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8 Cards in this Set
- Front
- Back
Classification of AHF |
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Escape Trial |
Routine use of PA catheter in acute HF didnt reduce hospitalization but inc adverse events. CI <2ml/min/m2 ~ cardiogenic shock PCWP > 16 ~ PUL edema |
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3CPO trial |
NIV (CPAP +Bipap) vs med Rx no difference in mortality but dec symptoms & respiratory dep . |
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Dose of thiazide diuertics |
Metolazone 2.5 to 10mg HCTZ 25-50mg Bid CTZ 250-500mg IV 500-1000mg ORAL spironolactone 25-50mg Acetazolamide o.5mg |
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Vasodilators in acute heart failure |
Vasodilator, venodilators, dec filling pressures, inc CO, dec preload and afterload. Nitroglycrine for epicardial coronaries Nitroprudside for intramyocardial vasculature. Coronary steal phenomenon. MAP>65mmHG SBP 90-100mmHG |
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Inodilators= inotropes with vasodilatory properties Levosimendan 0.5-2Microg/kg/min Milrinone o.125-o.75microg/kg/min |
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Vasopressors |
Norepinephrine o.2-1microg/kg/min Phenyephrine Dopamine high dose |
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Novel therapies for HF |
Vasodilators Serolaxin Urodilatin Ultratide Neurohormones Endothelin receptor antagonist Aliskerin Gyuanylate cyclase activator Veriguacit Cinaguacit Myosin activators Omecamdive mecarbil |