Adrenal Highlights

Front 1

Addison's disease
a.) etiology
b.) diagnosis

Back 1

a.) autoimmune disease or TB
b.) cosyntropin test. inject with ACTH, if cortisol increases <9 = primary adrenal insufficiency

Front 2

Addison's disease
a.) symptoms

Back 2

PVDS
hyponatremia, hyperkalemia, dehhyration, salt cravings, postural hypotension, decreased body hair, vitiligo, hypopituitarism (cold intolerance, amenorrhea), postural hypotension

Front 3

Addison's disease
a.) treatment (3)

Back 3

1.) hydrocortisone: 15-25 mg divided 2/3 AM 1/3 PM
2.) prednisone: 3-5mg divided 2/3 AM 1/3 OM
3.) fludrocortisone: 0.05-0.2 mg daily. take when hyperkalemia is bad

Front 4

Cushing's syndrome
a.) etiology
b.) diagnosis

Back 4

a.) ACTH dependent in the pituitary or endocrine. ACTH independent, adrenal tumor
b.) get a cortisol saliva test to see if high. then figure out etiology by looking at plasma ACTH levels. if ACTH low, then look at adrenal. if ACTH high, do a dexamethasone test to suppress the cortisol. if cortisol is decreased, look at the pituitary. if not suppressed, look at chest or abdomen

Front 5

Cushing's syndrome
a.) symptoms

Back 5

a.) moonface, peripheral obesity, HTN, osoporosis, mood changes

Front 6

Cushing's syndrome
a.) treatment (4)

Back 6

a.) steroidogenic inhibitors = ketoconazole or metyrapone
adrenolytics = mitotane
mifepristone

Front 7

Hyperaldosteronism
a.) etiology
b.) diagnosis

Back 7

a.) BAH (bilateral adrenal hyperplasia) or APA (aldosterone-producing adenoma)
b.) hypokalemia (serum K < 3.5, K excretion > 30mEq in 24 hours)

Front 8

Hyperaldosteronism
a.) symptoms

Back 8

a.) resistant HTN, paralysis, polyuria/polydipsia

Front 9

Hyperaldosteronism
a.) treatment

Back 9

a.) BAH = spironolactone, eplerenone, amiloride