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29 Cards in this Set

  • Front
  • Back

Griffith

Transformation experiment: bacteria could get trait from other bacteria "transforming" their traits.

Avery, McCarty, MacLeod

Refined Griffiths experiment, proved transforming agent was nucleic acid

Hershey and Chase

"Blender Experiment": proved DNA is hereditary material

Maurice Wilkins and Rosalind Franklin

Used X-rays to study molecular structure. Xray photo of DNA

Watson and Crick

Discovered structure of DNA- Double helix

Erwin Chargaff

All organisms have same bases but in different amounts

AGTC names

Adenine, guanine, thymine, cytosine

Purines

Adenine and Guanine

Pyrimidines

Thymine, cystosine

DNA Ligase

Attaches okazaki fragments

RNA Primer

Joined to parent strand by RNA Primase and eventually replaced with DNA nucleotides

Telomerase

Extends tell me res and can add DNA bases at 5 end.

Point mutations

Single base change

Silent mutation

No amino acid change

Missesense mutation

Amino acid changes- changes final protein

Nonsense mutation

Premature stop codon

Frameshift mutation

Shift in reading frame due to insertion or deletion of base

RNA UACG names

Uracil, adenine, thymine, cytosine

rRNA

Ribosomal rRNA: major component of ribosomes

tRNA

Transfer RNA- carries amino acids to mRNA

mRNA

Messenger RNA- sequence of nucleotides that determines the primary sequence of the polypeptide. Transcription

SnRNA

Small nuclear RNA- forms spliceosomes

siRNA

Small interfering RNA- Targets specific MRNA so it won't be expressed

Promoter Region (TATA box)

Binding site before beginning of gene. Binding site for RNA polymerase and transcription factors

Enhancer region

Binding site for upstream gene and speeds up process

Transcription factors

Bind to promotor región and turn transcription on or off. Triggers binding of RNA polymerase

E-Site

Empty RNA leaves ribosome from exit site

P-site (peptidyl)

Holds tRNA that has polypeptide chain

A-site (aminoacyl)

Holds TRNA carrying next amino acid