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313 Cards in this Set

  • Front
  • Back
myofibre
myotube in development
myocyte
myoblast in development

cell in muscle
location of actin and myosin?
cytoplasm
3 types of muscle
skeletal, cardiac, smooth

*tendons are continuous with the outer coating
epimysium
the whole skeletal muscle is wrapped in this

(outside layer?)
fascicle
a small bundle of muscle or nerve fibers

bound together by connective tissue

outermost layer of skeletal muscle
perimysium
connective tissue that groups fibers into a fascicle

'middle layer of skeletal muscle'
endomysium
inner most layer of skeletal muscle

binds muscle fibers together to form a fascicle
characteristics of skeletal muscle fibers (4)
1. large (.1-.5 mm diameter, 1cm++length)
2) multinucleate (100s of nuclei)
3) peripheraly located nuclei
4) striated

**cells fuse together and make one multinucleated cell
syncytium
multiple cells coming together and maintaining nuclei

-skeletal muscle
where is the sarcomeric organization of muscle fibers in a cell?
cytoplasm

-cytoplasm has parallel striations from top to bottom
A band
anisotropic
I band
isotropic
M line
thin line down the muscle

-extra proteins down middle of M line
sarcomere
basic contractile unit of piece of muscle
Z line
form left and right hand edge of one sarcomere
where is the thin actin filament attached to?
Z line
sliding filament hypothesis
sucker walk along actin and the myosin moves

ATP hydrolysis causes flexing of cross-bridges
motor end plate
end plate where all the synapses are

motor bc muscle motor neurons
how many muscle fibers can one motor neuron innervate?
a few to thousands
what is the stimulus for a skeletal muscle to contract?
motor neuron
T-tubule
channel system in skeletal muscle

signal down from outside and traverses to cysteinine?
triad
skeletal muscle

T-tubule channel system

is at every sarcomere, and is the recipient
action potentials in sarcomeres
action potential from the end plate gets to every sarcomere in T-tubule syste, Ca releases, acts on actin to allow cross-bridges

vessicles are the receptors telling you to fire action potential
ATP for contractions from??
mitochondria
damaged skeletal muscle
bust open cell and all myofibrils bust out

cell can never recover
satellite cells
for regeneration and repair

"stem cells of muscles"

divide and replace dead myofibers
organization of muscles (skeletal)
epimysium-tendon-perimysium (inner)

usually arranged in antagonistic groups of flexors and extensors
muscle origin
origin is proximal

origin doesn't move

top of muscle; where attaches
muscle insertion
insertion is distal

insertion usually moves

bottom of muscle
isotonic
shortening of muscle against constant load

mode of contraction
isometric
mode of contraction

tension develops but little movement

constant load but no movement
flexion
movement that brings a distal limb segment toward the next proximal segment, advances a limb at the shoulder or hip, or bends the head or a part of the trunk toward the midventral line

opposite of extension

eg elbow, hand
extension
movement that carries a distal limb segment away from the next proximal segment, retracts a limb at the shoulder or hip, or moves the head or a part of the trunk toward the mid-dorsal line

opposite of flexion

eg, elbow, hand
protraction
muscle contraction that moves the entire appendage of a quadruped forward

opposite of retraction

eg shoulder, thigh (take a step)
retraction
action that moves the entire appendage of a quadruped backward

opposite of protraction
eg shoulder, thigh
adduction
moves a structure toward the midventral line of the body

eg leg

ADD
abduction
moves a structure away from the midventral line of the body
rotation
eg foot
pronation
palm down
supination
palm down
elasticity
connective tissue components of skeletal muscle
types of architecture for skeletal muscle (4)
1. strap
2. fusiform
3. unipennate
4. bipennate

*can only contract about third of length
strap and fusiform muscles
skeletal muscles

biceps and triceps

have longer fibers so longer contractions
pennate muscles
more force due to connective tissue elasticity and more myofilaments in a fiber

*chevron shape
muscle fiber types
1. twitch (phasic muscles) (slow and fast twitch)
2. tonic muscles
twitch muscles
1 muscle fiber - 1 motor end plate. all or none, most muscles

