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16 Cards in this Set
- Front
- Back
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What is the general mechanism for Cephalosporins?
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Inhibit cell wall synthesis
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Which four organisms are not covered by cephalosporins?
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LAME
Listeria Atypicals - chlamydia, mycoplasma MRSA (except ceftaroline) Enterococci |
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Which things do 1st gen and 2nd gen Cephalosporins fight?
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G+ cocci
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Which two drugs are 1st gen Cephalosporins?
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Cefazolin
Cephalexin |
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What three things do 1st gen Cephalosporins fight?
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PEcK
Proteus E Coli Klebsiella Pneumoniae |
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What is the route of use for 1st gen Cephalos?
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Cefazolin - IV/IM
Cephalexin - Oral |
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Which three drugs are 2nd gen Cephalosporins?
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Cefoxitin
Cefaclor Cefuroxime |
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What is the route of use for 2nd gen cephalos?
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Cefoxitin - IM/IV
Cefaclor - Oral Cefuroxime - IM/IV |
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What seven things do 2nd gen Cephalosporins fight?
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HEN PEcKS
Haemophilus Influenzae Enterobacter Aerogenes Neisseria spp Proteus Mirabilis E Coli Klebsiella Pneumoniae Serratia Marcescens |
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Which three drugs are 3rd gen Cephalosporins?
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Ceftriaxone
Cefotaxime Ceftazidime |
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What do 3rd gen Cephalosporins fight?
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Serious G- infections
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What specifically does Ceftriaxone fight?
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Meningitis and Gonorrhea
CAP - Community acquired pnemo |
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Which three 3rd gen cephalos are antipseudomonal?
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Ceftizoxime
Cefoperazone Ceftazidime |
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What is the 4th gen Cephalosporin?
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Cefepime
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What does cefepime fight?
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Pseudomonas and G+ orgs
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Why is cefepime used in place of 3rd gen cephalos?
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More resistant to b-lactamases
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