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74 Cards in this Set

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What is adrenaline?

A naturally occurring alpha and beta adrenergic stimulant

What are adrenaline's Beta 1 actions?

Beta 1 increases


- SA node firing rate


- AV conduction velocity


- Irritability of ventricles


- Myocardial contractility

What are adrenaline's Beta 2 actions?

Bronchodation

What are adrenaline's Alpha actions?

Peripheral vasoconstriction

Contraindications for adrenaline?

Hypovolemic shock without adequate fluid replacement

What are the precautions for adrenaline?

Cardiovascular disease


Higher dose maybe required for beta blocked patients


Elderly/frail


Monoamine oxidase inhibitors

C.H.E.M

What are the side effects of adrenaline?

Sinus tachycardia


Supraventricular arrhythmia


Ventriclar arrhythmia



Increased BP


Increased pupil dilalation


Increased size of MI



Feeling of anxiety/palpitations

3 rhythms


3 increases and one with feeling!

What is Aspirin?

An analgesic, antipyretic, anti inflammatory and antiplatelet agitation agent

4 A's

What are the contraindications for Aspirin?

Chest pain associated with psychostimulant OD with BP>160


Hypersensitivity to Aspirin/salicylates


Active bleeding peptic ulcers


Bleeding disorders


Suspected dissecting aortic aneurysm

C.H.A.B.S

What are the precautions for Aspirin?

Pts on anticoagulants


Asthma (current)


Peptic ulcers

P.E.P

What are the side effects of Aspirin?

Heart burn/Nausea/GI bleed


Increased bleed time


Hypersensitive reactions

Hi, H

What is ceftriaxone?

Cephalosporin antibiotic (broad spectrum)



Used in the treatment for ?) meningococcal and severe sepsis

What are the contraindications for ceftriaxone?

Hypersensitivity to cephalosporin antibiotics

Only 1

What are the precautions for ceftriaxone?

Allergic to penicillin

Lots of elderly are allergic to this...

BONUS QUESTION!!



What are the different doses of ceftriaxone for adults and paediatrics?

1g for adults


50mg/kg paeds

What is dexamethasone?

A corticosteroid that relieves inflammatory actions and is also an immunosuppessent

What are the contraindications for dexamethasone?

Known Hypersensitivity

Only one...

What are the precautions for dexamethasone?

If the solution is soiled or discoloured = discard it...

Look at the pretty colours...

True or false?



Generally, will you see the effects of dexamethasone?

False, on set is 30-60 mins. This medication is used for long term care of the patient

What is Dextrose 10%?

A slightly hypertonic crystalloid solution.



Used in the hypoglycaemic Pt that CAN NOT administer oral glucose WITH IV access.

What are the contraindications for dextrose 10%?

NIL.

It's sugar...

What are the precautions for dextrose 10%?

NIL.

Seriously it's sugar...

What are the side effects of dextrose 10%?

NIL.

IT IS SUGAR!!!

BONUS QUESTION:



What must be done when administering dextrose 10%? And why?

Flush with 10mL saline before and after admin to minimise chances of necrosis of tissues.

What is Fentanyl?

Synthetic opioid

Not just fun... alternative to morphine

What are the contraindications for Fentanyl?

Known Hypersensitivity


Late 2nd stage labour

Only 2

What are the precautions of Fentanyl?

Monoamine oxidase inhibitors Addiction to opioids


Depression of Respiration



Current asthma


Hepatic impairment


Elderly/Frail


Rhinitis, rhinorrhea or facial trauma


M.A.D C.H.E.R

What are the side effects of Fentanyl?

Bradycardia


Apnoea


Rigidity of diaphragm and intercostals


Respiratory depression

B.A.R.R

What is Glucagon?

Naturally occurring peptide hormone in the body that is secreted by the pancreas that causes lipolysis and the conversation of glycogen to glucose in the liver.

What are the contraindications of Glucagon?

NIL.

It's a hormone that naturally occurs in the body.

What are the precautions of Glucagon?

NIL.

It is a naturally occurring hormone in the body

What are the side effects of Glucagon?

Nausea/Vomiting (rare)

G.I side effects when you get really hungry

BONUS QUESTION:



Why won't Glucagon always work in hypoglycaemia?

If Pt has no glycogen stored, or it has been used up there us nothing for the Glucagon to work on.

BONUS QUESTION:



When is Glucagon used?

Hypoglycaemia where Pt can not self admin glucose and unable to gain IV access



Anaphylaxis where adrenaline is ineffective with Pt remaining hypotensive due to heart failure/Pt on Beta Blockers

What is Glyceryl Trinitrate?

Smooth muscle relaxant causing:



- Vasodilation which encourages venous pooling reducing preload



- Atrial dilation reducing vascular resistance and arterial pressure

What is the effect of GTN?

Decreases myocardial oxygen demand.



Decreases systolic, diastolic & MAP whilst maintaining coronary perfusion.



Mild coronary artery dilation MAY improve blood flow to ischaemic areas



Uterine quiescence in pregnancy

What are the contraindications for Glyceryl Trinitrate?

BP <110 tablet, <90 Patch



HR >150, <50 excluding autonomic dysreflexia



VT, R) myocardial infarction, inferior STEMI with BP<160



Known Hypersensitivity


Viagra/Lavitra 1/7 or cialis 4/7

2x BPs


2x HRs


3x rhythms


2x Other

What are the precautions of GTN?

