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30 Cards in this Set

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  • Back
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Expression
Cluster of signs, symptoms, and diseases
what is AIDS? and not the name ya retard lol
Syndrome includes:
rare vascular cancer (Kaposi’s sarcoma), rare pneumonia (Pneumocystis carinii), weight loss, lymphadenopathy, other cancers & diseases
a lotta shit...pne_____
and some cancers
History
First cases described in early 1980s
originated probably from two SIVs hybridizing
Epidemiology
worldwide stats
39.5 m – 47 m prevalence
4.3 m incidence in 2006
2.9 m deaths from AIDS in 2006
Epidemiology
US stats
1 m in U.S. prevalence
Stats flat
AIDS are fucking us up!!!
Etiology
Etiological Agent
HIV (Human Immunodeficiency Virus)
HIV (Human Immunodeficiency Virus)
spherical virus with lipid envelope
Two types of glycoprotein spikes pierce the envelope; knobs on spikes mediate adsorption
it's an incy wincy spiky ball!
HIVI and HIVII are...
retroviruses
old school shit
Expression
Cluster of signs, symptoms, and diseases
what is AIDS? and not the name ya retard lol
HIV family
HTLV (human lymphotropic viruses) - retroviruses
Syndrome includes:
rare vascular cancer (Kaposi’s sarcoma), rare pneumonia (Pneumocystis carinii), weight loss, lymphadenopathy, other cancers & diseases
a lotta shit...pne_____
and some cancers
History
First cases described in early 1980s
originated probably from two SIVs hybridizing
Type I and Type II of AIDS:
Leukemia and lymphoma
Epidemiology
worldwide stats
39.5 m – 47 m prevalence
4.3 m incidence in 2006
2.9 m deaths from AIDS in 2006
Type III
now called HIV
Epidemiology
US stats
1 m in U.S. prevalence
Stats flat
AIDS are fucking us up!!!
HIV is an obligate intracellular parasite;
it requires receptor to infect--CD4 receptor found on lymphocytes
Etiology
Etiological Agent
HIV (Human Immunodeficiency Virus)
Transmission
-passed through body fluids
Sexual contact (homo or hetero)
-Mother to child during pregnancy and through breast milk
-Needle sharing during drug use
-Blood products (now screened)
HIV (Human Immunodeficiency Virus)
spherical virus with lipid envelope
Two types of glycoprotein spikes pierce the envelope; knobs on spikes mediate adsorption
it's an incy wincy spiky ball!
NOT transmitted through:
urine, tears, sweat, saliva
yayyy!! let's makeout
HIVI and HIVII are...
retroviruses
old school shit
Pathogenesis
HIV
enters mucous membrane, travels to dendritic cell (phagocyte)
it's in my snot! and now my phag!
HIV family
HTLV (human lymphotropic viruses) - retroviruses
Type I and Type II of AIDS:
Leukemia and lymphoma
Type III
now called HIV
HIV is an obligate intracellular parasite;
it requires receptor to infect--CD4 receptor found on lymphocytes
Transmission
-passed through body fluids
Sexual contact (homo or hetero)
-Mother to child during pregnancy and through breast milk
-Needle sharing during drug use
-Blood products (now screened)
NOT transmitted through:
urine, tears, sweat, saliva
yayyy!! let's makeout
Pathogenesis
HIV
enters mucous membrane, travels to dendritic cell (phagocyte)
it's in my snot! and now my phag!