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28 Cards in this Set
- Front
- Back
cushing's disease is ... from...
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^ ACTH
a pituitary adenoma |
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cushing's syndrome 3 causes
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cushing's disease
ectopic ACTH adrenal cortisol |
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ectopic ACTH can come from e.g. 2
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small cell lung cancer
bronchial carcinoids |
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_ --> adrenal ^ cortisol
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adenoma
carcinoma nodular adrenal hyperplasia |
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^ cortisol --> hypo or hyper glycemia?
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hyperglycemia
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test re: cushing's syndrome
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dexamethasone
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dexamethasone suppression test
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healthy: v cortisol after low dose
ACTH-producing pituitary tumor: ^ cortisol after low v cortisol after high ectopic ACTH-producing tumor, OR cortisol-producing tumor: ^ cortisol after low/high |
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Conn's syndrome is...
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primary hyperaldosteronism (tumor)
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_ = acute renal insufficiency
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waterhouse-friderichsen syndrome
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chronic 1^ adrenal insufficiency is...
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addison's disease
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addison's disease may be caused by...
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adrenal Atrophy
destruction by Atm: autoimmune, TB, metastasis |
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pheochromocytoma: most tumors secrete (3)
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epi
NE dopamine |
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urinary _ is elevated in pheochromocytoma
_ in neuroblastoma |
urinary VMA
urinary HVA V is like the Y in pheochromocytoma H is like the N in neuroblastoma |
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pheochromocytoma is associated with _
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neurofibromatosis
MEN 2A and 2B |
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Rx for pheochromocytoma
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phenoxybenzamine, an irreversible alpha-blocker; followed by surgery
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_ is associated with rapid tumor progression of neuroblastoma
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N-myc
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what kind of myxedema is seen in hypo vs. hyper thyroid?
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facial/periorbital
pretibial |
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hypothyroidism vs. hyperthyroidism at chest & lungs
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bradycardia
dyspnea on exertion chest pain palpitations arrhythmias |
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skin & hair of hypo vs. hyperthyroid
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dry; course, brittle
moist; fine |
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rule of 10's in pheochromocytoma
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10% malignant
10% bilateral 10% extra-adrenal 10% calcify 10% kids 10% familial |
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hashimoto's thyroiditis (7)
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--Most common cause of hypothyroidism
--thyrotoxicosis @ rupture --antithyroglobulin, antimicrosomal ABs --HLA-DR5 --Hurthle cells --lymphocytic infiltrate with germinal centers --moderately enlarged, nontender |
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cretinism findings: (5)
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pot-bellied
pale puffy-faced protruding umbilicus protuberant tongue |
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subacute thyroiditis is aka _
findings? (5) |
de Quervain's
granulomatous inflammation, ^ ESR, jaw pain, early inflammation, very tender thyroid |
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thyroid replaced by fibrous tissue is aka
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Riedel's thyroiditis
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Riedel's thyroiditis findings
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fixed
hard (rock-like) painless |
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subacute thyroiditis is... (3)
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self-limited hypothyroidism
often follows a flulike illness may be hyperthyroid early in course |
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Graves' is a type _ hypersensitivity
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type II
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pt. with iodine deficiency is made iodine-replete and --> thyrotoxicosis. phenomenon is called _
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Jod-Basedow phenomenon
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