*when get action potentials, immediately contract

type 1: slow
type 2: fast

skeletal muscles
tonic mucles
skeletal muscles

-1 muscle fiber-multiple end plates.
-More action potentials, more contraction.
-Small muscles,
-don't fatigue
-eye

-rare in mammals
-only in eye muscles
-contract as receive more action potentials, slowly contract more as receive more action potentials
Type I twitch muscles (slow)
-rich vascular
- high myoglobin content
-oxidative (uses lots of oxygen)
-mitochondria
-red (bc myoglobin)

eg postural muscles, resistant to fatigue

eg dark meat of chicken leg, dark band on fish
Type II twitch muscles (fast)
-anaerobic by glycolysis
-fewer capillaries
-fast-twitch
-white in color
-fatigue
-don't use oxygen energy as much

eg bursting movement, biceps, triceps

eg white meat on chicken breast, light meat on fish

*majority of muscles on fish
muscles are from what part of the embryo?
mesoderm
somitic myotomes turn into
somatic muscles
splanchnic mesoderm turn into
visceral muscles
origin of gut muscle
splanchnic muscle

mesoderm
myotome
a muscle segment, usually applied to embryonic segments
where are head muscles from?
head paraxial mesoderm
paraxial mesoderm
that portion of the mesoderm that lies just lateral to the neural tube, differentiates into somites in the trunk and caudal part of the head and into somitomeres more rostrally
extrinsic ocular muscles
the group of small muscles that extend from the wall of the orbit to the eyeball and control the movements of the eyeball
where are skeletal muscle nuclei located?
peripherally located nuclei
characteristics of cardiac muscle (6)
1. 1 or 2 nuclei
2. centrally located nucleus
3. striated
4. branched cells
5. intercalated discs
6. huge numbers of mitochondria (.:. need lots of ATP)
where does cardiac muscle come from?
in embryo...cardiogenic mesenchyme
intercalated disks
separating adjacent cells in cardiac muscle fibers. Intercalated discs support synchronized contraction of cardiac tissue.

junction b/t 2 cardiac musc
cardiac muscles have no distinct what?
myofibrils
z line connects
two sarcomeres together (in cardiac muscle)
I bands
The I bands appear lighter because these regions of the sarcomere mainly contain the thin actin filaments, whose smaller diameter allows the passage of light between them
T-tubule of cardiac muscle
composed of a T-tubule and a single terminal cisterna; it occurs at the Z line.

way to get Ca signal to move to contract sarcomere

signal=release of Ca
function of intercalated disks
provide electrical coupling
-adheres junctions and desmosomes for actin adhesion, gap junctions for electrical coupling

*rapidly spread electrical impulse
gap junction allows
rapid signaling of cells (ions pass thru fast)
heart contraction initiated at...
sinoatrial node (SA node) (pacemaker)
full course of heart contraction
-contraction initiated at SA node (pacemaker)
-the at the atrioventricular node (AV node)
-then into Purkinje fibers

*ensures correct spread of fibers
characteristics of smooth muscle (5)
1. no striations
2. single nucleus
3. central nucleus
4. form sheets (huge muscle bands) (eg gut)
5. or single cells (myoepithelial cells)
myoepithelial cells
most glands have these (smooth muscles) that contract to help push out excretions

*elongated epithelial cells with contractile properties
smooth muscle contractions
very slow..hours or days

responds to nerves, hormones, local concentrations of blood gases

actin and myosin used for contraction but not arranged in sarcomeres
how does Ca enter smooth muscles?
caveoli in plasma membrane (not t-tubules like cardiac and skeletal)

Ca regulates actin/myosin interaction
smooth muscles linked together by
gap junctions to co-ordinate response

activated by autonomic nervous system or hormones
almost all vertebrates have these 6 extrinsic ocular muscles
1. dorsal oblique (IV)
2. ventral oblique (III)
3. ventral rectus (III)
4. lateral rectus (VI)
5. dorsal rectus (III)
6. medial rectus (III)
which eye muscles innervated by CN (cranial nerve) III?
ventral oblique
ventral rectus
medial rectus
dorsal rectus

