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313 Cards in this Set
- Front
- Back
myofibre
|
myotube in development
|
|
myocyte
|
myoblast in development
cell in muscle |
|
location of actin and myosin?
|
cytoplasm
|
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3 types of muscle
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skeletal, cardiac, smooth
*tendons are continuous with the outer coating |
|
epimysium
|
the whole skeletal muscle is wrapped in this
(outside layer?) |
|
fascicle
|
a small bundle of muscle or nerve fibers
bound together by connective tissue outermost layer of skeletal muscle |
|
perimysium
|
connective tissue that groups fibers into a fascicle
'middle layer of skeletal muscle' |
|
endomysium
|
inner most layer of skeletal muscle
binds muscle fibers together to form a fascicle |
|
characteristics of skeletal muscle fibers (4)
|
1. large (.1-.5 mm diameter, 1cm++length)
2) multinucleate (100s of nuclei) 3) peripheraly located nuclei 4) striated **cells fuse together and make one multinucleated cell |
|
syncytium
|
multiple cells coming together and maintaining nuclei
-skeletal muscle |
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where is the sarcomeric organization of muscle fibers in a cell?
|
cytoplasm
-cytoplasm has parallel striations from top to bottom |
|
A band
|
anisotropic
|
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I band
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isotropic
|
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M line
|
thin line down the muscle
-extra proteins down middle of M line |
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sarcomere
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basic contractile unit of piece of muscle
|
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Z line
|
form left and right hand edge of one sarcomere
|
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where is the thin actin filament attached to?
|
Z line
|
|
sliding filament hypothesis
|
sucker walk along actin and the myosin moves
ATP hydrolysis causes flexing of cross-bridges |
|
motor end plate
|
end plate where all the synapses are
motor bc muscle motor neurons |
|
how many muscle fibers can one motor neuron innervate?
|
a few to thousands
|
|
what is the stimulus for a skeletal muscle to contract?
|
motor neuron
|
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T-tubule
|
channel system in skeletal muscle
signal down from outside and traverses to cysteinine? |
|
triad
|
skeletal muscle
T-tubule channel system is at every sarcomere, and is the recipient |
|
action potentials in sarcomeres
|
action potential from the end plate gets to every sarcomere in T-tubule syste, Ca releases, acts on actin to allow cross-bridges
vessicles are the receptors telling you to fire action potential |
|
ATP for contractions from??
|
mitochondria
|
|
damaged skeletal muscle
|
bust open cell and all myofibrils bust out
cell can never recover |
|
satellite cells
|
for regeneration and repair
"stem cells of muscles" divide and replace dead myofibers |
|
organization of muscles (skeletal)
|
epimysium-tendon-perimysium (inner)
usually arranged in antagonistic groups of flexors and extensors |
|
muscle origin
|
origin is proximal
origin doesn't move top of muscle; where attaches |
|
muscle insertion
|
insertion is distal
insertion usually moves bottom of muscle |
|
isotonic
|
shortening of muscle against constant load
mode of contraction |
|
isometric
|
mode of contraction
tension develops but little movement constant load but no movement |
|
flexion
|
movement that brings a distal limb segment toward the next proximal segment, advances a limb at the shoulder or hip, or bends the head or a part of the trunk toward the midventral line
opposite of extension eg elbow, hand |
|
extension
|
movement that carries a distal limb segment away from the next proximal segment, retracts a limb at the shoulder or hip, or moves the head or a part of the trunk toward the mid-dorsal line
opposite of flexion eg, elbow, hand |
|
protraction
|
muscle contraction that moves the entire appendage of a quadruped forward
opposite of retraction eg shoulder, thigh (take a step) |
|
retraction
|
action that moves the entire appendage of a quadruped backward
opposite of protraction eg shoulder, thigh |
|
adduction
|
moves a structure toward the midventral line of the body
eg leg ADD |
|
abduction
|
moves a structure away from the midventral line of the body
|
|
rotation
|
eg foot
|
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pronation
|
palm down
|
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supination
|
palm down
|
|
elasticity
|
connective tissue components of skeletal muscle
|
|
types of architecture for skeletal muscle (4)
|
1. strap
2. fusiform 3. unipennate 4. bipennate *can only contract about third of length |
|
strap and fusiform muscles
|
skeletal muscles
biceps and triceps have longer fibers so longer contractions |
|
pennate muscles
|
more force due to connective tissue elasticity and more myofilaments in a fiber
*chevron shape |
|
muscle fiber types
|
1. twitch (phasic muscles) (slow and fast twitch)
2. tonic muscles |
|
twitch muscles
|
1 muscle fiber - 1 motor end plate. all or none, most muscles
*when get action potentials, immediately contract type 1: slow type 2: fast skeletal muscles |
|
tonic mucles
|
skeletal muscles
-1 muscle fiber-multiple end plates. -More action potentials, more contraction. -Small muscles, -don't fatigue -eye -rare in mammals -only in eye muscles -contract as receive more action potentials, slowly contract more as receive more action potentials |
|
Type I twitch muscles (slow)
|
-rich vascular
- high myoglobin content -oxidative (uses lots of oxygen) -mitochondria -red (bc myoglobin) eg postural muscles, resistant to fatigue eg dark meat of chicken leg, dark band on fish |
|
Type II twitch muscles (fast)
|
-anaerobic by glycolysis
-fewer capillaries -fast-twitch -white in color -fatigue -don't use oxygen energy as much eg bursting movement, biceps, triceps eg white meat on chicken breast, light meat on fish *majority of muscles on fish |
|
muscles are from what part of the embryo?
