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25 Cards in this Set

  • Front
  • Back

Adrenaline Pharmacology

Adrenaline is a naturally occurring alpha and beta-adrenergic stimulant.


Its actions are:


* Increase heart rate by increasing firing rate of the SA node.
* Increases the conduction velocity through the AV node
* Increases the myocardial contractililty
* Increases the irritability of the ventricles.
* Causes bronchodilatation (beta 2)
* Causes peripheral vasoconstriction (Alpha)

Aspirin Pharmacology

An Analgesic, antipyretic, anti-inflammatory and antiplatelet aggregation agent

Actions:


* To minimise platelet aggregation and thrombus formation in order to retard the progression of coronary artery thrombosis in ACS.

* Inhibits synthesis of prostaglandins - anti-inflammatory actions.

Ceftriaxone Pharmacology

Cephalosporin antibiotic

Dextrose 10% Pharmacology

A slightly hypertonic crystalloid solution


Composition: Sugar - 10% dextrose and water


Actions: Provides a source of energy, supplies the body with water

Fentanyl Pharmacology

A synthetic opioid analgesic.


Actions:


CNS Effects


* Depression - leading to analgesia

* Respiratory depression - leading to apnoea

* Dependence (addiction)

* Decreased conduction velocity through the AV node

Glucagon Pharmacology

Glucagon is a hormone naturally excreted by the pancreas.


Actions: Causes an increase in blood glucose concentration by converted stored liver glycogen to glucose.

Glyceryl Trinitrate (GTN) Pharmacology

Principally, a vascular smooth muscle relaxant.


Actions:


* Venous dilation, promoting venous pooling, reducing venous return (decreased preload)

* Arterial dilation reducing systemic vascular resistance (decreased after load)

* Reduced myocardial O2 demand

* Reduced systolic, diastolic and mean arterial pressure whilst usually maintaining coronary perfusion pressure.

* Mild-collateral coronary arterial dilation may increase blood supply to ischemic area or myocardium.

* Mild tachycardia secondary to a drop in BP

* Preterm Labour: Uterine quiescence in pregnancy.

Ipratropium Bromide Pharmacology

Anticholinergic bronchodilator.


Actions: Allows bronchodilations by inhibiting cholinergic bronchomotor tone. (i.e. blocks vagal reflexes which mediates bronchoconstriction).

Lignocaine 1% Pharmacology

Lignocaine is a local anesthetic agent.


Actions: Prevents initiation and transmission of nerve impulses, causing local anesthesia (1% solution)

Methoxyflurane Pharmacology

Inhalation analgesic at low concentrations

Midazolam Pharmacology

Short acting CNS depressant


Actions:


* Anxiolytic

* Sedative

* Anti-convulsant

Morphine Pharmacology

An opioid analgesic


Actions:


CNS Effects


* Depression (leading to analgesia)

* Respiratory depression

* Depression of cough reflex

* Stimulation (changes of mood, euphoria or dysphoria, vomiting, pin-point pupils)

* Dependence (addiction)

* Vasodilation

* Decreased conduction velocity through the AV node

Naloxone Pharmacology

An opioid antagonist


Actions:


* Prevents or reverses the effects of opioids

Normal Saline Pharmacology

An isotonic crystalloid solution


Composition:


* Electrolytes (sodium and chloride in a similar concentration to that of extracellular fluid)

* Increases the volume of the intravascular compartment

Paracetamol Pharmacology

An analgesic and antipyretic agent
Actions: Exact mechanism of action are unclear; thought to inhibit prostaglandin synthesis in the CNS.

Prochlorperazine Pharmacology

An anti-emetic


Actions:


* Act on several central nervous neuro-transmitter systems

Salbutamol Pharmacology

A synthetic beta adrenergic stimulant with primarily beta 2 effects.


Actions:


* Causes bronchodilatation

Water for Injection Pharmacology

Water for injection is a clear, colourless, particle free, odourless and tasteless liquid. It is sterile, with a pH of 5.6 to 7.7 and contains no antimicrobial agents.

Ondansetron Pharmacology

Anti-emetic


Action:


5HT3 antagonist which blocks receptors both centrally and peripherally.

Oxytocin Pharmacology

A synthetic oxytocic.


Actions:


Simulates smooth muscle of the uterus producing contractions.

Heparin Pharmacology

Anticoagulant, inactiaves clotting factors IIa (thrombin) and Xa by binding to antithrombin III.

Tenecteplace Pharmacology

Fibrinolytic, a modified form of a tissue plasminogen activator (tPA) that binds to fibrin and converts to plasminogen to plasmin.

Dexamethasone Pharmacology

A corticosteroid secreted by the adrenal cortex.
Actions:

Relieves inflammatory reactions


Provides immunosuppression.

Ketamine Pharmacology

Anaesthetic agent with analgesic properties at lower doses.


Exact mechanism pf action is uncealr, but primarily works as an antagonist at N-methyl-D-asparate (NMDA) receptors.


Ketamine may also interact with opioid, muscarinic and other receptors. Produces a trance-like dissociative state with amnesia, with preservation of laryngeal and pharyngeal reflexes.

Olanzapine Pharmacology

Atypical antipsychotic - antagonist at multiple receptor sites, particularly serotonin (5-HT), dopamine and histamine.