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14 Cards in this Set

  • Front
  • Back
Hyponatremia, the most common electrolyte disorder, is
defined as a reduced plasma sodium concentration to a
value less than ____ mEq/L.
135
The 4 most common causes of hyponatremia are given, together with a fifth, rare, cause, ______ syndrome.
Bartter's
Schizophrenia causes hyponatremia due to
a) Na+ loss
B) water retention
b
All confirmed serum Na abnormalities must be
followed up with _____ on the patient who should
be fluid restricted.
urinalysis
This triad of findings strongly suggests overhydration as
the cause.
Low HCT
Low BUN
low urine osmolality , i.e., < 300 mOsm
Syndrome of Inappropriate ADH
secondary to __________
head trauma, seizures,
other CNS diseases, and neoplastic conditions
especially lung, breast and ovarian cancers, that
secrete ADH-like hormones,
Aldosterone Deficit
This condition is secondary to
____
Addison's disease and
AIDS-related hypoadrenalism.
This condition resembles diuretic use except that the
hyponatremia is not corrected with fluid restriction.
Bartter's Syndrome
The commonest, yet not widely known, cause of
pseudohyponatremia is in vitro hemolysis, a well-known
cause of pseudohyperkalemia.
Pseudohyponatremia
Functionally, this condition is the reverse of SIADH,
i.e., water retention in the tubules is not adequate.
Diabetes insipidus (DI).
This condition may result from adrenal hyperplasia,
Cushing's syndrome and Cushing's disease.
Hyperaldosteronism
Diarrhea causes direct K+ loss in the stool, but in
vomiting hypokalemia is mainly the result of K+ loss in
the _____ rather than in the vomitus, since, as
discussed above, vomiting causes metabolic alkalosis,
and the subsequent renal excretion of bicarbonate
leads to renal K+ wasting.
urine
Increase in PRA will always lead to increase in PA (20
aldosteronism), unless the rise in PRA is caused by a
primary defect in aldosterone secretion. PRA may be high
because of:
volume depletion secondary to renal or extrarenal salt loss
abnormality in renin secretion, e.g., reninoma
(hemangiopericytoma of afferent arteriole), malignant
hypertension, renal artery stenosis
increased renin substrate production, e.g., oral contraceptives.
Causes of Pseudohyperkalemia
Thrombocytosis, severe leukocytosis, use of tourniquet with fist exercise, in
vitro hemolysis