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14 Cards in this Set
- Front
- Back
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5 alterations that NSAIDs are useful in treating
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- Inflammation
- Endotoxemia - Pain - Fever - Hypercoagulability |
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How do NSAIDs reduce fever?
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Reduce production of PGE2, which acts on hypothalamus to induce fever
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How do NSAIDs reduce coagulability?
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Reduces production of thromboxane
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3 toxicities common to NSAIDs
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- GI
- Renal - Hematopoietic |
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NSAID CI in cats
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Aceteminophen
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2 NSAIDs that are CI in dogs
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- Ibuprofen
- Phenylbutazone |
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Aspirin
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COX - 1: ++++
COX - 2: - |
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Phenylbutazone
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COX - 1: ++++
COX - 2: - |
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Flunixin
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COX - 1: +++
COX - 2: + |
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Ketoprofen
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COX - 1: +++
COX - 2: + |
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Diclofenac
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COX - 1: ++
COX - 2: ++ |
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Carprofen
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COX - 1: +
COX - 2: +++ |
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Meloxicam
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COX - 1: +
COX - 2: +++ |
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What's the only NSAID approved for cats?
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Meloxicam
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