Previous administration?


Elderly/Frail


Recent MI


Concurrent tocolytics

P.E.R.C

What are the side effects of GTN?

Tachycardia


Hypotension


Headache


Skin flushing


Bradycardia

Think about the effects of GTN... (There are 5)

What is Heparin?

Anticoagulant, inactivates thrombin by binding to antithrombin III

What are the contraindications for heparin?

Bleeding disorders


Active bleeding excl. menstruation


Recent surgery/trauma <3/52


Known Hypersensitivity/allergy


Severe Hepatic impairment/disease, including oesophageal varices



Heprin Induced Thrombocytopaenia


Oral anticoagulants

B.A.R.K.S. H.O.

What are the precautions for Heprin?

Renal impairment

Only one, think number one...

What are the side effects of Heprin?

Bleeding


Injection site pain/bruising


Thrombocytopenia


Hypercalcaemia

B.I.T.H

What is Ipratropium Bromide?

Anticholinergic bronchodilator



- blocks vagal response mediating bronchoconstriction

What are the contraindications of Ipratropium Bromide?

Known Hypersensitivity to Atropine/derivatives

Only one

What are the precautions of Ipratropium Bromide?

Avoid contact with eyes


Glaucoma

Think side effects...

What are the side effects of Ipratropium Bromide

Head aches


Acute angle glaucoma (rare)


Dry mouth


Nausea


Tachycardia (rare)


Palpitations (rare)


Rash

Head to toe (7 points)

What is Ketamine?

Anaesthetic agent with analgesic effect at lower doses

What are the contraindications for Ketamine?

Suspected non traumatic brain injury with BP >180

Only 1

What are the precautions for Ketamine?

May exacerbated cardiac conditions due to effect on HR & BP

Only 1

What are the side effects for Ketamine?

CV: tachycardia & hypertension



CNS: emergence reactions (euphoria etc.), increased skeletal tone (looks like seizures)



Resp: transient Resp depression & apnoea (rare)



GI: Nausea and Vomiting



Other: pain @ injection site, lacrimation, hypersalivation, diplopia, nystagmus

BONUS QUESTION:



True or False, can you use Ketamine on pregnant Pts?

Ketamine is considered safe for pregnant Pts and only requires monitoring for breastfeeding Pt

What is Methoxyflurane?

Inhalation analgesic agent in low concentrations

What are the contraindications for Methoxyflurane?

Concurrent use of tetracycline antibiotics


Exceeding 6ml in 24hrs


Muscular dystrophy


Pre-existing renal disease/impairment


Personal/family history of malignant hyperthermia

C.E.M.P.P

What are the precautions for Methoxyflurane?

Penthrox inhailer must be held by the Pt


Pre-eclampsia


Concurrent oxytocin may cause hypotension

P.P.C.

What are the side effects for Methoxyflurane?

Bradycardia and hypotension


Exceeding 6mL in 24hrs may cause renal toxicity


Drowsiness

B.E.D

What is Midazolam?

Short acting CNS depressant (benzodiazepine)

What are the contraindications for Midazolam?

Known Hypersensitivity to benzodiazapines

Only 1

What are the precautions for Midazolam?

Reduced dose for Pts:


- renal failure


- Elderly/frail


- CCF


- Shock



CNS depressant effects are increased when mixed with narcotics, tranquillisers including alcohol



Can cause severe resp depression in COPD Pts



Pts with myasthenia gravis (muscular weakness due to breakdown of nerves and muscles)

What are the side effects of Midazolam?

CNS Depression


RESP Depression


Hypotension


Loss of airway control

2x Depressions leads to loss, H

What is Morphine?

Opioid analgesia

What are the contraindications for morphine?

Renal impairment/failure



Known Hypersensitivity



Late 2nd stage labour

Fentanyl plus 1

What are the precautions for morphine?

Hypotension


Elderly/frail


Respiratory depression



Current asthma


Respiratory tract burns


Alcoholism


Pts on Monoamine oxidase inhibitors


Known addiction

H.E.R C.R.A.P

What are the side effects of Morphine?

Drowsiness


Respiratory depression



Hypotension


Bradycardia



Nausea/Vomiting


Addiction


Pin point pupils


Euphoria

D.R. H.B N.A.P.E

What is Naloxone?

Opioid antagonist

What are the contraindications for Naloxone?

NIL.

Pts will claim this but it's not true

What are the precautions for Naloxone?

Pts that are addicted can be combative



Neonates

Long term and short-term users

What are the side effects of Naloxone?

Convulsions


Nausea/Vomiting


Agitation


Dilation of pupils with lacrimation (teary)


Sweating, goose flesh, tremor

C-N.A.D.S

What is Olanzapine?

Atypical antipsychotic used for mild agitation

What are the contraindications for Olanzapine?

NIL

What are the precautions for Olanzapine?

Alcohol and other narcotics on board will result in Olanzapine being not as effective. (Midaz front-line)



Elderly/frail are more susceptible to adverse effects

What are the side effects of Midazolam?

CNS: sedation and dizziness



Other: extrapyramidal symptoms and QT prolongation

What is Ondansatron?

Anti-emetic

What are the contraindications for Ondansatron?

Concurrent apomorphine use (parkinsons)


Hyperkalaemia/hypomagnesia


Long QT syndrome


Hypersensitivity

C.H L.H