*occulomotor
oculomoter nerve
the third cranial nerve, which innervates mot of the extrinsic muscles of the eyeball and carries autonomic fibers into the eyeball
which eye muscles innervated by CN IV?
dorsal oblique

*trochlear
trochlear nerve
the fourth cranial nerve, which innervates the superior oblique muscle; the mammalian muscle passes through a connective tissue pulley before inserting on the eyeball
which eye muscles innervated by CN VI?
lateral rectus

*abducens
abducens nerve
the nerve that innervates the lateral rectus muscle of he eyeball; cranial nerve 6
some tetrapods also have this occulomotor muscle
retractor bulbi
birds also have these occulomotor muscles
levator palperbrae superioris, depressor palpebrae inferioris
mammals only have..
superioris
muscles from brachiomere 1 (mandibular) (5)
1. adductor mandibular
2. levator palatoquadrati
3. spiracularis
4.preorbitalis
5. intermandibularis
muscles from brachiomere 1 innervated by..
trigeminal nerve (5th cranial nerve)
muscles from brachiomere 1 associated with..
jaw closing in gnathostomes
adductor mandibulae function
huge, closes jaw (palato to meckel)

from brachiomere 1
levator palatoquadrati function
from brachiomere 1

lifts palatoquadrate during prey capture (otic cap to palato)
spiracularis function
from brachiomere 1

controls spiracle (otic cap to palato)
preorbitalis function
from brachiomere 1

closes jaw (chondrocran to meckel)
intermandibularis function
from brachiomere 1

constricts throat (meckel to mid vent)
what muscles retained for kinetic skulls?
levator pterygoidei
protractor pterygoidei
intermandibularis in amphibians becomes what 2 muscles in mammals?
mylohyoideus
anterior digastric


*intermandibulairs in amph used for air pumping
adductor mandibulae of sharks and amphibians/reptiles becomes what in mammals?
temporalis
masseter
pterygoideus
tensor tympani
tensor veli palati
spiracularis and preorbitalis of sharks become what in amphibians and mammals?
nothing!
where do all mandibular muscles insert?
lower jaw (dentary bone)
tensor tympani
part of adductor complex remains attached to the ear derivative of quadrate/articular and goes with it
superficial jaw muscles (of didelphis) (diagram)
temporalis, digastric, masseter
deeper jaw muscles of dedelphis (diagram)
pterygoideus
digastric
muscles from brachiomere 2 (3) (hyoid)
1. levator hyomandibulae
2. dorsal and ventral hyoid constrictor
3. intermandibularis

*all associated with acting on gill puches
*mammals dont have (vanished)
muscles from brachiomere 2 innervated by?
facial nerve (6th cranial nerve)
levator hyomandibulae
from brachiomere 2 hyoid

compresses gill pouches (otic to hyomandib cartilage)
dorsal and ventral hyoid constrictor
from brachiomere 2 hyoid

compresses gill pouches (part of levator hyomandibulae)
intermandibularis
from brachiomere 2 hyoid

compresses gill pouches (dorsal to intermandibularis)
new muscle in tetrapods that depresses lower jaw
depressor mandibuli
in mammals, digastric replaces what?
mandibulae
what are the remnants of interhyoideus in mammals?
stylohyoid
stapedius
what are the largest remnanats of ventral hyoid muscles in mammals?
platysma and facial muscles

*extremely important set of muscles involved in communication, defense, suckling
muscles from brachiomere 3-7 innervated by
glossopharyngeal nerve (9th cranial nerve) and vagus nerve (10th cranial nerve)
muscles from brachiomere 3-7 (4)
1. cucularis
2. dorsal and ventral superficial constrictors
3. interacuals, branchial adductor
4. interbranchials
cucularis
from brachiomere 3-7

formed by fusion of levators of arches 3-7 (posterior levator to scapular process)

elevates scapular process

*one muscle spans across shark's back
interarcuals, branchial adductor
from brachiomere 3-7

