Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
110 Cards in this Set
- Front
- Back
|
Like other retinoids accutane?
|
…inhibits follicular epidermal keratinization thus loosening the keratin plugs of comedomes and facilitating expulsion, it also reduces the size of the sebaceous glands…
|
|
|
what are some of the rare complications of Vit A deficienc?
|
…corneal perforation Bitots spots, keratomalacia, abnormalities in humoral and CMI immunity…
|
|
|
what does the retina derive from?
|
…the neuroectoderm
|
|
|
thymidine kinase deficient VZV is found almost exclusively in AIDS patients and is best treated with foscarnet a?
|
pyrophosphate analog of DNA polymerase inhibitor that does not require viral kinase activation-
|
|
|
thymidine kinase deficient VZV is found almost exclusively in AIDS patients and is best treated with foscarnet a?
|
pyrophosphate analog of DNA polymerase inhibitor that does not require viral kinase activation-
|
|
|
thymidine kinase deficient VZV is found almost exclusively in AIDS patients and is best treated with foscarnet a?
|
pyrophosphate analog of DNA polymerase inhibitor that does not require viral kinase activation-
|
|
|
describe cidofovir?
|
cidofovir is a broad spectrum antiviral nucleotide analogue of cytosine monophosphate, because cidofovir is already a nucleoside monophosphate its efficacy does not depend upon the prescence of a virally encoded kinase…
|
|
|
mixed connective tissue disease?
|
Anti-SnRP Abs?
|
|
|
mixed connective tissue disease?
|
Anti-SnRP Abs?
|
|
|
…necessary for binding of tRNA to ribosomes, and it contains thymidine, psuedouridine and cytidine residues
|
describe the TYC or T arm of a tRNA?
|
|
|
describe the TYC or T arm of a tRNA?
|
…necessary for binding of tRNA to ribosomes, and it contains thymidine, psuedouridine and cytidine residues
|
|
|
describe the TYC or T arm of a tRNA?
|
…necessary for binding of tRNA to ribosomes, and it contains thymidine, psuedouridine and cytidine residues
|
|
|
what does the D arm of the tRNA have?
|
……diydrouraci residuers…
|
|
|
what does the D arm of the tRNA have?
|
……diydrouraci residuers…
|
|
|
…binds the amino acid specific for that molecule of tRNA it contains the 3’ terminal base residue which binds the amino acid…
|
what is the function of the CCAccpetor stem?
|
|
|
…binds the amino acid specific for that molecule of tRNA it contains the 3’ terminal base residue which binds the amino acid…
|
what is the function of the CCAccpetor stem?
|
|
|
what is the function of the CCAccpetor stem?
|
…binds the amino acid specific for that molecule of tRNA it contains the 3’ terminal base residue which binds the amino acid…
|
|
|
what is the function of the CCAccpetor stem?
|
…binds the amino acid specific for that molecule of tRNA it contains the 3’ terminal base residue which binds the amino acid…
|
|
|
…a whole cm..
|
to be classified as an echymoses how big are u?
|
|
|
to be classified as an echymoses how big are u?
|
…a whole cm..
|
|
|
to be calssified as a petechiae how big are you?
|
…less than 5mm…
|
|
|
to be calssified as a petechiae how big are you?
|
…less than 5mm……less than 5mm…
|
|
|
…less than 5mm…
|
to be calssified as a petechiae how big are you?
|
|
|
hyperplasia of the Stratum corneum?
|
…hyperkeratosis…
|
|
|
sand paper like lesions occurring in sunexposed areas that histologically show hyperkeratosis and parakeratosis and some people consider this SSC insitu?
|
…actinic Keratosis…
|
|
|
where are actinic keratosies?
|
confined to the epidermis
|
|
|
typical appearance if PV?
|
suprabasal blister swith IgG containing deposits in a reticular pattern around keratinocytes the immune target being desmoglein 3…
|
|
|
typical appearance if PV?
|
suprabasal blister swith IgG containing deposits in a reticular pattern around keratinocytes the immune target being desmoglein 3…
|
|
|
typical appearance if PV?
