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65 Cards in this Set

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m/c location is coccygeal junction
Chordoma
2nd most common location is spheno-occipital region (clivus)
Chordoma
m/c location is coccygeal junction
Chordoma
2nd most common location is spheno-occipital region (clivus)
Chordoma
3rd m/c location is C2
Chordoma
Tumor of notochordal origin
Chordoma
Ages 40-70 and m/c in males
Chordoma
GCT is a DDx, especially in the sacrum
Chordoma
The presacral area (aka retrorectal space) should be less than 2cm. If it's bigger, this could be there
Chordoma
Aggressive, destructive lesion of sacrum
GCT
Chondrosarcoma
chordoma
secondary lesion to metastasis
Aggressive, destructive lesion of sacrum
GCT
Chondrosarcoma
chordoma
secondary lesion to metastasis
Aggressive, destructive lesion of sacrum
GCT
Chondrosarcoma
chordoma
secondary lesion to metastasis
Aggressive, destructive lesion of sacrum
GCT
Chondrosarcoma
chordoma
secondary lesion to metastasis
Aggressive, destructive lesion of sacrum - slow growing, can cross disc space
Chordoma
Area of joint with ny synovia and no cartilage
Bare area
Aggressive, destructive lesion of sacrum
GCT
Chondrosarcoma
chordoma
secondary lesion to metastasis
Aggressive, destructive lesion of sacrum
GCT
Chondrosarcoma
chordoma
secondary lesion to metastasis
Aggressive, destructive lesion of sacrum
GCT
Chondrosarcoma
chordoma
secondary lesion to metastasis
Aggressive, destructive lesion of sacrum
GCT
Chondrosarcoma
chordoma
secondary lesion to metastasis
Aggressive, destructive lesion of sacrum - slow growing, can cross disc space
Chordoma
Area of joint with ny synovia and no cartilage
Bare area
Erosion in bare area of joint
Psoriatic Arthritis
Joint space loss
Psoriatic Arthritis
Distal cocktail sausages
Psoriatic Arthritis
bilateral involvement (arthritis)
Psoriatic Arthritis
bamboo spine
ankylosing spondylitis
Erosion in bare area of joint
Psoriatic Arthritis
Joint space loss
Psoriatic Arthritis
Distal cocktail sausages
Psoriatic Arthritis
bilateral involvement (arthritis)
Psoriatic Arthritis
bamboo spine
ankylosing spondylitis
75% are 40-70 year olds
Multiple Myeloma
females
Multiple Myeloma
disseminated pattern
Multiple Myeloma
plasmacytoma patern
Multiple Myeloma
Raindrop Skull
Multiple Myeloma
Swiss Cheese appearance on skull
Lytic Mets
Punched out lesions in long bone
Multiple Myeloma
Osteoblasts are inhibited, so it' s NOT sclerotic. There is also indirect activation of osteaclasts (to do with RANKL.)
Multiple Myeloma
Immunoglobulins, especially IgG (55%)
Multiple Myeloma
aka Kahler's Disease
Multiple Myeloma
m/c primary malignant tumor of bone
Multiple Myeloma
Plasma cell dyscarasia (no pathaogen, so no reason for it)
Multiple Myeloma
Found in skull
Multiple Myeloma
Found in spine
Multiple Myeloma
Found in ilia
Multiple Myeloma
Fanconi's syndrome
Multiple Myeloma
97% percent of people who get plasmocytoma will get this
Multiple Myeloma
Bone scan may be cold (no color at all)
Multiple Myeloma
cortex, scalloping erosions are classic
Multiple Myeloma
MRI is best for this
Multiple Myeloma
Bence Jones protein uria is pathagnomic
Multiple Myeloma
Reasons for death: 1- pneumonia due to infection; 2-renal failure
Multiple Myeloma
CRAB
Multiple Myeloma
CRAB - the C
hyperCalcemia of Multiple Myeloma
CRAB - the R
Renal failure - Multiple Myeloma
CRAB - the A
Anemia and amyloidosis
CRAB - the B
Bone lesion and pain - punched out lesions
Lytic destruction over 40
1-lytic metastasis
2-Multiple Myeloma
3-lymphoma
Lytic destruction over 40
1-lytic metastasis
2-Multiple Myeloma
3-lymphoma
Lytic destruction over 40
1-lytic metastasis
2-Multiple Myeloma
3-lymphoma
Electrophoresis M Spike
Multiple Myeloma
A:G reversed
Multiple Myeloma
m/c benign tumor of bone
Fibrous Dysplasia
Can be monostotic, polyostotic, polostotic with endocrine dysfunction
Fibrous Dysplasia