pull gills anteriorly, adducts gill

fan shaped, and the muscle between each ray, run between 2 gill rays and connect together
interbranchials
from brachiomere 3-7

adducts
cucularis becomes what in mammasl?
sternocleidomastoid and trapezius

**used for shoulder and head
interarcuals become what im mammals?
muscles of pharynx wall and intrinsic larynx
hypobranchial muscles consist of..
the rest of the muscle before get to axial skeleton

invaders from behind the branchial region

muscles located ventral to the gills
in mammals, hypobranchial muscles are associated with...
the tongue
epaxial
upper half of each segment

pertaining to structures that lie above or beside the vertebral axis
hypaxial
bottom half of each segment

pertaining to structures that lie ventral to the veterbral axis
horizontal septum
divides epaxial and hypaxial

gives a double chevron shape (trunk of fish)
myoseptum
a connective tissue septum between myomeres
myomere
a muscle segment, usually applied ot adult segments
overlap of fish trunk muscles ensures...
smooth undulations`
exotendon
large group of extracellular muscle

transfers energy to tail and stores energy when stretched

trunk musc of fish
slow oxidative muscle fibers
the triangle shape of hypaxial muscles on the edge

-doesn't fatigue
-fish always undulating
-when sitting, feeding, use slow muscle fibers

**all other muscles work when fish needs to move fast

fish trunk muscles
fast oxidative muscle fibers
work when fish need to move fast

fish trunk muscles
segments of salamanders and reptiles trunk
body still retains importance in locomotion so trunk remains segmented into myomeres
what is segmented body used for?
locomotion

most is w/ epaxial muscles
2 epaxial muscle groups of tetrapods
1. dorsalis trunci
2. interspinalis

*hypaxial muscles completely lost their function
dorsalis trunci
muscle group of tetrapod epaxial muscles

remain segmented, large and bulky
interspinalis
muscle group of tetrapod epaxial muscles

deep, connect adjacent vertebrae, join across group of vertebrae
hypaxial muscles of tetrapods turn into..
from a single group to 4 or 5 groups in layers

then from segments to layers

*no traces of segmentation
why is segmentation lost in birds and mammals?
-locomotion is less important
-need to support the body
-need to mediate spine movements
-need to move head
-need to ventilate lungs
epaxial muscles of birds and mammals (3)
1. transversospinalis
2. longissimus dorsi
3. iliocostalis

*3 groups of muscles (from outer surface to inner surface)
transversospinalis
epaxial muscle group of birds/mammals

shorter between several segments

span 2 or 3 vertebrae and bind together
longissimus dorsi
epaxial muscle group of birds/mammals

from sacrum (pelvis) to neck
iliocostalis
epaxial muscle group of birds/mammals

from sacrum and pelvis to ribs
hypaxial muscle groups of mammals (3)
1. subvertebral group
2. ventral
3. lateral group 3 or 4 layers

*hypaxial muscles mostly seen in humans
subvertebral group
hypaxial muscle group in mammals

deep, quadratus lumborum

deep group underneath vertebrae
ventral (hypax muscle grp)
hypaxial muscle group in mammals

rectus abdominus

connective tissue slits divide into 3 parts (aka the 6 pack)
lateral group 3 or 4 layers
hypaxial muscle group in mammals

external oblique
internal oblique
transversus abdominis + intercostals

hold abdominal contents together

go in overlapping layers
--internal =90 degrees
--most internal = trnasverse across body
fins function
NOT FOR PROPULSION!

used in lift, stability, braking, maneuvering
where does propulsive power come from? (in fish)
tail
appendicular skeleton of a fin and group of muscles on it and where they are attached
dorsal muscle (extensors)
ventral muscles (flexors)

attach to pectoral girdle (so fin can move up and down)
limb purpose of tetrapods/mammals
-support body
-major propulsive force
(for locomotion and support)

*early tetrapods had huge muscle mass for supporting)

*often major muscle mass of body
dorsal muscles function with limbs
extensors, also abductors
ventral muscles function with limbs
flexors, also adductors