|
suprabasal blister swith IgG containing deposits in a reticular pattern around keratinocytes the immune target being desmoglein 3…
|
|
|
the intestinal and renal absorption of tryptophan is defective, tryptophan is an essential amino acid and a precursur for NAD serotonin and melatonin.
|
what happens in hartnup disease?
|
|
|
what is the main lab finding in hartnups disease?
|
aminoaciduria of neutral amino acids (alanine serine, threonine, valine, leucine isoleucine, phenylalanine, tyrosine, tryptophan and histidine). The urinary excretion of proline, hydroxyproline and arginine remains unchanged and this finding differentiates hartnups from say fanconis
|
|
|
…290-320…
|
UVB waves are the bad ones what give you a sunburn what is there wavelength?
|
|
|
thickening of the epidermis is?
|
acanthosis
|
|
|
thickening of the epidermis is?
|
acanthosis
|
|
|
thickening of the epidermis is?
|
acanthosis
|
|
|
thickening of the stratum Corneum
|
hyperCaratosis is what?
|
|
|
thickening of the stratum Corneum
|
hyperCaratosis is what?
|
|
|
hyperCaratosis is what?
|
thickening of the stratum Corneum
|
|
|
histologically shows dark staining cells with pallisading nuclei?
|
…basal cell carcinoma…
|
|
|
histologically shows dark staining cells with pallisading nuclei?
|
…basal cell carcinoma…
|
|
|
histologically shows dark staining cells with pallisading nuclei?
|
…basal cell carcinoma…
|
|
|
histologically shows dark staining cells with pallisading nuclei?
|
…basal cell carcinoma…
|
|
|
pneumonic for layers of the epidermis?
|
…Colllegiates Love Going on Spring Break
|
|
|
pneumonic for layers of the epidermis?
|
…Colllegiates Love Going on Spring Break
|
|
|
pneumonic for layers of the epidermis?
|
…Colllegiates Love Going on Spring Break
|
|
|
pneumonic for layers of the epidermis?
|
…Colllegiates Love Going on Spring Break
|
|
|
pneumonic for layers of the epidermis?
|
…Colllegiates Love Going on Spring Break
|
|
|
pneumonic for layers of the epidermis?
|
…Colllegiates Love Going on Spring Break
|
|
|
pneumonic for layers of the epidermis?
|
…Colllegiates Love Going on Spring Break
|
|
|
pneumonic for layers of the epidermis?
|
…Colllegiates Love Going on Spring Break
|
|
|
collagen in cartilage, nucleus pulposus, and ocular vitreous, body?
|
…type II…
|
|
|
…type II…
|
collagen in cartilage, nucleus pulposus, and ocular vitreous, body?
|
|
|
nucleuos pulposus collagen?
|
…type II…
|
|
|
collagen of cornea and dentin?
|
…I…
|
|
|
collagen of cornea and dentin?
|
…I…
|
|
|
collagen of cornea and dentin?
|
…I…
|
|
|
collagen of epiphyseal plates
|
…type X…
|
|
|
collagen of epiphyseal plates
|
…type X…
|
|
|
how to calculate likelihood ratio?
|
sensitivity/1-specificity
|
|
|
how to calculate likelihood ratio?
|
sensitivity/1-specificity
|
|
|
how to calculate likelihood ratio?
|
sensitivity/1-specificity
|
|
|
how to calculate likelihood ratio?
|
sensitivity/1-specificity
|
|
|
how to calculate likelihood ratio?
|
sensitivity/1-specificity
|
|
|
a LR greater than 10
|
increases the liklihood that a patient will have a disease for which they are being tested…
|
|
|
what is the pathogenesis of pagets?
|
…the process begins with osteoclastic activation followed by an increase in the activity of bone forming cells- osteoblasts. The end product being a mosaic pattern of lamellar bone with irregular section linked by cement lines which represent areas of bone resorption…
|
|
|
what is the pathogenesis of pagets?
