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103 Cards in this Set

  • Front
  • Back

Adrenaline

mixed adrenergic agonist


Injectible

noradrenaline

mixed adrenergic agonist


Injectible


No B2 effects

dopamine

mixed adrenergic agonist


Injectible

phenylpropanolamine

mixed adrenergic agonist


Oral suspension

Pseudoephedrine

A1 agonist


Oral

Dobutamine

B1 agonist


Injectible


very short acting

Terbutaline

B2 agonist


Oral suspension, aerosol, subcutaneous

salbutamol

B2 agonist


Aerosol

Salmeterol

B2 agonist


Aerosol


Longer-lasting, equine

clenbuterol

B2 agonist


Injectible, oral gel

Phenoxybenzamine

a1 antagonist


Oral capsule


Aids urinary continence (relaxes smooth muscle component of urethral sphincter)

Bethanecol

Parasympathomimetic


Muscarinic agonist


Tablet


Primarily to aid urination but can't be used with blocked bladder.

Cisapride

Parasympathomimetic


Triggers ACh release from myenteric plexus


Tablet


Increased gut motility

Atropine

Parasympatholytic


anti-muscarinic


Injectible, topical (eyes)

Tropicamide

Parasympatholytic


anti-muscarinic


Topical (eyes)


Retinal examination

Glycopyrrolate

Parasympatholytic


anti-muscarinic


Injectible


Less lipophilic than atropine (less CNS effects)

Neostigmine

Acetylcholine esterase inhibitor


injectible

Pyridostigmine

Acetylcholine esterase inhibitor


tablet

Edrophonium

Acetylcholine esterase inhibitor


Injectible

Succinylcholine

Anti-nicotinic


Injectible


Depolarising neuromuscular blocker

Atracurium

Competitive anti-nicotinic


Injectible


Can be out competed by neostigmine

Digoxin

+ve inotrope


Tablet or injectible



Pimobendan

+ve inotrope


Tablet or injectible


Vet-exlusive

Benazipril

ACE Inhibitor (vasodilator)


Tablet

Atenolol

Beta blocker


Tablet


More selective for b1

Propanolol

Beta blocker


Tablet

Amlodipine

Calcium channel blocker


Tablet


Feline hypertension

Nitroglycerine

Nitrate (vasodilator)


Topical, sublingual tablet, oral spray


Often applied on inner ear

Nitroprusside

Nitrate


Injectible

Prazosin

a1 antagoinst (vasodilator)


tablet

Quinidine

Sodium channel blocker

Procainamide

Sodium channel blocker



Sotalol

Beta-blocker + potassium channel blocker

Diltiazem

Calcium channel blocker


Tablet

Amiodarone

Potassium channel blocker

Frusemide

Loop diuretic


Tablet, injectible, oral liquid

Manitol

Osmotic diuretic


Injectible

Spironolactone

Potassium-sparring diuretic


Tablet

Ammonium chloride

Urinary acidifier


Tablet

Diazepam

Benzodiazepine


Injectible, tablet

Midazolam

Benzodiazepine


Injectible

Flumazenil

Benzodiazepine antagonist


Injectible

Acepromazine

Neuroleptic


Injectible

Medetomidine

a2 agonist


Injectible (IV or IM)

Dexmedetomidine

a2 agonist

Injectible


Chiral version of medetomidine with reduced CVS and increased CNS effects

Xylazine

a2 agonist

Injectible (IV)


Ruminant sensitivity

Detomidine

a2 agonist

Injectible


Longer DOA than xylazine + greater efficacy

Romifidine

a2 agonist

Injectible


Less ataxia than xylazine or detomidine

Yohimbine

a2 antagonist


Injectible


Xylazine reversing agent



Atipamezole

a2 antagonist

Injectible (NOT IV)


Medetomidine reversing agent

Guaifenesin

CNS drug of unknown MOA


Injectible

Methocarbamol

CNS drug of unknown MOA


Injectible, tablet


Antidote - used alongside atropine for acetylcholine esterase inhibitor toxicity

Tramadol

µ-agonist also slows uptake of serotonin and NAdr


Oral tablets/drops and injectible

Naloxone

Opioid antagonist


Reversal agent for opioid overdose

Fentanyl

µ-agonist


Strongest with shortest DOA (20-30mins)


Injectable and transdermal patch

Morphine

µ-agonist


DOA 3-4hrs, poor oral bioavailablity


Injectible

Methadone

µ-agonist


DOA 3-4hrs, good oral bioavailablity


Injectable and oral syrup

Codeine

Weak µ-agonist


Good oral bioavailablity


Mainly used as anti-tussive


Oral tablet/liquid and injectable

Pethidine

Weak µ-agonist


More commonly used in people


Injectable but not IV (particularly horses) as causes massive histamine release

Butorphanol

k-agonist, weak µ-antagonist


Good sedative with little analgesia in mammals


Better analgesia in birds


Injectable

Buprenorphine

partialµ-agonist, weak k-antagonist


Slower onset but extended DOA (up to 10hrs)