*underneath limb buds
why more muscles in mammals?
fine movements we do

muscles are much thinner and more precise

mammals lost some power in some muscles
the splayed position of reptiles required what?
powerful adductors

because of more erect limbs in mammals these ventral adductors are not longer requires
agility of movement...
means both dorsal and ventral muscles have multiplied and subdivided
muscles associated with scapula in tetrapods/mammals are really...
are really branchiomeric muscles, evolved from cucullaris
appendicular muscles are
dorsal and ventral groups
who is jawless and filter feeders?
tunicates, cephalochordates, lamprey larvae
who has an oral cavity?
all craniates

*what it does depends on what foods it eats
filter feeding mechanism
water drawn in by cilia, expansion of buccal cavity, etc

food particles are trapped in mucus and the mucus moves (it) down to the gut by ciliary action
jawed fish are either...
suction feeders(mostly)-create suction in oral cavity and draw and suck in

or

ram feeders (overtake prey with mouth open)- swim and grab prey
primative capture
combination of suction and ram feeding

eg sharks
for fish to open jaw, these muscles work..
-epaxial muscles lift head
-hypaxial, hyoid, and mandibular muscles
lower jaw produces what when opening mouth?
enormous gape
some enlargement of pharynx in fish when opening jaw produces what?
suction
only moving parts of fish mouth
first and second arch derivatives (mandibular and hyoid)
3 muscles that open the lower jaw and provide a little suction in jawed fish
1.coracomandibularis
2. rectus cervicis
3. hypaxial muscles
most important part of jaw closing in fish
adduction of mandible

*upper jaw loosely attached (only by ligament) so can move
suction feeders (eg bony fish) special features for opening mouth
-huge dermal plates are flexible and moveable

-increase in number and motility of bony elements

-kinetic skull-all the elements move to rapidly expand the pharynx and generate great suction force
suction feeders (eg bony fish) mechanism for opening mouth
-epaxial muscles lift head up
-opercular muscles lifts up operculum
-3 sets of muscles open jaw
-maxilla moves foreward
-premaxilla moves out and forward
-mandible moves down
inertial feeding
how terrestrial verts eat

capture prey and keep snapping to gradually move it back into throat

no water ot suck in, coordinated movements of mandible and tongue replace water flow

many primitive terrestrial verts

some use tongue and they all swallow food whole or in large pieces - kinetic skulls
pterygoid forward
jaw lifts up
in terrest. vert, movement of jaw opening takes place at
transverse joint
most flexible skulls
snakes
what moves to generate jaw opening?
squamosal and quadrate
cranial kinesis in birds allows
a good repertoire of abilities for different foods, shock absorption for woodpeckers
feeding cycle consists of 4 stages:
in all terrestrial verts (including amph, reptiles, birds, mammals)

1. slow opening
2. fast opening
3. fast closing
4.slow closing/power stroke

cycle begins w/ slow opening of mandible
slow opening
1st stage kinetic skulls: snout lifts up in relation to brain case via transverse hinge
fast opening
2nd stage

sudden and rapid opening of the mouth to maximum gape
fast closing
3rd stage

mandible is lifted and the gape decreases rapidly
slow closing/power stroke
4th stage

snout is depressed, produces a strong bite
new muscles in mammal mouth opening (non kinetic skulls)
digastric (opening)
temporalis (closing)

only lower jaw joing moves
new movements in mammal mouth opening (non kinetic skulls)
grinding, cutting (depending on herb or carn)
masseter of mammals
move jaw and grind food (instead of cutting)
some tetrapods that went back to suspension feeding
basking sharks
manta rays
ducks
flamingos
baleen whales
muscular tongue
very important for moving and swallowing food

tetrapods

derived from several areas of floor of pharynx

often rough (cats)

often used in food gathering(fromgs, salamanders, lizards, anteaters)
rough tongue purpose (eg cats)
keratinized region of stratum corneum

keep food in place and move backwards
"outside in" theory
similarity to scales of sharks and placoderms had dentine-like scales led to suggestion of teeth from scales

but presence of pharyngeal teeth in teleosts and discovery of pharyngeal teeth in jawless vertebrate fossils suggests "inside out" theory
teeth as fossils
excellent as fossils
development of teeth
very similar to hair, etc

