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101 Cards in this Set

  • Front
  • Back
3 reasons we process air as we breathe?
trap bacteria, warm air, and humidify air
why is the epithelium cilliated?
to sweep mucus up
pharnyx?
structure where digestive and respiratory tracts cross
epiglotus?
glap the vocers the glotus, the hole at the top of the larnyx
larnyx
air goes thru hear as we talk
rings of cartlidge?
support tube to keep them from collapsing as you breate in under negative pressure
-support 1,2,and tertiary bronchi
bronchioles
not supported by cartlidge bc they are narrow and surrounded by thissue
lead to aveoli
aveoli
where 02 crosses into the blood strem and CO2 into the respiratory tract
-begining of respiratory division
lowering pressure in lungs?
to increase the volume for air
use muscles: pull diaprham tight and use externa glonocosta to pull up on ribs
Boyles law?
Pressure is proportional to 1/V
stemoclatols
used to pull on on ribs for really deep breathing
compliance?
ability of lungs to stretch when pulled on
what regulates the respiratory system?
the ANS and Central(medula)/peripherial(aorta) chemo receptors that sense pH and O2 concentration
low pH, what do lungs do?
means we have too much C02, so wee need to breathe more
What regulates breathing in?
brain stem
what regulates breathing out
natural, except Hering Brever Reflex in babies
how do we make it easier to eachange air? (3)
increase temp
increase surgace area
increase partial pressure of O2
what do we warm our air?
b/c at a higher temperature, gas disoved in water better
what is necessary before gas can disove across a membrane? why is this a problem? solution?
wetness
-can make aveoli colapse
-soln: make surfact w/ type II cells that reduces surface tension- made at about 8 mths pregnant
at high partial pressure, mor eor less 02 is available?
more
How many membranes are involved in the whole process of hemoglobin unloading?
5
path of hgb undloading
02 diffuses in aveoli, 02 diffuses out aveoli, 02 diffuses in endothelia, 02 diffues out endothelia, 02 diffues in RBC
what is the concentration gradient one we have made oxyhemoglobin?
steep concentration greadient for 02 going in to blood and Co2 coming out of blood
How does hgb know to load/unload? (3)
temp (active tissue= hot,unload 02)
conc gradient
pH (unloads at low pH-need for 02)
what is made when co2 combines with water?
carbonic acid, which lowers the pH
Pneumonia?
infection of the lung, which casues them to sweel to stop the spread of the diseas
emphysema?
when a duct sweels shut and lower pressue which burts aveoli. Then you get scare tissue which irritates more tissue. Ultimately leads to less compliance
pulmonary fibrosis?
inhaling sharp things/dust causes purmanet damage b/c you can't breathe these things out
What makes up the plasma?
plasma proteins, other solutes, water
what is the role of water in plasma?
to transport molecules, formed elements and heat
What makes up the blood
plasma (connective tissue matrix) and formed elecemts
what are the formed elemebts?
mostly RBC, white blood cells, platelets
plasma=
whole blood-formed elements
serum=
whole blood-formed elecemts- clotting proteins
what is the role of albumin
most prominent plasma protein
Contributes to osmotic pressure
buffer
role of globulins?role of fibrogen?
globulins-bind for transport
fibrinogen-clotting
what are platelets/trombocytes
peice of cells that contain a tertiary granule that is released when the are broken open when stuck to rough/negatively charged surface
what is uniqe about RBC?
no organelles (including nucleusb/c they are all squeezed out by gemoglobin)
How are red blood cells recycled?
they are recycled in the spleen
-reuse Hb and iron
-send rest to liver to excrete as poart of bile
what is jaundice?
can't get rid of bile (or Hgb rings), so you have yellow ish collor
two roles of the immune system
-eat and attack foreign cells
-make antibodies to eat/attack foregin cells
what is intrinsic clotting pathway?
--onnly need things found in blood--
1. cut/negative surface(cell damage) causes plateltes to stick
2. platelts break open
3. tertiary granules are released and have positive feed back on platelts as well as secreting serotonin for blood vessel constriction
4. cascade
5. Thrombin and fibrinoge combine to make fibrin which causes a clot
heparin?
blocks formation of thrombin-only effective on a small scale
plasmin-breaks down firbrin/blood clots
only effective on a small scale
Extrinsic (slow) clotting pathway
the injured tissure releases thromoplatin which eventualy combines thrombin and fibrinogen to make fibrin
arteries? when oxygen rich
Take blood away from the heart
-oxygen rich-systemic
-oxygen poor- pulmonary
veins? when oxygen poor?
take blood to the heart
-systemic oxygen poor
-pulmonary oxygen rich
3 layers of vessels
endothelium(smooth and thin)
Muscle- regulate flow of blood, stimulated to contract by aldosterone (which is responsible to stop loow blood pressure)
-Connective tissue-positive pressure so it keeps things from bursting
Differnece btwn layers of artery and veins?
artery-thick muscle and thin connective tissue
vein-thin musslce and thing connective tissue
force of arteries
contraction of heart
force of veins?
surrounding tissue and one way valves (brathing pushes on inferior vena cava
which of the formed elements can fit thru capilaries?
WBC
can albumin fit thru capilaries?
no
Opposing forces of capillary beds? when does each win?
arterial end-hydrodstatic pressure from heart-pushes things out
venule end-osmotic pressure wins, pulls water in
what do we do to absorb extra fluid and avoid edema
lymphatics catch extra and dumps in into the vena cava
what is elephantitis?
when a work blocks your lymphs so you get edema
heart cycle?
inferior vena cava: right atrium: right ventricle: pulmonary arteries: lungs: superior vena cava: pulmonary veins: left atrium: left ventriccle: aorta: systemic artieries: systemic veins
AV valves
-things can't get back into atria
-shuts w/ high pressure in ventricle
-have hearts strings/tendon chordae to witchstand extra pressure
semilunar valves
things can get back into ventricle
-shut when ventricle pressure is low
Lub sound
shut of AV valves when ventricles contract/are in systole
dub sound
shutting of semilunar valves when centricles relax/are indiastole
heart cycle in systole/diastole terms?
atrial systolye: atrial diastole/ventricale systole(Lub): ventrical diastole (dub)
heart murm? 1st slosh vs. 2nd slwsh?
blood leavking back into valves
1st slosh: AV valve error
2nd slosh: Semilunar valve error
foramen ovale?
whole btwn right atrium and left atrium in fetus b/c most of the blood doesn't go to the non functioning lungs, it is oxygenated in the placenta
What allows cytoplasm to be continuous so that action potential propagates thru all the cells of the heart at once?
-curvey/branced fibers
-ntercalated disks
What stimulates the heart?
conducting fibers (no nerves) that carry an action potential. They develop out of mesoderm/are muscle
what initiates/controls hear beat
the SA node
What does epi/norepi do to heart beat?
SNS-increases
what does ACh do to heart beat
PSNS-decreases it
Conduction in heart
SA Node: AP: Atria Contract: AV node delays to allow atria to relax: AV bunle of his: Purkinje fibers: Ventricle depobarizes w/ very coordinated contraction
P wave
atrial depolarization
QRS wave
ventrical depolarization
what makes distance btwn p and q longer?
bundle of his doesn't work and it takes longer to depolarize
diastolic blood pressure
-pressure in btwn heartbeats due to volume of blood
systolic blood pressure
diastolic + contraction of heart force--decreased by ACh
Alimentary canal?
runs from mouth to anus
4 layers of alementary canal
mucosa-slipery and traps pathogens

