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24 Cards in this Set

  • Front
  • Back
epidemiologic triad of disease
host, environment, agent (vector)
types of host-agent interactions
1) infectivity
2) virulence
3) immunogenicity
4) pathogenicity
pathogenic mechanisms (not important)
1) direct tissue invasion
2) production of toxin
3) immunologic enhancement or allergy
4) persistent or latent infxn
5) enhanced susceptibility to drugs
6) immune suppression
how can humans act as reservoirs?
can be cases or carriers
mechanisms of transmission?
1) direct
2) indirect
a. vehicle borne
b. vector borne
c. airborne
EKC via tonometer probe.

mode of transmission?
vehicle borne
malaria

mode of transmission?
vector borne
TB

mode of transmission?
airborne

(inhalation of aerosolized bacteria)
SARS

mode of transmission?
airborne
what does herd immunity determine?
whether or not an organism will be successful in creating an epidemic
how can you transmit disease in an exam room?
1) tears/ocular secretions
2) coughing/sneezing
3) blood
proportion of the world that is infected with TB
1/3
how many people in the world have active TB?
20 mil
# of new cases of TB per year?
8 mil
how many people die each year from TB?
2-3 mil
1) TB incidence in the US __ from 1953 to 1984.
2) what happened in 1985?
1) decreased
2) the trend reversed
TB in the US: __ per 100,000
4.2
where is TB most incident?

least?
in the most populated states (CA, TX, NY, FL)

north dakota, etc
genetic/health risk factors of TB?
1) diabetes
2) silicosis
3) gastrecotomy
4) malnutrition
5) alcholism
6) hematologic disorders
7) malignancies
8) immunosuppression
you're more likely to have TB if you...
have HIV/AIDS or are homeless (socioeconomic factors)

are male (2x more likely)
TB is found in __
dark, poorly ventilated areas
how likely are you to have TB within your lifetime?
10%
how likely are you to have active TB within 1 year?
5%
how can u prevent TB?
1) ventilation
2) filters (HEPA)
3) screening