|
mesoderm
|
|
somitic myotomes turn into
|
somatic muscles
|
|
splanchnic mesoderm turn into
|
visceral muscles
|
|
origin of gut muscle
|
splanchnic muscle
mesoderm |
|
myotome
|
a muscle segment, usually applied to embryonic segments
|
|
where are head muscles from?
|
head paraxial mesoderm
|
|
paraxial mesoderm
|
that portion of the mesoderm that lies just lateral to the neural tube, differentiates into somites in the trunk and caudal part of the head and into somitomeres more rostrally
|
|
extrinsic ocular muscles
|
the group of small muscles that extend from the wall of the orbit to the eyeball and control the movements of the eyeball
|
|
where are skeletal muscle nuclei located?
|
peripherally located nuclei
|
|
characteristics of cardiac muscle (6)
|
1. 1 or 2 nuclei
2. centrally located nucleus 3. striated 4. branched cells 5. intercalated discs 6. huge numbers of mitochondria (.:. need lots of ATP) |
|
where does cardiac muscle come from?
|
in embryo...cardiogenic mesenchyme
|
|
intercalated disks
|
separating adjacent cells in cardiac muscle fibers. Intercalated discs support synchronized contraction of cardiac tissue.
junction b/t 2 cardiac musc |
|
cardiac muscles have no distinct what?
|
myofibrils
|
|
z line connects
|
two sarcomeres together (in cardiac muscle)
|
|
I bands
|
The I bands appear lighter because these regions of the sarcomere mainly contain the thin actin filaments, whose smaller diameter allows the passage of light between them
|
|
T-tubule of cardiac muscle
|
composed of a T-tubule and a single terminal cisterna; it occurs at the Z line.
way to get Ca signal to move to contract sarcomere signal=release of Ca |
|
function of intercalated disks
|
provide electrical coupling
-adheres junctions and desmosomes for actin adhesion, gap junctions for electrical coupling *rapidly spread electrical impulse |
|
gap junction allows
|
rapid signaling of cells (ions pass thru fast)
|
|
heart contraction initiated at...
|
sinoatrial node (SA node) (pacemaker)
|
|
full course of heart contraction
|
-contraction initiated at SA node (pacemaker)
-the at the atrioventricular node (AV node) -then into Purkinje fibers *ensures correct spread of fibers |
|
characteristics of smooth muscle (5)
|
1. no striations
2. single nucleus 3. central nucleus 4. form sheets (huge muscle bands) (eg gut) 5. or single cells (myoepithelial cells) |
|
myoepithelial cells
|
most glands have these (smooth muscles) that contract to help push out excretions
*elongated epithelial cells with contractile properties |
|
smooth muscle contractions
|
very slow..hours or days
responds to nerves, hormones, local concentrations of blood gases actin and myosin used for contraction but not arranged in sarcomeres |
|
how does Ca enter smooth muscles?
|
caveoli in plasma membrane (not t-tubules like cardiac and skeletal)
Ca regulates actin/myosin interaction |
|
smooth muscles linked together by
|
gap junctions to co-ordinate response
activated by autonomic nervous system or hormones |
|
almost all vertebrates have these 6 extrinsic ocular muscles
|
1. dorsal oblique (IV)
2. ventral oblique (III) 3. ventral rectus (III) 4. lateral rectus (VI) 5. dorsal rectus (III) 6. medial rectus (III) |
|
which eye muscles innervated by CN (cranial nerve) III?