submucosa-highly intervated/vascularized: sensitive to HCl (ulcer) and blood absorbs broken down nutrients
constains lymphatics to absorb fats

Musclaris-smooth muscle w/ peristalic contractions in both directions(2 layers)

Adventicia- toufh fibers for protection w/ sirius fluid for reduced firction
digestive pathway
pharynx, esophogause, small intestine, colon, anus
what are the physical break down mechanisms of the mouth?
teeth and ridges of the pallet
what are the chemical breakdown mechanisms of the mouth?
salyvia w/ water, mucous, acid pH(kill bacteria)and salivary amylase to turns starches to sugar
whats broken down in the mouth?
carbs
esophagous
transport only!
Fxn of stomach
break down but very little absorption
chief cells
in stomach to make pepsinogen which, when added to HCL, makes pepsin to break down peptides
pariteal cells
in stomach to make HCl which converts pepsiongen to pepsin
Gastrin
made when stomach is stretched to stimulate the release of pepsinogen/hcl
what is stomach growling?
when food stimuli cause stomach to make gastrin and muscular layer contraction
what absoprtion takes place in the stomahc?
very little: water, some sugars, alcohol and caffine
What happens in the duodenum?
add things to chyme (bile, pancreatic enzymes, hormones_
what is done to chyme as soon as it enters the small intestine?
bile, to neutralize the acid, from the gall bladder, made in the liver
secretine
hormone made in the mucosal level of the duodenum-released during contact w/ low pH cyme to stimulate pancreatice enzymes and liver to make more bile
CCK
made in mucosal layer of the duodenum--released at contact w/ fat--stimulates gall bladder to break up fats to be absorbed and realse more bile which absorb fat
What makes up bile?
1. Lecithin-fath emulsifier
2. acid neutralizers
3. cholesterol
what are the dangers of cholesterol?
1. attracts calcium that causes hardening of the arteries
2. can percipitate out when mixed w/ calcium causing gall stones which can be wedged into bile ducts causing less bile secretion and more contractions of bile (jaundice/pain)
Roles of the liver
1. makes bile
2. 1st stopping point for nutrients absorbed from small intestine
3.storage (nutrients, glycogen, irons/vitamins)
4. converts amino acids to urea
5. makes blood proteins (albumin)
6. detoxifies
7. removes bateria
8. transforms aa to diff aa, turns fa to different fa
roles of jejunum and illeum
-absorption (villi and textured cells on membrane)
-chyme going thru here must be liquid so water is added to it
role of colon/large intestine
-reabsorps the water by actively reapsorbing sals (water folows)
diarrhea
irritation of colon/swelling so that water can't be absorbed
having a diet w/ lots of fibers (not absorbable) that pull water into feces when we want to reabsorb it
What causes constipation?
being sedentary so that the chyme spends more time in colon w/ water being socked out
-don't drink enough water so colon has to observe mmore?
Ecoli
-give us vitamin K for coagulation
-crowd out bad bacteria
-digest excess lactose/glycoproteins-makes gass
why are peanut allergies increasing?
soy and peanuts in baby formula are similar to glycoproteins creating an immune response