molecules
O2, CO2
Fatty acids, steroids
Vitamins A,D,E,K
Passive Transport: Simple Diffusion
Passive Transport:Facilitated Diffusion
Passive Transport: Osmosis (Movement of Water):
Membrane must be ___ to water
Passive Transport: Osmosis (Movement of Water):
Membrane must be permeable to water
Osmosis: Water moves ___its [ ] gradient.
Area of ___water molecules to ___molecules.
i.e., from area of low solute [ ] to high solute [ ]
Osmosis: Water moves down its [ ] gradient
Area of more water molecules to fewer molecules
i.e., from area of low solute [ ] to high solute [ ]
Osmotic pressure: force of water movement due to ___
Osmotic pressure: force of water movement due to osmotic gradient
Osmosis: Tonicity
Osmosis: Tonicity
Hypertrophy is the increase in the ___of a cell due to the enlargement of its ___. This is seen in Interphase.
Hypertrophy is the increase in the volume of a cell due to the enlargement of its component cells. This is seen in Interphase.