|
ventral oblique
ventral rectus medial rectus dorsal rectus *occulomotor |
|
oculomoter nerve
|
the third cranial nerve, which innervates mot of the extrinsic muscles of the eyeball and carries autonomic fibers into the eyeball
|
|
which eye muscles innervated by CN IV?
|
dorsal oblique
*trochlear |
|
trochlear nerve
|
the fourth cranial nerve, which innervates the superior oblique muscle; the mammalian muscle passes through a connective tissue pulley before inserting on the eyeball
|
|
which eye muscles innervated by CN VI?
|
lateral rectus
*abducens |
|
abducens nerve
|
the nerve that innervates the lateral rectus muscle of he eyeball; cranial nerve 6
|
|
some tetrapods also have this occulomotor muscle
|
retractor bulbi
|
|
birds also have these occulomotor muscles
|
levator palperbrae superioris, depressor palpebrae inferioris
|
|
mammals only have..
|
superioris
|
|
muscles from brachiomere 1 (mandibular) (5)
|
1. adductor mandibular
2. levator palatoquadrati 3. spiracularis 4.preorbitalis 5. intermandibularis |
|
muscles from brachiomere 1 innervated by..
|
trigeminal nerve (5th cranial nerve)
|
|
muscles from brachiomere 1 associated with..
|
jaw closing in gnathostomes
|
|
adductor mandibulae function
|
huge, closes jaw (palato to meckel)
from brachiomere 1 |
|
levator palatoquadrati function
|
from brachiomere 1
lifts palatoquadrate during prey capture (otic cap to palato) |
|
spiracularis function
|
from brachiomere 1
controls spiracle (otic cap to palato) |
|
preorbitalis function
|
from brachiomere 1
closes jaw (chondrocran to meckel) |
|
intermandibularis function
|
from brachiomere 1
constricts throat (meckel to mid vent) |
|
what muscles retained for kinetic skulls?
|
levator pterygoidei
protractor pterygoidei |
|
intermandibularis in amphibians becomes what 2 muscles in mammals?
|
mylohyoideus
anterior digastric *intermandibulairs in amph used for air pumping |
|
adductor mandibulae of sharks and amphibians/reptiles becomes what in mammals?
|
temporalis
masseter pterygoideus tensor tympani tensor veli palati |
|
spiracularis and preorbitalis of sharks become what in amphibians and mammals?
|
nothing!
|
|
where do all mandibular muscles insert?
|
lower jaw (dentary bone)
|
|
tensor tympani
|
part of adductor complex remains attached to the ear derivative of quadrate/articular and goes with it
|
|
superficial jaw muscles (of didelphis) (diagram)
|
temporalis, digastric, masseter
|
|
deeper jaw muscles of dedelphis (diagram)
|
pterygoideus
digastric |
|
muscles from brachiomere 2 (3) (hyoid)
|
1. levator hyomandibulae
2. dorsal and ventral hyoid constrictor 3. intermandibularis *all associated with acting on gill puches *mammals dont have (vanished) |
|
muscles from brachiomere 2 innervated by?
|
facial nerve (6th cranial nerve)
|
|
levator hyomandibulae
|
from brachiomere 2 hyoid
compresses gill pouches (otic to hyomandib cartilage) |
|
dorsal and ventral hyoid constrictor
|
from brachiomere 2 hyoid
compresses gill pouches (part of levator hyomandibulae) |
|
intermandibularis
|
from brachiomere 2 hyoid
compresses gill pouches (dorsal to intermandibularis) |
|
new muscle in tetrapods that depresses lower jaw
|
depressor mandibuli
|
|
in mammals, digastric replaces what?
|
mandibulae
|
|
what are the remnants of interhyoideus in mammals?
|
stylohyoid
stapedius |
|
what are the largest remnanats of ventral hyoid muscles in mammals?
|
platysma and facial muscles
*extremely important set of muscles involved in communication, defense, suckling |
|
muscles from brachiomere 3-7 innervated by
|
glossopharyngeal nerve (9th cranial nerve) and vagus nerve (10th cranial nerve)
|
|
muscles from brachiomere 3-7 (4)
|
1. cucularis
2. dorsal and ventral superficial constrictors 3. interacuals, branchial adductor 4. interbranchials |
|
cucularis
|
from brachiomere 3-7
formed by fusion of levators of arches 3-7 (posterior levator to scapular process) elevates scapular process *one muscle spans across shark's back |
|
interarcuals, branchial adductor
|
from brachiomere 3-7
pull gills anteriorly, adducts gill fan shaped, and the muscle between each ray, run between 2 gill rays and connect together |
|
interbranchials
|
from brachiomere 3-7
adducts |
|
cucularis becomes what in mammasl?
