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31 Cards in this Set

  • Front
  • Back
What's the placenta?

connects mom and fetus

What does the placenta do?


bring nutrients to the fetus




Forms from trophoblasts (8wks)




gas exchange




excretes fecal waste products into maternal blood




Maternal recognition of pregnancy




Alters immune environment (down regulates so you don't reject)




Alters maternal cardiovascular and metabolic functions through hormones.



Placenta is the 1st fetal organ made from trophoblast (how long into fertilization)

8 wks
The umbilical cord


connects baby to placenta




vein is o2 rich


artery is o2 poor

Capacity of placenta depends on the fetus


200 ml blood exchanged per min


Uses 30-40% of glucose from maternal circ


Can accumulate glycogen


Regulate maternal physiology in favor of fetus (not a parasite, though) .

Successful pregnancy


full term (37 wks)


infant birth weight of 7 lbs 12 oz


Appropriate for GA

Increase mortality and morbidity of pregnancy


preterm


very preterm


LBW


VLWB


what is a preterm baby

before 37 weeks

very preterm baby/

<35 wks

LBW baby

5 lbs 8 oz

VLBW baby

5 lbs 3 oz


Small for gestational age categories:



Disproportional


Proportional


Macrosonic


Disproportional


head circumference and length are normal, but weight is <10th


Better because length and head are better off




you want your baby to be disproportional if LBW.

Proportional

Head, length, and wt are all in <10th percentile

Macrosonic


>10 lbs


90th%


gestational diabetes

Trend in infant mortality rate over the past 20 years


Decrease in infant mortality rate


- across all countries.




Sharp decrease in 1910 with increased sanitation.

US and infant mortality

US is ranked 34th in infant mortality



we can carry our babies to term and make them live longer postnatal.




aren't just characterized as "stillbirths"

Worldwide and infant mortality


Africa highest in mortality (steep downward slope)




Europe the lowest




decline overall

Stages from ovulation to implantation


ovulation


fertilization/conception


zygote


day 1-5


day 6-12 (implantation)

Ovulation


ovum gets released from fallopian tube, goes to uterus




24 hours

Fertilization/conception


sperm meets egg


sperm cell life is 48-72 hrs

Zygote


chromosomal material fuses together




Goes to body of uterus (3-4 days)




Mortulation: cells divide (every 24 hrs, 16-50 cells)




Blastocyst: morula floats for 3-4 days, still dividing


- large cells will cluster around periphery and fluid filled area will start to form.




READY FOR SOME IMPLANTATION

Days 1-5


Cells will divide to mortula


eventually becomes a blastocyst

Days 6-12

IMPLANTATION




Blastocyst embeds into the uterine wall - secrete enzymes that will eat through hit.




Cells on inner are embryonic stem cells.




Needs nutrients for implantation (antioxidants)




Once implanted - protected by uterine wall






YOLK sac: vital for survival until placenta forms.



yolk sac
a structure that provides nutrients from the mother to the embryo before the placenta is ready to function.

Importance of proper implantation


if you don't have it, what happens?


the fetus will not survive
How to ensure proper implanation
good nutrition/overall health (adequate wt, exercise daily, diet rich in whole grains, fruits veg), no unhealthy habits (smoking drinking, etc)

feto-uterine connection

if you don't have this there's no way the pregnancy will survive because there's nothing attaching the fetus to the mother.
proper implantation and nourishing the early embryo


accommodates growth and differentiation of the developing fetus






uterus is of fundamental importance to reproduction - it nourishes the early embryo and accommodates growth and differentiation of the developing fetus.

0-2 months major events


CNS if very vulnerable during this time


major organ development


2-3 weeks major events


cells are specialized




brain and spinal cord begin developing


cardio systems begin forming




neural tube (3 layers): ectoderm is the top (skin), mesoderm, and endoderm (tube, internal organs)