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5 Cards in this Set
- Front
- Back
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PPP accomplishes two goals. What are they?
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1. Generate 5C from 6C moeity
2. Create NADPH for reductive biosynthesis |
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What is the rate-limiting step in PPP?
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Glucose-6-P-dehydrogenase
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Which carbon is decarboxylated in PPP?
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C1.
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What two antioxidant systems require NADPH?
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1. glutathione synthase
2. cytochrome p450 (detox) |
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What form of glutathione is needed to react with ROS - oxidized or reduced?
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reduced. GSH is a tripeptide with a free sulfhydrl group, used by glutation peroxidase to safely remove H2O2.
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