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12 Cards in this Set

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What are the types of measurements in PFT?
Lung volumes-measure maximum volume of lungs as well as sub-compartments; spirometer is common tool
Flow rates-measure the maximal flow of gas out of and into the lung
Diffusing capacity-measures transfer of gas from alveolar space into capillary bloodstream
Maximal inspiratory/expiratory pressures-measure applied strength of respiratory muscles
Volume of air inspired and expired during normal quiet breathing
tidal volume (TV)
The maximum amount of air that can be inhaled after a normal tidal volume inspiration
Inspiratory Reserve Volume (IRV)
Maximum amount of air that can be exhaled from the resting expiratory level
Expiratory Reserve Volume (ERV)
Volume of air remaining in the lungs at the end of maximum expiration
residual volume (RV)
Volume of air that can be exhaled from the lungs after a maximum inspiration
vital capacity (VC)
IRV + TV + ERV
FVC: when VC exhaled forcefully
SVC: when VC is exhaled slowly
Maximum amount of air that can be inhaled from the end of a tidal volume
inspiratory capacity (IC)
IRV + TV
Volume of air remaining in the lungs at the end of a TV expiration
The elastic force of the chest wall is exactly balanced by the elastic force of the lungs
Functional Residual Capacity (FRC)
ERV + RV
Volume of air in the lungs after a maximum inspiration
total lung capacity (TLC)
IRV + TV + ERV + RV
Describe other ways to measure functional residual capacity (FRC)
Helium dilution-Helium is insoluble gas; amount of helium is same before and after equilibrium
Body Plethymograph-At the end of normal expiration, subject is asked to take a deep breath into a body plethymograph box; pressure and volume changes are measured
Describe Fick's Law
Fick's Law: Vgas=(A/T) * D * (P1-P2)
amount of gas transferred is proportional to the area (A), a diffusion constant (D), and the difference in partial pressure (P1-P2); is inversely proportional to the thickness (T)
The constant (D) is proportional to the gas solubility (Sol) but inversely proportional to the square root of its molecular weight (MW)
Describe diffusing capacity
diffusing capacity (Dl)=flow (Vgas)/change in pressure (P1-P2)
CO is a good molecule to use to measure diffusing capacity-because CO binds so tightly to hemoglobin, partial pressure in capillaries is considered zero