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29 Cards in this Set
- Front
- Back
Griffith |
Transformation experiment: bacteria could get trait from other bacteria "transforming" their traits. |
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Avery, McCarty, MacLeod |
Refined Griffiths experiment, proved transforming agent was nucleic acid |
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Hershey and Chase |
"Blender Experiment": proved DNA is hereditary material |
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Maurice Wilkins and Rosalind Franklin |
Used X-rays to study molecular structure. Xray photo of DNA |
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Watson and Crick |
Discovered structure of DNA- Double helix |
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Erwin Chargaff |
All organisms have same bases but in different amounts |
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AGTC names |
Adenine, guanine, thymine, cytosine |
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Purines |
Adenine and Guanine |
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Pyrimidines |
Thymine, cystosine |
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DNA Ligase |
Attaches okazaki fragments |
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RNA Primer |
Joined to parent strand by RNA Primase and eventually replaced with DNA nucleotides |
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Telomerase |
Extends tell me res and can add DNA bases at 5 end. |
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Point mutations |
Single base change |
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Silent mutation |
No amino acid change |
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Missesense mutation |
Amino acid changes- changes final protein |
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Nonsense mutation |
Premature stop codon |
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Frameshift mutation |
Shift in reading frame due to insertion or deletion of base |
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RNA UACG names |
Uracil, adenine, thymine, cytosine |
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rRNA |
Ribosomal rRNA: major component of ribosomes |
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tRNA |
Transfer RNA- carries amino acids to mRNA |
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mRNA |
Messenger RNA- sequence of nucleotides that determines the primary sequence of the polypeptide. Transcription |
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SnRNA |
Small nuclear RNA- forms spliceosomes |
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siRNA |
Small interfering RNA- Targets specific MRNA so it won't be expressed |
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Promoter Region (TATA box) |
Binding site before beginning of gene. Binding site for RNA polymerase and transcription factors |
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Enhancer region |
Binding site for upstream gene and speeds up process |
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Transcription factors |
Bind to promotor región and turn transcription on or off. Triggers binding of RNA polymerase |
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E-Site |
Empty RNA leaves ribosome from exit site |
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P-site (peptidyl) |
Holds tRNA that has polypeptide chain |
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A-site (aminoacyl) |
Holds TRNA carrying next amino acid |