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13 Cards in this Set

  • Front
  • Back

How is DTPA excreted?

By the kidney via GFR filtration


(neither secretion nor absorption)

List 4 indications for use of DTPA.

1. Determine GFRs


2. Determine functional of contralateral kidney


3. Rule out obstructive uropathies


4. Evaluate morphology

What are the routes of administration and acquisition modes for DTPA?

IV


Frame mode - Dynamic

How should the patient be positioned and what is the image timing for DTPA studies?

Left lateral

(camera dorsal to kidneys, then lateral for depth correction)


Image immediately post injection

When should peak renal activity be seen in normal patients?

~3 minutes

What is the percentage of its first pass extraction?

20%

(fast blood clearance)

What is the normal GFR value for dogs and cats respectively?

Dogs > 3mL/min/kg


Cats > 2.5mL/min/kg

What must GFR values be below in order to see azotemia on bloodwork?

< 1mL/min/kg

If renal blood flow (RBF) is reduced, how may the body adapt in order to maintain an acceptable GFR?

Vasoconstriction of the efferent arteriole.

What is average renal plasma flow?

15 mL/min/kg

List 4 reasons why imagine studies with DTPA are a superior clinical choice over plasma clearance studies.

1. 2 minutes of data (instead of 3 hours)


2. Can determine individual kidney GFRs


3. Can detect renal dysfunction before azotemia


4. It's just easier

For what species is depth attenuation correction important when calculating GFR?

Dog

What is the equation used to correct for background activity in order to determine true net kidney counts?

net kidney counts = gross counts kidney ROI - [(# pixels in kidney ROI)*(BKGRND counts/BKGRND pixels)]