|
sternocleidomastoid and trapezius
**used for shoulder and head |
|
interarcuals become what im mammals?
|
muscles of pharynx wall and intrinsic larynx
|
|
hypobranchial muscles consist of..
|
the rest of the muscle before get to axial skeleton
invaders from behind the branchial region muscles located ventral to the gills |
|
in mammals, hypobranchial muscles are associated with...
|
the tongue
|
|
epaxial
|
upper half of each segment
pertaining to structures that lie above or beside the vertebral axis |
|
hypaxial
|
bottom half of each segment
pertaining to structures that lie ventral to the veterbral axis |
|
horizontal septum
|
divides epaxial and hypaxial
gives a double chevron shape (trunk of fish) |
|
myoseptum
|
a connective tissue septum between myomeres
|
|
myomere
|
a muscle segment, usually applied ot adult segments
|
|
overlap of fish trunk muscles ensures...
|
smooth undulations`
|
|
exotendon
|
large group of extracellular muscle
transfers energy to tail and stores energy when stretched trunk musc of fish |
|
slow oxidative muscle fibers
|
the triangle shape of hypaxial muscles on the edge
-doesn't fatigue -fish always undulating -when sitting, feeding, use slow muscle fibers **all other muscles work when fish needs to move fast fish trunk muscles |
|
fast oxidative muscle fibers
|
work when fish need to move fast
fish trunk muscles |
|
segments of salamanders and reptiles trunk
|
body still retains importance in locomotion so trunk remains segmented into myomeres
|
|
what is segmented body used for?
|
locomotion
most is w/ epaxial muscles |
|
2 epaxial muscle groups of tetrapods
|
1. dorsalis trunci
2. interspinalis *hypaxial muscles completely lost their function |
|
dorsalis trunci
|
muscle group of tetrapod epaxial muscles
remain segmented, large and bulky |
|
interspinalis
|
muscle group of tetrapod epaxial muscles
deep, connect adjacent vertebrae, join across group of vertebrae |
|
hypaxial muscles of tetrapods turn into..
|
from a single group to 4 or 5 groups in layers
then from segments to layers *no traces of segmentation |
|
why is segmentation lost in birds and mammals?
|
-locomotion is less important
-need to support the body -need to mediate spine movements -need to move head -need to ventilate lungs |
|
epaxial muscles of birds and mammals (3)
|
1. transversospinalis
2. longissimus dorsi 3. iliocostalis *3 groups of muscles (from outer surface to inner surface) |
|
transversospinalis
|
epaxial muscle group of birds/mammals
shorter between several segments span 2 or 3 vertebrae and bind together |
|
longissimus dorsi
|
epaxial muscle group of birds/mammals
from sacrum (pelvis) to neck |
|
iliocostalis
|
epaxial muscle group of birds/mammals
from sacrum and pelvis to ribs |
|
hypaxial muscle groups of mammals (3)
|
1. subvertebral group
2. ventral 3. lateral group 3 or 4 layers *hypaxial muscles mostly seen in humans |
|
subvertebral group
|
hypaxial muscle group in mammals
deep, quadratus lumborum deep group underneath vertebrae |
|
ventral (hypax muscle grp)
|
hypaxial muscle group in mammals
rectus abdominus connective tissue slits divide into 3 parts (aka the 6 pack) |
|
lateral group 3 or 4 layers
|
hypaxial muscle group in mammals
external oblique internal oblique transversus abdominis + intercostals hold abdominal contents together go in overlapping layers --internal =90 degrees --most internal = trnasverse across body |
|
fins function
|
NOT FOR PROPULSION!
used in lift, stability, braking, maneuvering |
|
where does propulsive power come from? (in fish)
|
tail
|
|
appendicular skeleton of a fin and group of muscles on it and where they are attached
|
dorsal muscle (extensors)
ventral muscles (flexors) attach to pectoral girdle (so fin can move up and down) |
|
limb purpose of tetrapods/mammals
|
-support body
-major propulsive force (for locomotion and support) *early tetrapods had huge muscle mass for supporting) *often major muscle mass of body |
|
dorsal muscles function with limbs
|
extensors, also abductors
|
|
ventral muscles function with limbs
|
flexors, also adductors
*underneath limb buds |
|
why more muscles in mammals?
