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14 Cards in this Set
- Front
- Back
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What is the toxin and manifestation of Corynebacterium Diptheriae?
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Diptheria Toxin = Pharyngitis w/ Pseudomembranes in throat w/ bull neck
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What is the toxin and manifestation of P. Aeruginosa?
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Exotoxin A = host cell death
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What is the toxin and manifestation of Shigella spp?
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Shiga Toxin = GI damage --> dysentery
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What is the toxin and manifestation of Enterohemorrhagic E. Coli?
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Shiga-like toxin = hemolytic uremic syndrome
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What is the toxin and manifestation of Enterotoxigenic E. Coli?
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Heat labile toxin = watery diarrhea (labile in the air)
Heat stable toxin = watery diarrhea (stable on ground) |
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What is the difference between Heat labile and Heat Stable versions of ETEC?
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HL - Inc Cl secretion in gut, leading to inc H20 efflux
HS - Dec resorption of NaCl and H20 in gut |
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What is the toxin and manifestation of Bacillus Anthracis?
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Edema Factor = edematous black eschars
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What is the toxin and manifestation of Vibrio Cholerae?
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Cholera toxin = Inc Cl secretion into gut leading to H20 efflux
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What is the toxin and manifestation of Bordetella Pertussis?
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Pertussis toxin = disables Gi, impairs phagocytosis --> whooping cough
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What is the toxin and manifestation of Clostridium Tetani?
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Tetanospasmin = prevent release of inhibitory GABA and Glycine = Muscle rigidity
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What is the toxin and manifestation of Clostridium Botulinum?
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Botulism Toxin = prevent release of stimulatory ACh signals = Flaccid paralysis
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What is the toxin and manifestation of Clostridium Perfringens?
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Alpha toxin = degredation of tissue and cell membranes = myonecrosis + hemolysis
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What are the 2 toxins and manifestations of Strep Pyogenes?
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Streptolysin O = degradation of cell membrane = hemolysis
Exotoxin A = Toxic Shock Syndrome |
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What is the toxin and manifestation of S. Aureus?
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Toxic Shock Syndrome Toxin 1 = overwhelming release of IFN-y and IL-2 --> shock, scalded skin syndrome, food poisoning
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