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14 Cards in this Set
- Front
- Back
Hyponatremia, the most common electrolyte disorder, is
defined as a reduced plasma sodium concentration to a value less than ____ mEq/L. |
135
|
|
The 4 most common causes of hyponatremia are given, together with a fifth, rare, cause, ______ syndrome.
|
Bartter's
|
|
Schizophrenia causes hyponatremia due to
a) Na+ loss B) water retention |
b
|
|
All confirmed serum Na abnormalities must be
followed up with _____ on the patient who should be fluid restricted. |
urinalysis
|
|
This triad of findings strongly suggests overhydration as
the cause. |
Low HCT
Low BUN low urine osmolality , i.e., < 300 mOsm |
|
Syndrome of Inappropriate ADH
secondary to __________ |
head trauma, seizures,
other CNS diseases, and neoplastic conditions especially lung, breast and ovarian cancers, that secrete ADH-like hormones, |
|
Aldosterone Deficit
This condition is secondary to ____ |
Addison's disease and
AIDS-related hypoadrenalism. |
|
This condition resembles diuretic use except that the
hyponatremia is not corrected with fluid restriction. |
Bartter's Syndrome
|
|
The commonest, yet not widely known, cause of
pseudohyponatremia is in vitro hemolysis, a well-known cause of pseudohyperkalemia. |
Pseudohyponatremia
|
|
Functionally, this condition is the reverse of SIADH,
i.e., water retention in the tubules is not adequate. |
Diabetes insipidus (DI).
|
|
This condition may result from adrenal hyperplasia,
Cushing's syndrome and Cushing's disease. |
Hyperaldosteronism
|
|
Diarrhea causes direct K+ loss in the stool, but in
vomiting hypokalemia is mainly the result of K+ loss in the _____ rather than in the vomitus, since, as discussed above, vomiting causes metabolic alkalosis, and the subsequent renal excretion of bicarbonate leads to renal K+ wasting. |
urine
|
|
Increase in PRA will always lead to increase in PA (20
aldosteronism), unless the rise in PRA is caused by a primary defect in aldosterone secretion. PRA may be high because of: |
volume depletion secondary to renal or extrarenal salt loss
abnormality in renin secretion, e.g., reninoma (hemangiopericytoma of afferent arteriole), malignant hypertension, renal artery stenosis increased renin substrate production, e.g., oral contraceptives. |
|
Causes of Pseudohyperkalemia
|
Thrombocytosis, severe leukocytosis, use of tourniquet with fist exercise, in
vitro hemolysis |