|
fine movements we do
muscles are much thinner and more precise mammals lost some power in some muscles |
|
the splayed position of reptiles required what?
|
powerful adductors
because of more erect limbs in mammals these ventral adductors are not longer requires |
|
agility of movement...
|
means both dorsal and ventral muscles have multiplied and subdivided
|
|
muscles associated with scapula in tetrapods/mammals are really...
|
are really branchiomeric muscles, evolved from cucullaris
|
|
appendicular muscles are
|
dorsal and ventral groups
|
|
who is jawless and filter feeders?
|
tunicates, cephalochordates, lamprey larvae
|
|
who has an oral cavity?
|
all craniates
*what it does depends on what foods it eats |
|
filter feeding mechanism
|
water drawn in by cilia, expansion of buccal cavity, etc
food particles are trapped in mucus and the mucus moves (it) down to the gut by ciliary action |
|
jawed fish are either...
|
suction feeders(mostly)-create suction in oral cavity and draw and suck in
or ram feeders (overtake prey with mouth open)- swim and grab prey |
|
primative capture
|
combination of suction and ram feeding
eg sharks |
|
for fish to open jaw, these muscles work..
|
-epaxial muscles lift head
-hypaxial, hyoid, and mandibular muscles |
|
lower jaw produces what when opening mouth?
|
enormous gape
|
|
some enlargement of pharynx in fish when opening jaw produces what?
|
suction
|
|
only moving parts of fish mouth
|
first and second arch derivatives (mandibular and hyoid)
|
|
3 muscles that open the lower jaw and provide a little suction in jawed fish
|
1.coracomandibularis
2. rectus cervicis 3. hypaxial muscles |
|
most important part of jaw closing in fish
|
adduction of mandible
*upper jaw loosely attached (only by ligament) so can move |
|
suction feeders (eg bony fish) special features for opening mouth
|
-huge dermal plates are flexible and moveable
-increase in number and motility of bony elements -kinetic skull-all the elements move to rapidly expand the pharynx and generate great suction force |
|
suction feeders (eg bony fish) mechanism for opening mouth
|
-epaxial muscles lift head up
-opercular muscles lifts up operculum -3 sets of muscles open jaw -maxilla moves foreward -premaxilla moves out and forward -mandible moves down |
|
inertial feeding
|
how terrestrial verts eat
capture prey and keep snapping to gradually move it back into throat no water ot suck in, coordinated movements of mandible and tongue replace water flow many primitive terrestrial verts some use tongue and they all swallow food whole or in large pieces - kinetic skulls |
|
pterygoid forward
|
jaw lifts up
|
|
in terrest. vert, movement of jaw opening takes place at
|
transverse joint
|
|
most flexible skulls
|
snakes
|
|
what moves to generate jaw opening?
|
squamosal and quadrate
|
|
cranial kinesis in birds allows
|
a good repertoire of abilities for different foods, shock absorption for woodpeckers
|
|
feeding cycle consists of 4 stages:
|
in all terrestrial verts (including amph, reptiles, birds, mammals)
1. slow opening 2. fast opening 3. fast closing 4.slow closing/power stroke cycle begins w/ slow opening of mandible |
|
slow opening
|
1st stage kinetic skulls: snout lifts up in relation to brain case via transverse hinge
|
|
fast opening
|
2nd stage
sudden and rapid opening of the mouth to maximum gape |
|
fast closing
|
3rd stage
mandible is lifted and the gape decreases rapidly |
|
slow closing/power stroke
|
4th stage
snout is depressed, produces a strong bite |
|
new muscles in mammal mouth opening (non kinetic skulls)
|
digastric (opening)
temporalis (closing) only lower jaw joing moves |
|
new movements in mammal mouth opening (non kinetic skulls)
|
grinding, cutting (depending on herb or carn)
|
|
masseter of mammals
|
move jaw and grind food (instead of cutting)
|
|
some tetrapods that went back to suspension feeding
|
basking sharks
manta rays ducks flamingos baleen whales |
|
muscular tongue
|
very important for moving and swallowing food
tetrapods derived from several areas of floor of pharynx often rough (cats) often used in food gathering(fromgs, salamanders, lizards, anteaters) |
|
rough tongue purpose (eg cats)
|
keratinized region of stratum corneum
keep food in place and move backwards |
|
"outside in" theory
|
similarity to scales of sharks and placoderms had dentine-like scales led to suggestion of teeth from scales
but presence of pharyngeal teeth in teleosts and discovery of pharyngeal teeth in jawless vertebrate fossils suggests "inside out" theory |
|
teeth as fossils
|
excellent as fossils
|
|
development of teeth
|
very similar to hair, etc
evolved from dermal scales from outside-in theory teleosts-no teeth in OC...in pharyngeal |
|
tooth development
|
neural crest cells, remarkably similar to bony scales and even hairs and feathers
develop along ridge of jaw and align where epithelium thicken |
|
odontoblasts cells from
|
neural crest
|
|
ameloblast cells from
|
epithelium
|
|
neural crest cells of teeth
|
teeth from neural crest
teeto from top of neural tube |
|
cap stage
|
tooth development
epithelium swollen in cap |
|
bell stage
|
tooth development
shape of bell |
|
adult teeth kept in place by
|
cement and/or periodontal ligament
