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15 Cards in this Set
- Front
- Back
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Neurilemmoma is also known as what?
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Benign schwannoma
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What are the three most common locations?
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Spinal nerve roots
Mediastinal nerves Retroperitoneal nerves |
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What are the four components of the general histologic appearance?
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Myxoid in soft tissue
Well encapsulated Two organized structural areas No mitotic figures |
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What are the two regions seen on histology called?
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Antoni A: highly ordered
compact spindle cells with twisted nuclei Antoni B: less orderly with a myxoid matrix |
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What are the characteristic bodies seen with neurilemmoma? Appearance?
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Verocay bodies
Palisading of nuclei around eosinophilic areas |
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What bodies are associated with Morton's neuroma?
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Renaut bodies
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What does neurilemmoma stain positive for?
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S-100
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How is neurilemmoma treated?
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Surgical resection of mass, sparing the nerve
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How many lesions are typically found in affected adults?
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Usually a solitary mass in adults
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How many lesions are typically found in patients with von Recklinghausen’s disease?
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Multiple nodules at different sites with different rates of growth
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What is the inheritance pattern of von Recklinghausen’s?
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AD
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What are two other key features of this syndrome?
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Café-au-lait spots
Cystic bone lesions |
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What other neoplasm do the bony lesions generally resemble?
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Nonossifying fibroma (NOF)
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What are the three typical histologic features of neurofibroma?
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No capsule (compare with neurilemmoma)
Spindle cells with rare mitoses S-1 00 positive |
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How frequently does malignant degeneration occur with neurofibroma?
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5 to 30% of cases
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