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28 Cards in this Set

  • Front
  • Back
cushing's disease is ... from...
^ ACTH

a pituitary adenoma
cushing's syndrome 3 causes
cushing's disease
ectopic ACTH
adrenal cortisol
ectopic ACTH can come from e.g. 2
small cell lung cancer

bronchial carcinoids
_ --> adrenal ^ cortisol
adenoma
carcinoma
nodular adrenal hyperplasia
^ cortisol --> hypo or hyper glycemia?
hyperglycemia
test re: cushing's syndrome
dexamethasone
dexamethasone suppression test
healthy: v cortisol after low dose

ACTH-producing pituitary tumor:
^ cortisol after low
v cortisol after high

ectopic ACTH-producing tumor, OR cortisol-producing tumor:
^ cortisol after low/high
Conn's syndrome is...
primary hyperaldosteronism (tumor)
_ = acute renal insufficiency
waterhouse-friderichsen syndrome
chronic 1^ adrenal insufficiency is...
addison's disease
addison's disease may be caused by...
adrenal Atrophy

destruction by Atm: autoimmune, TB, metastasis
pheochromocytoma: most tumors secrete (3)
epi
NE
dopamine
urinary _ is elevated in pheochromocytoma

_ in neuroblastoma
urinary VMA

urinary HVA

V is like the Y in pheochromocytoma

H is like the N in neuroblastoma
pheochromocytoma is associated with _
neurofibromatosis

MEN 2A and 2B
Rx for pheochromocytoma
phenoxybenzamine, an irreversible alpha-blocker; followed by surgery
_ is associated with rapid tumor progression of neuroblastoma
N-myc
what kind of myxedema is seen in hypo vs. hyper thyroid?
facial/periorbital

pretibial
hypothyroidism vs. hyperthyroidism at chest & lungs
bradycardia
dyspnea on exertion

chest pain
palpitations
arrhythmias
skin & hair of hypo vs. hyperthyroid
dry; course, brittle

moist; fine
rule of 10's in pheochromocytoma
10% malignant
10% bilateral
10% extra-adrenal
10% calcify
10% kids
10% familial
hashimoto's thyroiditis (7)
--Most common cause of hypothyroidism
--thyrotoxicosis @ rupture
--antithyroglobulin, antimicrosomal ABs
--HLA-DR5
--Hurthle cells
--lymphocytic infiltrate with germinal centers
--moderately enlarged, nontender
cretinism findings: (5)
pot-bellied
pale
puffy-faced
protruding umbilicus
protuberant tongue
subacute thyroiditis is aka _

findings? (5)
de Quervain's

granulomatous inflammation,
^ ESR, jaw pain, early inflammation, very tender thyroid
thyroid replaced by fibrous tissue is aka
Riedel's thyroiditis
Riedel's thyroiditis findings
fixed
hard (rock-like)
painless
subacute thyroiditis is... (3)
self-limited hypothyroidism

often follows a flulike illness

may be hyperthyroid early in course
Graves' is a type _ hypersensitivity
type II
pt. with iodine deficiency is made iodine-replete and --> thyrotoxicosis. phenomenon is called _
Jod-Basedow phenomenon