sits in jaw b/c of secretion of cement and stays in b/c of periodontal ligament important sensory part of tooth (ligament) |
|
important sensory part of tooth
|
periodontal ligament
(holds tooth in) |
|
polyphyodont
|
most verts
new tooth develops under old one many successive sets of teeth |
|
diphyodont
|
most mammals
2 sets of teeth only |
|
monophyodont
|
toothed whales
1 set of teeth only |
|
sets of teeth..
|
"phyodont"
|
|
tooth attachment
|
"odont"
|
|
acrodont
|
sit on top of jaw
|
|
thecodont
|
sits in deep/pocket
|
|
pleurodont
|
tooth loosely attached to the outside edge of the jaw
|
|
dental formula
|
I 2/2, C 1/1, P 2/2, M 3/3
first #=# teeth above second #= # teeth below human formula |
|
incisors
|
cutting, cropping and picking up
specialized in rodents, endmale on front surface, continually grows, filed down by eating tusks are highly modifed incisors |
|
diastemous
|
gap of missing teeth (eg mouse)
|
|
canines
|
seizing piercing and killing, especially in carnivores
herbivore not use for grabbing so use for defense |
|
premolars/molars
|
combined cutting and crushing, most complex and variable
have 2 or more roots and crown has cusps and crests |
|
first mammals had how many cusps premolars/molars?
|
3 in linear sequence
|
|
symmetrodont
|
early mammal pre/molars that became triabngular and the number of cutting surfaces decreasaed
|
|
tribosphenic
|
teeth of mammals that were triangular with extra cusps
|
|
bunodont
|
teeth of mammals that became square (b/c have 4 cusps)
much better for crushing and grinding action for ombnivores and herbivores no sharp cones, are low hillocks |
|
lophodont
|
cusps have united to form ridges
in specialized herbivores (elephants, rodents, horses, rhinos) form ridges of lophs premolars have become molars |
|
selenodont
|
molars
crescent shaped cusps in specialized herbivores (elephants, rodents, horses, rhinos) cusps formed together |
|
do fish have oral glands?
|
no, except for occasional mucus secreting cells
|
|
do lampreys have oral glands?
|
they have a pair of glands that secrete anti-coagulant
|
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salivary glands
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modified in some snakes to produce neurotoxins and vampire bats to produce anticoagulants
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saliva
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produced by salivary glands
lubricates, moistens, begins digestion (a-amylase), antiseptic (IgA, lysozyme) |
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how does lamprey feed?
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clamp on victim w/ dental scales, rasp bleeds and drink blood
*glands secrete anti-coagulant |
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mandibular gland
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a mammalian salivary gland that is located near the caudal end of hte mandible, or lower jaw
sits under tongue |
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3 glands in mammalian oral cavity
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mandibular gland
sublingual gland parotid gland |
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parotid gland
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a mammalian salivary gland located caudal to the ear
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parotid gland is located by
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out on the masseter muscle
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some mammalian species also have
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zygomatic, buccal, molar glands
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what kind of ducts does salivary glands have?
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exocrine
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what kind of secretion are salivary glands?
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merocrine (put secretion in packet and exocytose)
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2 cell types of salivary glands
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serous cell
mucus cell |
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serous cell
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salivary gland
dark staining, produces a watery, thin secretion |
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mucus cell
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salivary gland
pale staining, proudces a think secretion |
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gut comes from
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endoderm (underlying thin layer)
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endodermal lining
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tube of endoderm that forms gut
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coelom
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a body cavity that is completely lined by an epithelium of mesodermal derivation
forms peritoneal cavity |
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in developing embryo, the yellow hollow tube (dig sys) goes all the way to cloaca, what are the 2 branches and 3 primary regions?
