8/27/2006 Infective Endocarditis

Front 1

Streptococcus viridans (3)

Back 1

1) penicillin 12-18 million units/day divided q4hr x 2wks AND gentamicin 1mg/kg q8hr x 2wks

2)penicillin allergic: ceftriaxone 2gm IV q24hr AND gentamicin 1mg/kg q8hr both x 2wks

3)vancomycin 15mg/kg q12hr x4wks

Front 2

Staph aureus (4)

Back 2

1)Nafcillin 2gm IV q4hr x 4-6wks AND gentamicin 1mg/kg IV q8hr x 3-5days

2)cefazolin 2gm IV q8hr x4-6wks AND gentamicin 1mg/kg IV x 3-5days

3)vancomycin 15mg/kg IV q12h x 4-6wks

4)vancomycin 1gm IV q12hr x 4-6wks

Front 3

Staph epi (2)

Back 3

1)nafcillin 2gm IVPB q4hr AND rifampin 300mg TID for >6wks AND gentamicin 1mg/kg q8hr x 2wks

2)vancomycin 15mg/kg IV q12hr AND rifampin 300mg q8hr for >6wks AND gentamicin 1mg/kg IV q8hr x 2wks

Front 4

Enterococcus
1)high level aminoglycoside resistance
2)penicillin resistant
3)intrinsic penicillin G/ampicillin resistance
4)VRE

Back 4

1)penicillin G or ampicillin IV x8-12wks

2)Unasyn 3gm IV q6hr AND gentamicin 1-1.5mg/kg q8hr IV x 4-6wks
3)vancomycin 15mg/kg IV in 2 divided doses AND gentamicin 1-1.5mg/kg q8hr x 4-6wks

4)Synercid or linezolid

Front 5

HACEK

Back 5

1)ceftriaxone 2gm q24hr x 4wks

2)ampicillin AND gentamicin

Front 6

pseudomonas

Back 6

ceftazidime or zosyn AND aminoglycoside (high dose tobramycin)

Front 7

Candidia or aspergillus

Back 7

amphotericin B 1mg/kg IV daily +/- an azole

Front 8

Prosthetic valve endocarditis (PVE)
a)ealry (<2months)
b)late (>2months post op)

Back 8

a)Vanco 15mg/kg q12h IV AND gentamicin 1mg/kg IV q8hr AND rifampin 600mg PO q24hr

b) same

Front 9

Prophylactic regimens
(dental)

Back 9

1)amoxicillin 2g PO 1hr before procedure

2)clarithromycin or azithromycin 500mg PO 1 hr before procedure

3)clindamycin 600mg PO 1 hr before procedure

Front 10

Prophylactic regimens
(GI/GU procedures)

Back 10

1)ampicillin 2g IV AND gentamicin 1.5mg/kg IV within 30min preop; 6hr later, ampicillin 1g IV, or amoxicillin 1g PO

2)Vancomycin 1g IV AND gentamicin 1.5mg/kg IV within 30 min preop