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61 Cards in this Set
- Front
- Back
Elie Metchnikoff
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Founded phagocytosis
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Paul Ehrilich & Emil von Behring
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Humoral immunity. Immulity to diptheria and tetanus resided in the cell free portion of the blood.
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Wright and Douglas
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Who discovered Opsonins: serum substances aided phagocytosis?
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microorganisms
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What causes infectious diseases?
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Disease
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Any abnormality of body structure and/or function.
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Infection disease
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Diesease caused by microorganisms.
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Infection
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The invasion or colonization of the body by a pathogenic microorganism.
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Symbiosis
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living together
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Commensalism
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One organism is benefited and the other is unaffected.
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Mutualism
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Both organisms are benefited.
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Parasitism
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One organism is benefited at the expense of the other. (when the host is harmed)
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Host-microbial relationships
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Transient Microbiota/Flora
Normal/resident microbiota/flora Opportunist/opportunistic pathogen Pathogens |
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Transient Microbiota/Flora
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Present only for a short time, without causing disease.
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Opportunist/opportunistic pathogen
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Organisms which are potentially disease causing but don't cause disease in healthy individuals. May cause disease in: immune compromised or suppreseed individuals, antibiotic therapy, ectopic sites (not normal place found), etc.
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Pathogens
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Disease causing organisms.
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Normal/resident microbiota/flora
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Microorganisms that colonize the body without causing disease.
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Microbial antagonism
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Prevents overgrowth of invading organisms/pathogens.
good guys help prevent disease |
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symptom
sign syndrome communicable disease contagious noncommunicable disease |
What are the classifications of infectious disease? (6)
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symptom
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subjective
something that someone feels |
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sign
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Objective
Can be observed and measured Something you see |
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syndrome
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A group of symptoms/signs that together characterize a specific condition/disease.
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communicable disease
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Any disease spread from one host to another
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contagious
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Easily spread from one person to another.
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Noncommunicable disease
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1. opportunist
2. organism resides outside the body and is introduced by mechanical means. e.g. Clost tetani (tetanus) |
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clost tetani (tetanus)
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Give me an example of a noncommunicable disease.
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incidence of disease
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morbidity rate
# of new cases over a certain time period per healthy pop. Usually given as # of cases/100,000. |
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Prevalance
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___________ of a disease is the percent of the population having a particular disease at any given time.
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incidence
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The _________ of a disease is the fraction of a population that contracts it during a particular length of time.
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sporadic
endemic |
If a disease occurs only occationally, it is termed _________; when it is constantly present, as is the common cold, it is termed ________.
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acute
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An ______ disease is one that develps reapidly but last only a short time.
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chronic
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A ______ disease develops more slowly and the body reactions are often less severe, but its continuous or recurrent for long periods of time.
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subacute
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Diseases intermediate btwn acute and chronic are described as ________.
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latent
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A _______ disease is one in which the pathogen is inactive for a time but then becomes active to produce the symptoms
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Local infection
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is one in which the invading microorganisms are limited to a relatively small area of the body, e.g., boils.
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Systemic or generalized –
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infection, microorganisms or their products are spread throughout the body by the blood or lymphatic system
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Focal infection
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one in which a local infection, sinuses, enters the blood or lymph and spreads to other parts of the body.
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The presence of bacteria in the blood
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Bacteremia –
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Sepsis
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a toxic inflammatory condition arising from the spread of bacteria or baterial toxins from a focus of infection
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Septicemia
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sepsis that results from the proliferation of bacterial pathogens in the bloodstream
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presence of toxins in the blood.
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Toxemia –
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Viremia –
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presence of viruses in the blood.
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– is an acute infection that causes the initial illness.
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Primary infection
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Secondary infection
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caused by an opportunist only after the primary infection has weakened the body’s defenses.
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Subclinical (inapparent) infection
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one that does not cause any noticeable illness.
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Predispoing factors
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_________ _______, such as gender, genetic background, climate, age, and nutrition, can greatly affent the occurrence of disease in individuals
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Incubation period
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the time btwn actual infection and the first appearance of signs or symptoms.
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Prodromal period.
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follow the incubation period in some diseases and is characterized by mild symptoms of the disease
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Period of illness
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The overt symptoms of the disease are apparent.
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Period of decline .
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The signs and symptoms subside
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period of convalescence
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The patient regains his or her prediseased state
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Incubation period
Prodromal period Period of illness Period of decline Period of convalescence |
What are the 5 developments of disease?
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reservior of infection
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A continual source of the pathogen, such as an animal or inanimate object.
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direct contact transmission
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Infections may be spread more or less directly from one host to another by, ______ ______ ___________, such as kissing, handshaking, bites, or sexual intercourse.
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Droplet infection
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Agents of the disease are spread very short distances(less than meter) while contained in droplets of saliva or mucus from coughing or sneezing.
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indirect contact transmission
fomite |
_______ ______ __________ involves a nonliving object, such as a drinking cup or towel, called a _______.
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vehicle transmission
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_______ __________ is inanimate reserviors such as food, water, or blood may transmit diseases to large numbers of individuals.
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airborne transmission
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Diseases spread by agents of infection traveling on droplets or dust for a distance of more than a meter are considered to occur by ______ _________.
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vectors
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animals that carry pathogens from one host to another.
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Mechanical transmission
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Insects carry pathogens on their bodies to food that is later swallowed by the host.
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Biological transmission
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The anthropod may pass the pathogen in a bit, or it may pass the pathogen in its feces, which later enter the wound caused by the anthropods bite.
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Portals of exit
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Routes by which a pathogen leaves the body
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