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two branches:
-yolk sac -allantois 3 primary regions -foregut, midgut, hindgut |
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foregut makes..
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most things:
pharynx esophagus duodenum biliary apparatus lungs stomach liver and pancreas (and ducts) |
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gall bladder is a branch of
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the hepatic diverticulum
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pancreas arises from
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2 buds a dorsal and a ventral
ventral swings around to fuse w/ the dorsal made from foregut |
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midgut makes..
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small intestine
appendix 2/3 transverse colon (LI) caecum ascending colon |
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midgut rotates
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almost 360 degrees
twists during devleopment |
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hindgut makes..
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1/3 transverse colon
descending colon sigmoid colon rectum top of anal canal |
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what 2 parts is the hindgut separated into?
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allantois
anal pit group of mesochyme cells push in and split posterior part in two seperate gut from the urogenital system |
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most things we use come from what gut?
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front and mid gut
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ground plan of gut, from outer to inner
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outermost:
epidermis lamina propria muscuaris mucosa connective tissue circular smooth muscle longitudinal smooth muscle connective tissue serosa |
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lumen of gut
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middle of gut
epithelial layer of single epidermal cells (one row) |
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lamina propria
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epidermal cells sit on this connective tissue
contains lymphoid aggregations |
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mucosa layer of gut contains
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3 layers:
epidermis lamina propria muscuaris mucosa |
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lymphoid aggregation
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in lamina propria (mucosa layer of gut)
lymph nodes just elow the epidermis, protects from bacterial infection from stuffwe might eat |
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muscularis mucosa
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in mucosa layer
below lamina propria |
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submucosa composed of..
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connective tissue
located under mucosa layer (under muscuaris mucosa) |
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muscularis externa composed of
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circular smooth muscle
lontitudinal smooth muscle outside muscles |
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lontitidunal smooth muscles operated by
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sympathetic nervous system
part of muscularis externa |
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enteric plecus
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located in longitudinal smooth muscle of muscularis externa
lots of nervous tissue |
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serosa
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thin epithelium
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esophagus function
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conduction
conduct food from pharynx to stomach, quite muscular |
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crop
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in grain and seed eating birds
part of eso swells into crop sac that serves to store and soften, produces milky secretions for young |
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hoatzin
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has a fermentation chamber to break down cellulose
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eso of egg eating snakes
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eso crushes the egg
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stratified squamous epithelium
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esophagus
cornified for protection epithelium of esophagus need to protect from hard food has many layers |
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skeletal muscle in eso
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skeletal uscle at top, mixed in the middle, smooth muscle at bottom
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submucosal glands
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for lubrication
deep in mucosa |
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variation of esophagus
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is in epithelium
smooth muscle is everywhere else top of eso starts w/ skeletal muscle b/c control action of swallowing |
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stomach function
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mechanical and chemical breakdown
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who does not have a stomach?
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tunicates, amphioxux, hagfish, lamprey
*filter feeders |
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intermittent feeding and stomach
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may have been primitive craniate condition and stomach evolved when feeding became intermittent (ex snakes)
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HCl in stomach could have been for?
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HCl production could have been for killing bacteria and preserving food for storage
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stomach secondarily lost in
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when food is very small particles as in lungfish, carp-like fish
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different regions of stomach
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fundus, body, pyloric sphincter
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fundus
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top part of stomach
usually filled w/ air |
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pyloric sphincter
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botth part of stomach
keeps food in until it has been mechanically and chemically broken down |
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stomach has 3 layers of muscularis externa
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smooth muscle w/ ridge structure - rugae
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gastric pits
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chemical part comes from indentations of epithelium
secretory make 3 cells: mucus cells (mucus) parietal cells (0,1 M HCl) peptic cells (pepsin) |
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what pH does pepsin work at?
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pH 4
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chitinase
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produced by amph, reptiles, birds
digests chitin (exoskeleton of bugs) made in stomach |
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renin
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curdles milk so protein can be more slowly digested
produced by young mammals (suckling milk) |
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gizzard
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from posterior stomach in some fish, some reptiles and all birds
proventriculus from anterior stomach in birds contains stones for grinding, birds have no teeth |
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bird stomach divided into
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proventriculus and gizzard
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herbivores stomach/colon
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plant food is abundant, but very poor in energy and protein content, need large volumes and slow passage to digest it
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ruminants
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have large, 4 chambered stomaches
hippos, giraffes, camels |
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4 regions of rumen stomach
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rumen
reticulum omasum abomasum *only abomasum has glands (gastric pits?), rest have stratified squamous like eso |
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when rumen eats..
