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39 Cards in this Set
- Front
- Back
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Requires special charcoal containing medium for growth. Uses silver staining and DFA techniques. Requires L-cysteine for it to grow on a medium.
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Legionella pneumophila
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Francisella, brucella, legionella, and pasteurella.
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bacteria requiring cysteine for growth
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usually a waterborne pathogen
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Legionella pneumophila
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headache, dry cough, 25% of cases have abdominal symptoms (diarrhea, abdominal pain, vomiting)
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Legionnaires disease
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how does L. pneumophila invade macrophages?
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2 ways: 1) Porins on the surface of L. pneumophila bind with C3b (which aids in phagocytosis) allowing the cell to go undetected into the macrophage. 2) L. pneumophila has a surface protein named Macrophage invasion potentiator (Mip) which aids in entry into the macrophages.
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best diagnostic tools: DFA + BCYE culture; how effective is DFA by itself?
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Legionnaires disease; not effective-- positive in only 25-50% culture positive cases.
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how do you treat Legionnaires Disease?
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erythromycin and rifampin
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cough, low grade fever, medical student
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Mycoplasmal pneumonia
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Produces mulberry shaped colony in a sterile content media.
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mycoplasma pneumoniae colony
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14 weeks of shedding, cytadhesins, bronchial epithelial cells
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mycoplasma pneumoniae
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cold-agglutin test
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diagnostic for mycoplasma pneumoniae pneumonia
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how do you treat m. pneumoniae pneumonia?
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eryrthomycin and tetracycline or azithromycin and quinolones
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#2 pathogen to cause pneumonia in alcoholics
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klebsiella pneumonia
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non-motile, large capsule, enterobacteria, mucoid colony
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klebsiella pneumonia
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jumping gene
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Klebsiella pneumonia
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Red gelantinous sputum
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Klebsiella pneumonia
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forms lung abscesses, interferes with phagocytosis, leaves residue behind on CT even after treatment
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Klebsiella pneumonia
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How do you treat Klesiella pneumonia?
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Tx: ciprofloxacin or combo of cephalosporin and aminoglucosides.
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Fruity odor and striking green color
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Pseudomonas aeruginosa
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oxidase positive distinguishing it from enterobacteriaceae
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pseudomonas aeruginosa
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alignate and mutates LPS and porin proteins
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pseudomonas aeruginosa
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Two most popular underlying diseases to contract p. aeruginosa
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CF and burn victims.
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what does alignate serve as?
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microbial barrier
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what is the tx for P. aeruginosa?
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B-lactam antibiotics specifically anti-pseudomonal penicillins: carbenicillin, piperacillin, ticracillin.
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#1 cause of PID
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Chlamydia pneumoniae
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has an elementary body as the infective form and a reticular body as the intracellular form.
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Chlamydia
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Tx for chlamydia pneumonia
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Tx: macrolides (erythromycin, clarithromycin, azithromycin), tetracycline (doxycycline), and levofloxacin.
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what pathogen is associated with atherosclerosis?
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C. pneumoniae
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spenomegaly, birds, and pneumonia
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C. Psittaci
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How do you tx: C. Psittaci Pneumonia?
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Tx: macrolide and tetracycline.
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What is the pathogen?
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Pseudomonas aeruginosa
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what is this? what pathogen does it belong to?
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elementary body of C. psittaci
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what is it? what pathogen does it belong to?
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elementary bodies of Chlamydia pneumoniae
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what is it? what kind of agar is it on?
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Klebsiella Pneumoniae on Macconkey agar
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what is it and what medium is it on?
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L. pneumophila on BCYE agar
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what is the name of this pathogen? what is it stained with?
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L. pneumophila stained with Direct Flourescent antibody.
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diagnosis
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mycoplasma pneumonia pneumonia
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what is this pathogen?
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mycoplasma pneumoniae
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what is this pathogen? where is it located?
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P. aeruginosa in the blood
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