evolved from dermal scales from outside-in theory

teleosts-no teeth in OC...in pharyngeal
tooth development
neural crest cells, remarkably similar to bony scales and even hairs and feathers

develop along ridge of jaw and align where epithelium thicken
odontoblasts cells from
neural crest
ameloblast cells from
epithelium
neural crest cells of teeth
teeth from neural crest

teeto from top of neural tube
cap stage
tooth development

epithelium swollen in cap
bell stage
tooth development

shape of bell
adult teeth kept in place by
cement and/or periodontal ligament

sits in jaw b/c of secretion of cement and stays in b/c of periodontal ligament

important sensory part of tooth (ligament)
important sensory part of tooth
periodontal ligament

(holds tooth in)
polyphyodont
most verts

new tooth develops under old one

many successive sets of teeth
diphyodont
most mammals

2 sets of teeth only
monophyodont
toothed whales

1 set of teeth only
sets of teeth..
"phyodont"
tooth attachment
"odont"
acrodont
sit on top of jaw
thecodont
sits in deep/pocket
pleurodont
tooth loosely attached to the outside edge of the jaw
dental formula
I 2/2, C 1/1, P 2/2, M 3/3

first #=# teeth above
second #= # teeth below

human formula
incisors
cutting, cropping and picking up

specialized in rodents, endmale on front surface, continually grows, filed down by eating

tusks are highly modifed incisors
diastemous
gap of missing teeth (eg mouse)
canines
seizing piercing and killing, especially in carnivores

herbivore not use for grabbing so use for defense
premolars/molars
combined cutting and crushing, most complex and variable

have 2 or more roots and crown has cusps and crests
first mammals had how many cusps premolars/molars?
3 in linear sequence
symmetrodont
early mammal pre/molars that became triabngular and the number of cutting surfaces decreasaed
tribosphenic
teeth of mammals that were triangular with extra cusps
bunodont
teeth of mammals that became square (b/c have 4 cusps)

much better for crushing and grinding action for ombnivores and herbivores

no sharp cones, are low hillocks
lophodont
cusps have united to form ridges

in specialized herbivores (elephants, rodents, horses, rhinos)

form ridges of lophs

premolars have become molars
selenodont
molars

crescent shaped cusps

in specialized herbivores (elephants, rodents, horses, rhinos)

cusps formed together
do fish have oral glands?
no, except for occasional mucus secreting cells
do lampreys have oral glands?
they have a pair of glands that secrete anti-coagulant
salivary glands
modified in some snakes to produce neurotoxins and vampire bats to produce anticoagulants
saliva
produced by salivary glands

lubricates, moistens, begins digestion (a-amylase), antiseptic (IgA, lysozyme)
how does lamprey feed?
clamp on victim w/ dental scales, rasp bleeds and drink blood

*glands secrete anti-coagulant
mandibular gland
a mammalian salivary gland that is located near the caudal end of hte mandible, or lower jaw

sits under tongue
3 glands in mammalian oral cavity
mandibular gland
sublingual gland
parotid gland
parotid gland
a mammalian salivary gland located caudal to the ear
parotid gland is located by
out on the masseter muscle
some mammalian species also have
zygomatic, buccal, molar glands
what kind of ducts does salivary glands have?
exocrine
what kind of secretion are salivary glands?
merocrine (put secretion in packet and exocytose)
2 cell types of salivary glands
serous cell

mucus cell
serous cell
salivary gland

dark staining, produces a watery, thin secretion
mucus cell
salivary gland

pale staining, proudces a think secretion
gut comes from
endoderm (underlying thin layer)
endodermal lining
tube of endoderm that forms gut
coelom
a body cavity that is completely lined by an epithelium of mesodermal derivation

forms peritoneal cavity
in developing embryo, the yellow hollow tube (dig sys) goes all the way to cloaca, what are the 2 branches and 3 primary regions?
two branches:
-yolk sac
-allantois