|
…the process begins with osteoclastic activation followed by an increase in the activity of bone forming cells- osteoblasts. The end product being a mosaic pattern of lamellar bone with irregular section linked by cement lines which represent areas of bone resorption…
|
|
|
what is the pathogenesis of pagets?
|
…the process begins with osteoclastic activation followed by an increase in the activity of bone forming cells- osteoblasts. The end product being a mosaic pattern of lamellar bone with irregular section linked by cement lines which represent areas of bone resorption…
|
|
|
what is the pathogenesis of pagets?
|
…the process begins with osteoclastic activation followed by an increase in the activity of bone forming cells- osteoblasts. The end product being a mosaic pattern of lamellar bone with irregular section linked by cement lines which represent areas of bone resorption…
|
|
|
bipolar I?
|
history of at least one manic episode with or without major depression…
|
|
|
bipolar II?
|
…one major depressive episode and one hypomanic episode…
|
|
|
…a low intensity mood disturbance lasting at least two years…
|
dysthima is?
|
|
|
what are the Sx of congenital hypothyroidism?
|
lethargy, poor feeding, prolonged jaundice, demonstrate constipation, muscle hypotonia and a hoarse cry…
|
|
|
what are the Sx of congenital hypothyroidism?
|
lethargy, poor feeding, prolonged jaundice, demonstrate constipation, muscle hypotonia and a hoarse cry…
|
|
|
what are the Sx of congenital hypothyroidism?
|
lethargy, poor feeding, prolonged jaundice, demonstrate constipation, muscle hypotonia and a hoarse cry…
|
|
|
what are the Sx of congenital hypothyroidism?
|
lethargy, poor feeding, prolonged jaundice, demonstrate constipation, muscle hypotonia and a hoarse cry…
|
|
|
as dislocation of lens
…CV abnormalities including ascending aortic aneurysm, dissection and MVProlapse |
what are the three prominent features of marfans?
|
|
|
as dislocation of lens
…CV abnormalities including ascending aortic aneurysm, dissection and MVProlapse |
what are the three prominent features of marfans?
|
|
|
what are the three prominent features of marfans?
|
…CV abnormalities including ascending aortic aneurysm, dissection and MVProlapse
|
|
|
what is the cause of osteopetrosis?
|
…impaired osteoclastic bone resorption and is characterized by increased bone thickness and density, it is important to not that in this disease osteoblasts in patients function normally…
|
|
|
what is the cause of osteopetrosis?
|
…impaired osteoclastic bone resorption and is characterized by increased bone thickness and density, it is important to not that in this disease osteoblasts in patients function normally…
|
|
|
what is the cause of osteopetrosis?
|
…impaired osteoclastic bone resorption and is characterized by increased bone thickness and density, it is important to not that in this disease osteoblasts in patients function normally…
|
|
|
what is the cause of osteopetrosis?
|
…impaired osteoclastic bone resorption and is characterized by increased bone thickness and density, it is important to not that in this disease osteoblasts in patients function normally…
|
|
|
…impaired osteoclastic bone resorption and is characterized by increased bone thickness and density, it is important to not that in this disease osteoblasts in patients function normally…
|
what is the cause of osteopetrosis?
|
|
|
The differentiation of osteoclasts is mainly governed by?
|
RANK-ligand and by monocyte colony stimulating factor, bothe of which are produced by osteoBLASTS…
|
|
|
The differentiation of osteoclasts is mainly governed by?
|
RANK-ligand and by monocyte colony stimulating factor, bothe of which are produced by osteoBLASTS…
|
|
|
…weeks or months later, there may be CNS and or cardiac involvement such as bell’s palsy or AV nodal block…
|
describe the second phase of lyme disease after eryhtema chronica migrans?
|
|
|
describe the second phase of lyme disease after eryhtema chronica migrans?
|
…weeks or months later, there may be CNS and or cardiac involvement such as bell’s palsy or AV nodal block…
|
|
|
describe the second phase of lyme disease after eryhtema chronica migrans?
|
…weeks or months later, there may be CNS and or cardiac involvement such as bell’s palsy or AV nodal block…
|
|
|
the inferior parathyroid gland originates from?
