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21 Cards in this Set
- Front
- Back
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What is the difference between heparin and LMWH in treating PE?
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LMWH doesn't have to have PTT checked
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What is the dose of heparin for PE?
In heparin treatment for PE, how often do you check PTT at first? When stable? How often do you check platelets? |
80 U/kg bolus
16-18 U/kg IV infusion for 5 days at least Q6 QD every other day |
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What is the initial dose of coumadin for treatment of PE?
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10 mg
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How long do you anticogulate for a thrombotic event (PE, DVT)?
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minimum of 3 months
If second PE/DVT, indefinitely |
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PE patient with renal insufficiency should use [unfractionated, low molecular weight] heparin.
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unfractionated
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What are two anticoagulants which may soon become first line , thus ending INR checks?
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idraparinux
rivaroxaban |
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When should you consider thrombolytics in PE?
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shock or respiratory failure
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What medication should you check in a woman with a PE or DVT?
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oral contraceptives
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Only leading cause of death that is still on rise
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COPD (4th leading cause)
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Possible screen for smokers for COPD
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spirometry to determine "lung age"
Not so much because it's prognostic, but b/c telling them lung age increased their likelihood of quitting smoking |
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T/F active inflammation associated with COPD stops after 6 months of smoking cessation.
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False. It continues for years
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Systemic features of COPD
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CVD risk because of CRP elevation
Osteoporosis Puny blood (anemia) and muscle (wasting) Depression + normocytic anemia |
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What cardiovascular drugs might be good for COPD?
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statins
(antiinflammatory effect) |
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What is the score that can estimate 4 year survival for COPD? What are its components?
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BODE
BMI, Obstruction (FEV1), Dyspnea, Exercise (6 minute walk) |
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What is the relation between weight and COPD?
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"The heavier you are, the longer you live"
High risk patients are usually the cachectic ones |
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What is the spirometry criterion for COPD?
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FEV1 / FVC < 70%
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With what spirometry scores should you test ABGs?
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FEV1 < 40% of predicted
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When should you test for alpha-1 antitrypsin insufficiently?
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patients < 45
strong family history |
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Main points of managing STABLE COPD
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smoking cessation
EXERCISE / pulm therapy oxygen therapy if pO2 < 55 or <59 with comorbidities like polycythemia, cor pulmonale) |
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Tiers of therapy for inhalants for COPD
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1. Start with short acting bronchodilators for intermittent sx
2. Add long acting bronchodilator if this isn't enough (LABA like salmeterol, OR anticholinergic like tiotropium) 3. Add inhaled steroid if this doesn't help |
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What is the first inhaler drug usually given to COPD patient?
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tiotropium
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