3 primary regions
-foregut, midgut, hindgut
foregut makes..
most things:

pharynx
esophagus
duodenum
biliary apparatus
lungs
stomach
liver and pancreas (and ducts)
gall bladder is a branch of
the hepatic diverticulum
pancreas arises from
2 buds a dorsal and a ventral

ventral swings around to fuse w/ the dorsal

made from foregut
midgut makes..
small intestine
appendix
2/3 transverse colon (LI)
caecum
ascending colon
midgut rotates
almost 360 degrees

twists during devleopment
hindgut makes..
1/3 transverse colon
descending colon
sigmoid colon
rectum
top of anal canal
what 2 parts is the hindgut separated into?
allantois
anal pit

group of mesochyme cells push in and split posterior part in two seperate gut from the urogenital system
most things we use come from what gut?
front and mid gut
ground plan of gut, from outer to inner
outermost:
epidermis
lamina propria
muscuaris mucosa
connective tissue
circular smooth muscle
longitudinal smooth muscle
connective tissue
serosa
lumen of gut
middle of gut
epithelial layer of single epidermal cells (one row)
lamina propria
epidermal cells sit on this connective tissue

contains lymphoid aggregations
mucosa layer of gut contains
3 layers:
epidermis
lamina propria
muscuaris mucosa
lymphoid aggregation
in lamina propria (mucosa layer of gut)

lymph nodes

just elow the epidermis, protects from bacterial infection from stuffwe might eat
muscularis mucosa
in mucosa layer

below lamina propria
submucosa composed of..
connective tissue

located under mucosa layer (under muscuaris mucosa)
muscularis externa composed of
circular smooth muscle
lontitudinal smooth muscle

outside muscles
lontitidunal smooth muscles operated by
sympathetic nervous system

part of muscularis externa
enteric plecus
located in longitudinal smooth muscle of muscularis externa

lots of nervous tissue
serosa
thin epithelium
esophagus function
conduction

conduct food from pharynx to stomach, quite muscular
crop
in grain and seed eating birds

part of eso swells into crop

sac that serves to store and soften, produces milky secretions for young
hoatzin
has a fermentation chamber to break down cellulose
eso of egg eating snakes
eso crushes the egg
stratified squamous epithelium
esophagus
cornified for protection

epithelium of esophagus need to protect from hard food

has many layers
skeletal muscle in eso
skeletal uscle at top, mixed in the middle, smooth muscle at bottom
submucosal glands
for lubrication

deep in mucosa
variation of esophagus
is in epithelium

smooth muscle is everywhere else

top of eso starts w/ skeletal muscle b/c control action of swallowing
stomach function
mechanical and chemical breakdown
who does not have a stomach?
tunicates, amphioxux, hagfish, lamprey

*filter feeders
intermittent feeding and stomach
may have been primitive craniate condition and stomach evolved when feeding became intermittent (ex snakes)
HCl in stomach could have been for?
HCl production could have been for killing bacteria and preserving food for storage
stomach secondarily lost in
when food is very small particles as in lungfish, carp-like fish
different regions of stomach
fundus, body, pyloric sphincter
fundus
top part of stomach

usually filled w/ air
pyloric sphincter
botth part of stomach

keeps food in until it has been mechanically and chemically broken down
stomach has 3 layers of muscularis externa
smooth muscle w/ ridge structure - rugae
gastric pits
chemical part comes from indentations of epithelium

secretory

make 3 cells:
mucus cells (mucus)
parietal cells (0,1 M HCl)
peptic cells (pepsin)
what pH does pepsin work at?
pH 4
chitinase
produced by amph, reptiles, birds

digests chitin (exoskeleton of bugs)

made in stomach
renin
curdles milk so protein can be more slowly digested

produced by young mammals (suckling milk)
gizzard
from posterior stomach in some fish, some reptiles and all birds

proventriculus from anterior stomach in birds

contains stones for grinding, birds have no teeth
bird stomach divided into
proventriculus and gizzard
herbivores stomach/colon
plant food is abundant, but very poor in energy and protein content, need large volumes and slow passage to digest it
ruminants
have large, 4 chambered stomaches

hippos, giraffes, camels
4 regions of rumen stomach
rumen
reticulum
omasum
abomasum