Injectable as well as transdermal patch

Thiopentone

Barbiturate


IV general anaesthesia


Injectable



Pentobarbitone

Barbiturate


Euthanasia solution/backup anticonvulsant


Injectable

Alfaxalone

Neurosteroid - GABA agonist


IV general anaesthetic


Injectable

Propofol

GABA agonists


IV general anaethetic/backup anticonvulsant


White drug that goes IV


Injectable

Ketamine

Disassociative


IV general anaesthetic


Injectable and oral

Tiletamine - Zolazepam

Disassociative + benzodiazepine


IV general anaethetic


Injectable

Halothane

Inhalant GA


Slowest induction and adjustment


Rarely used in SAs - mainly only used in horses


Gas

Isoflurane

Inhalant GA


Moderate induction and adjustment


Used wildlife and birds - irritates airways


Gas

Sevoflurane

Inhalant GA


Moderate induction and adjustment


Does not irritates airways


Gas

Desflurane

Inhalant GA


Fastest induction and adjustment but requires specialised equiptment to use


Gas

Potassium bromide

Oldest anticonvulsant with unknown MOA


Oral medication that requires significant loading dose

Levetiracetam

New anticonvulsant with unknown MOA


Able to supress seizures without affecting normal neuronal excitability


Injectible or oral tablets

Gabapentin

New anticonvulsant with unknown MOA


Very few side effects also indicated or neuropathic pain


Oral tablets

Imepitoin

Partial agonist at benzodiazepine receptor


Anticonvulsant with little drug tolerance


Oral tablets

Clomipramine

Trycyclic antidepressant


Only one registered in vetmed


Oral tablets

Amitriptyline

Trycyclic antidepressant


Used off-label in vetmed


Oral tablets

Fluoxentine

Selective serotonin reuptake inhibitor


Selective for serotonin so fewer side effects than TCA


Oral tablets

Selegiline

Monoamine oxidase type B inhibitor


Slows breakdown of dopamine


In-feed additive

Medroxyprogesterone

Progesterone analogue


Long-acting depot effect


Injectable

Propentofylline

Methylxanthine derivative


Indicated for canine cognitive dysfunction


Oral tablet

Feline facial pheromone analogue

Synthetic feline pheromone


Spray and infusor

Dog appeasing pheromone

Synthetic canine pheromone


Spray and collars

Lignocaine

Na channel blocker


Local anaethetic and anti-arrhythmic


Fast acting


Injectable

Buprivicaine

Na channel blocker


Local anaesthetic


Longer DOA than lignocaine


Injectable

Mepivacaine

Na channel blocker


Local anaesthetic


Less irritating than lignocaine


Injectable

Proxymetacaine

Na channel blocker


Local anaethetic


Epitheliotoxic


Topical (ocular)

EMLA

Na channel blocker


Local anaesthetic


Slow onset of action but good absorption through intact skin


Topical

Meloxicam

NSAID (non-COX-1 sparing)


Variety of concentrations available


Oral and injectable preparations

Carprofen

NSAID (non-COX-1 sparing)


Variety of concentrations available


Oral and injectable preparations

Firocoxib + Deracoxib

NSAID (COX-1 sparing)


Only registered in dogs


Oral tablets

Robenacoxib

NSAID (COX-1 sparing)


Registered for dogs and cats


Oral and injectable preparation

Mavacoxib

NSAID (COX-1 sparing)


Extremely long-acting (monthly after loading dose)


Oral tablets

Tolfenamic Acid

NSAID (COX-1 sparing)


Used in production animals


Injectable

Flunixin

NSAID (non-COX-1 sparing)


Used in production animals


Injectable

Phenylbutazone

NSAID (non-COX-1 sparing)


Used for horses but not production animals


Injectable and oral paste

Pentosan polysulfate

Polysulfated Glycosaminoglycan


Injectable

Prednisolone

Corticosteroid


DOA 24-36hrs


All forms

Methyprednisolone

Corticosteroid


Depot effect (2-4 week DOA)


Injectable

Dexamethazone

Corticosteroid


DOA 72hrs


Injectable

(Hydro)cortisone

Corticosteroid


Rapid absorption through intact skin with low concentrations reaching systemic circulation


Topical

Fluticasone

Corticosteroid


Inhalant

Fludrocortisone

Mineralocorticoid-selective corticosteriod


Used for treatment of Addison's Disease