|
…the 3rd pharyngeal pouch just like the thymus…
|
|
|
… the first pharyngeal pouch
|
the epithelium of the middle ear and auditory tube originates from what?
|
|
|
name two uricouric drugs?
|
probenecid and sulfinpyraZONE…
|
|
|
name two uricouric drugs?
|
probenecid and sulfinpyraZONE…
|
|
|
a new xanthine oxidase inhibitor that is thought to be safer in patients with renal dysfunction and has fewer interactions compared to allopurinol
|
zfebuxostat is what
|
|
|
a new xanthine oxidase inhibitor that is thought to be safer in patients with renal dysfunction and has fewer interactions compared to allopurinol
|
zfebuxostat is what
|
|
|
During Muscle contraction calcium is released from the SR in addition to binding troponin C and activating muscle contraction calcium activates?
|
myophosphorylase (muscle glycogen phosphorylase) to cause breakdown of glycogen and release glucose-1 phosphate which is converted to glucose-6phosphate by an enzyme called phosphoglucomutase…
|
|
|
During Muscle contraction calcium is released from the SR in addition to binding troponin C and activating muscle contraction calcium activates?
|
myophosphorylase (muscle glycogen phosphorylase) to cause breakdown of glycogen and release glucose-1 phosphate which is converted to glucose-6phosphate by an enzyme called phosphoglucomutase…
|
|
|
During Muscle contraction calcium is released from the SR in addition to binding troponin C and activating muscle contraction calcium activates?
|
myophosphorylase (muscle glycogen phosphorylase) to cause breakdown of glycogen and release glucose-1 phosphate which is converted to glucose-6phosphate by an enzyme called phosphoglucomutase…
|
|
|
Glucagon and epinephrine act on G-protiens in the liver to ?
|
causing cleavage of ATP froming camp which in turn stimulates protein kinase A. which can phosphorylate glycogen phosphorylase leading to inactivation where as phosphorylation of glycogen synthase leads to its inactivation
|
|
|
Glucagon and epinephrine act on G-protiens in the liver to ?
|
causing cleavage of ATP froming camp which in turn stimulates protein kinase A. which can phosphorylate glycogen phosphorylase leading to inactivation where as phosphorylation of glycogen synthase leads to its inactivation
|
|
|
Glucagon and epinephrine act on G-protiens in the liver to ?
|
causing cleavage of ATP froming camp which in turn stimulates protein kinase A. which can phosphorylate glycogen phosphorylase leading to inactivation where as phosphorylation of glycogen synthase leads to its inactivation
|
|
|
homogentisate is derived from?
|
…tyrosine which is derived from phenylalanine…
|
|
|
homogentisate is derived from?
|
…tyrosine which is derived from phenylalanine…
|
|
|
homogentisate is derived from?
|
…tyrosine which is derived from phenylalanine…
|
|
|
homogentisate is derived from?
|
…tyrosine which is derived from phenylalanine…
|
|
|
what is the pathway of phenylalanine to fumarate?
|
phenylalanine to tyrosine via its hydroxylase, tyrosine to homogentisate and homogentisate to maleylacetoacetate, amd maleylacetoacetate to Fumarylacetoacetate to fumarate in the TCA (which just so happens to be made by fucking succD)
|
|
|
what is the pathway of phenylalanine to fumarate?
|
phenylalanine to tyrosine via its hydroxylase, tyrosine to homogentisate and homogentisate to maleylacetoacetate, amd maleylacetoacetate to Fumarylacetoacetate to fumarate in the TCA (which just so happens to be made by fucking succD)
|
|
|
what is the pathway of phenylalanine to fumarate?
|
phenylalanine to tyrosine via its hydroxylase, tyrosine to homogentisate and homogentisate to maleylacetoacetate, amd maleylacetoacetate to Fumarylacetoacetate to fumarate in the TCA (which just so happens to be made by fucking succD)
|
|
|
zona occludens is a
|
tight junction
|
|
|
zona occludens is a
|
tight junction
|
|
|
A high PTH with a low or normal calcium reflects what?
|
renal failure or D deficiency…
|
