Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
5 Cards in this Set
- Front
- Back
|
What is the pathology of Cushing's?
|
Increased cortisol from a variety of causes
|
|
|
What is the exogenous cause of Cushing's?
|
Steroids, decrease ACTH
Steroids have the same effect as cortisol, so body ACTH decreases because it thinks its already high |
|
|
What is the major endogenous cause of Cushing's?
|
ACTH increase from pituitary adenoma
|
|
|
What are the two minor causes of Cushing's?
|
Ectopic ACTH - from nonpituitary tissues making ACTH
Adrenal - Adenoma, carcinoma, nodular adrenal hyperplasia |
|
|
What are the symptoms of Cushing's?
|
HTN, wt gain, moon facies, truncal obesity, buffalo hump, hyperglycemia, skin changes, osteoporosis, amenorrhea, immune suppression
|