*only abomasum has glands (gastric pits?), rest have stratified squamous like eso
when rumen eats..
sits in stomach (~80 hrs) ferments via bacterial and protozoa

by produces are CO2 and methane
how does rumen ferment
bacteria and protozoa produce cellulase, ferments cellulose to organic acids CO2 and methane

147 kg methane/year
small intestine function
mostly digestion and absorption
from duodenum
bile from liver emulsifies fats
enzymes from pancreas enzymatically digest food
pH increased to 7 by glands and bile

*panc enz squirted into duo to start breaking down
microvilli increase surface area
villi increase surface area, microvilli increase surface area from 0.5 to 250 sq m = EQUAL TO TENNIS COURT
enterocytes
for absorption

dispersed b/t goblet cells
goblet cells
contain mucus

in lamina propria
crypts
stem cells

in small intes

rapid cell division of stem cells

migration of cells up from the villus from the crypts

*chemotherapy - stop division of stem cells and sloughed off
what determines length and surface of intestine?
degree of activity and metabolism
spiral valve function
in intestine

increase area and transit time to absorb more
intestine starts to coil in
bony fishes
pyloric caeca
most teleosts have

sometims with special enzymes (ex was lipase)

like hairs in outside of stomach
first appearance of breakdown of seperate sections in intestines
frog and land tetrapods
endotherm intestines
lonter intestine, more folding (lots of vili), greater energy requirements (up to 25x body length in herb mammals but 3.5x in omnivores and carnivores)
colon of mammals function
water recovery and storage of feces
when food enters LI
should already have absorbed food

not lots of villi/microvilli

absorption of wahter

storage of feces to prevent bac infection
herbivores w/o a chambered stomach
horse, rodents,rabbits, etc

have hindgut fermentation where the bacteria lodge

*cows are foregut fermenters
hindgut fermentation
less efficient than foregut fermentation (rumination and transit time 80 hrs)

only get to masticate it once (horse feces and cow dung) and transit time 48 hrs
foregut fermenters
have overall advantage and can survive in low quality areas

eg mountain sheep and goats and camels

better digestion than hindgut
coprophagy
eat their feces

smaller hindgus fermenters undergo

eat 20-60% of feces
liver size
largest organ in body in all vertebrates
lobules
"paving stones" of liver

*ONE MILLION HEPATIC LOBULES IN LIVER
hepatic lobules structure
have hepatic vein and 6 portal triads @ end

blood comes in with portal triad
triad (4 components)
-hepatic portal vein (take food away from liver ot body)
-hepatic artery (bring oxygen blood to keep cell alive)
-bile duct (store bile)
lymphatic
internal structure of hepatic lobule
hepatocytes in rows with sinusoids (where blood drains past) in between
blood cell's view of a sinusoid
gaps between the cells lining the capillary
bile made in..
hepatocytes

leave down bile canaliculi which are small channels between hepatocytes
liver functions(6)
1. exocrine (secretes bile)
2. stores carbs lipids, proteins, vitamins
3. synthesises plasma proteins, lipoproteins
4. metabolizes and detoxifies (drugs, etc)
5. destroys red blood cells and reclaims products
6. site of haematopoiesis in embryo (where blood made)
who has pancreas?
all craniates, but lampreys, teleoosts it is scattered in intestinal wall and mesentary

still do all same functions
2 parts to pancreas
*exocrine (digestion)
*endocrine (islets of langerhans)
exocrine part of pancreas
makes 15 enzymes for digestion

all secreted in proenzyme form and activated in duodenum

typical branched acinar structure

merocrine secretion
centroacinar cell
part of pancreas

secrete bicarb ions to buffer pH to 7
structure of acinus and duct
centroacinar cell
zymogen granules
intercalated duct
excretory duct
islets of langerhans
endocrine

profuse blood supply

ball of cells producing insulin, glucagon, somatostatin, VIP and PP

*rich blood supply
*makes product and put straight into blood
products produced by islets of langerhans
insulin
glucagon
pancreatic polypeptides (PP)
somatostatin