3 Ch 39, 40, 42 (Quiz 3)

Front 1

What will GC do in relation to stress?

Back 1

Inc: gluconeogenesis
glycogen synthesis
BG
catbolism (breakdown)

Front 2

How are GC anti-inflammatory?

Back 2

Dec. leukocytes, cytokine, chemokines, macrophage and COX II expression

Front 3

Long duration GC

Back 3

Betamethasone
Dexamethasone

Front 4

2 MC

Back 4

fludrocortisone
desoxycorticosterone

Front 5

Chronic AC insufficiency

Back 5

Addison's disease

Front 6

Treatment for Addisons or congenital adrenal hyperplasia

Back 6

hydrocortisone (GC)
fludrocortison (MC)

Front 7

What is the treatment for Cushings

Back 7

surgery
irradiation
large dose cortisol->reduced dose

Front 8

Treatment for aldosteronism

Back 8

Spironolactone

Front 9

What can be given IM maternall to inc. fetal lung maturation

Back 9

betamethasone

Front 10

What kind of diet should someone with GC toxicity be on?

Back 10

high protein
high potassium

Front 11

GC are contraindicated in what populations?

Back 11

PUD heart disease
CHF Infxn
Psych DM
Osteo glaucoma

Front 12

Precursor to aldosterone

Back 12

deoxycorticosterone

Front 13

Most commonly used MC

Back 13

fludrocortisone

Front 14

Drugs that inhibits synthesis of cortisol and used to test adrenal fxn

Back 14

Metyrapone

Front 15

Antifungal that inhibits adrenal and gonadal steroid

Back 15

ketoconazole

Front 16

Anti-progestin and GC, will reverse cushingoid effects

Back 16

Mifepristone (RU486)

Front 17

Competes with aldosterone sites

Back 17

Spironolactone

Front 18

Aldosterone antoagonist used to treat HTN

Back 18

Eplerenone

Front 19

3 endogenous estrogens

Back 19

estradiol
estrone
estriol

Front 20

4 estrogens, not estradiols

Back 20

DES
Quinestrerol
Chlorotrianisene
Methallenestril

Front 21

2 clinical uses of estrogen

Back 21

1* hypogonadism
ERT

Front 22

If woman had hysterectomy-how do you prescibe HRT?

Back 22

can use estrogen alone

Front 23

What kind of cancer does progestin prevent

Back 23

Endometrial

Front 24

Where is progesterone synthesized

Back 24

ovary
testes
adrenals
placenta

Front 25

Effects of progesterone

Back 25

Inc. lipoprotein lipase -> inc. fat deposition

maturation of endometrium after ovulation

Front 26

Competitive partial estrogen agonist used to treat breast Ca post menopause

Back 26

tamoxifen

Front 27

Partial estrogen agonist prevent post menopausal osteroporosis

Back 27

raloxifene

Front 28

Partial estrogen agonist that induces ovulation

Back 28

Clomiphene

Front 29

Weak progestin, androgen, & GC suppresses ovaries

Back 29

Danazol

Front 30

Testosterone is converted to dihydrotestosterone by what?

Back 30

5 alpha reductase

Front 31

Drug that inhibits 5 alpha reductase-used for BPH, male pattern baldness, hirsutism

Back 31

Finasteride

Front 32

4 Androgen RH analogs

Back 32

Goserelin
nafarelin
Buserelin
Leuprolide

Front 33

Drug used to treat excessive libido, female hirutism

Back 33

Cyproterone

Front 34

Sub Q rDNA PTH used to treat osteoporosis

Back 34

Teriparatide

Front 35

Vit D first hydroxylated in the liver to form

Back 35

Calcifediol

Front 36

25 OH vit. D further converted in the kidney to

Back 36

Calcitriol

Front 37

Hormone secreted by thyroid to decrease calcium concentration

Back 37

Calcitonin

Front 38

How do GC effect calcium?

Back 38

Antag. Vit. D intestinal transport by stim. renal excretion of Ca++

Front 39

Group of drugs that inhibit bone resorption. Treat Paget's and osteoporosis

Back 39

Biphosphonates
Etidronate
Pamidronate
Alendronate
Risedronate
Tiludronate
Zoledronate

Front 40

s/s hypocalcemia

Back 40

tetany
laryngospasm
muscle cramps
convulsions

Front 41

Drug that protects against spine fractures, but not hip

Back 41

Raloxifene