Yyyy Parathyroid Hormone

Front 1

PTH is synthesized as a

Back 1

preprohormone

Front 2

In the blood, intact PTH has half-life of

Back 2

<5 minutes.

Front 3

aids in the regulation of calcium and phosphate, having direct action on bone and kidney and indirect action on the intestines through vitamin D.

• ____ increases the serum calcium level by increasing calcium resorption from bone, increasing calcium reabsorption in the renal tubules, and increasing intestinal absorption of calcium by stimulating production of vitamin D

Back 3

PTH

Front 4

Parathyroid glands are composed of

Back 4

chief cells and oxyphil cells

Front 5

. In kidneys, PTH increases calcium reabsorption in the distal tubule and decreases reabsorption of phosphate in the proximal tubule, resulting in _____.

Back 5

phosphaturia

Front 6

Reference range:

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15-65 pg/mL

Front 7

(results in increased blood calcium) may be caused by parathyroid adenoma (tumor), parathyroid carcinoma, or hyperplasia

Back 7

Primary hyperparathyroidism

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may be caused by vitamin D deficiency (presents with low blood calcium levels) or chronic renalfailure

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Secondary hyperparathyroidism

Front 9

(results in decreased calcium and increased phosphate blood levels) may be caused by osteomalacia,autoimmune disease, inborn errors of metabolism, or unintentionalremoval during thyroid surgery.

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Hypoparathyroidism