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sits in stomach (~80 hrs) ferments via bacterial and protozoa
by produces are CO2 and methane |
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how does rumen ferment
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bacteria and protozoa produce cellulase, ferments cellulose to organic acids CO2 and methane
147 kg methane/year |
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small intestine function
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mostly digestion and absorption
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from duodenum
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bile from liver emulsifies fats
enzymes from pancreas enzymatically digest food pH increased to 7 by glands and bile *panc enz squirted into duo to start breaking down |
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microvilli increase surface area
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villi increase surface area, microvilli increase surface area from 0.5 to 250 sq m = EQUAL TO TENNIS COURT
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enterocytes
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for absorption
dispersed b/t goblet cells |
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goblet cells
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contain mucus
in lamina propria |
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crypts
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stem cells
in small intes rapid cell division of stem cells migration of cells up from the villus from the crypts *chemotherapy - stop division of stem cells and sloughed off |
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what determines length and surface of intestine?
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degree of activity and metabolism
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spiral valve function
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in intestine
increase area and transit time to absorb more |
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intestine starts to coil in
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bony fishes
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pyloric caeca
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most teleosts have
sometims with special enzymes (ex was lipase) like hairs in outside of stomach |
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first appearance of breakdown of seperate sections in intestines
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frog and land tetrapods
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endotherm intestines
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lonter intestine, more folding (lots of vili), greater energy requirements (up to 25x body length in herb mammals but 3.5x in omnivores and carnivores)
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colon of mammals function
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water recovery and storage of feces
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when food enters LI
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should already have absorbed food
not lots of villi/microvilli absorption of wahter storage of feces to prevent bac infection |
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herbivores w/o a chambered stomach
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horse, rodents,rabbits, etc
have hindgut fermentation where the bacteria lodge *cows are foregut fermenters |
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hindgut fermentation
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less efficient than foregut fermentation (rumination and transit time 80 hrs)
only get to masticate it once (horse feces and cow dung) and transit time 48 hrs |
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foregut fermenters
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have overall advantage and can survive in low quality areas
eg mountain sheep and goats and camels better digestion than hindgut |
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coprophagy
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eat their feces
smaller hindgus fermenters undergo eat 20-60% of feces |
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liver size
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largest organ in body in all vertebrates
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lobules
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"paving stones" of liver
*ONE MILLION HEPATIC LOBULES IN LIVER |
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hepatic lobules structure
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have hepatic vein and 6 portal triads @ end
blood comes in with portal triad |
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triad (4 components)
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-hepatic portal vein (take food away from liver ot body)
-hepatic artery (bring oxygen blood to keep cell alive) -bile duct (store bile) lymphatic |
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internal structure of hepatic lobule
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hepatocytes in rows with sinusoids (where blood drains past) in between
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blood cell's view of a sinusoid
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gaps between the cells lining the capillary
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bile made in..
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hepatocytes
leave down bile canaliculi which are small channels between hepatocytes |
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liver functions(6)
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1. exocrine (secretes bile)
2. stores carbs lipids, proteins, vitamins 3. synthesises plasma proteins, lipoproteins 4. metabolizes and detoxifies (drugs, etc) 5. destroys red blood cells and reclaims products 6. site of haematopoiesis in embryo (where blood made) |
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who has pancreas?
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all craniates, but lampreys, teleoosts it is scattered in intestinal wall and mesentary
still do all same functions |
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2 parts to pancreas
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*exocrine (digestion)
*endocrine (islets of langerhans) |
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exocrine part of pancreas
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makes 15 enzymes for digestion
all secreted in proenzyme form and activated in duodenum typical branched acinar structure merocrine secretion |
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centroacinar cell
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part of pancreas
secrete bicarb ions to buffer pH to 7 |
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structure of acinus and duct
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centroacinar cell
zymogen granules intercalated duct excretory duct |
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islets of langerhans
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endocrine
profuse blood supply ball of cells producing insulin, glucagon, somatostatin, VIP and PP *rich blood supply *makes product and put straight into blood |
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products produced by islets of langerhans
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insulin
glucagon pancreatic polypeptides (PP) somatostatin |