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98 Cards in this Set
- Front
- Back
Fe, b12, Folic Acid, or a combination of these would cause what anemia?
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Factor deficiency anemia
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Failure of blood forming organs to produce or delivery mature RBC's?
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Product defect anemia
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Fe absorption is increased by?
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Vit C, 45 min before eating food
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Fe absorption is decreased by?
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Coffee, tea, dairy products, and foods with high fiber content.
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True or false, iron is absorbed in human milk better than its absorbed in cows milk?
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True
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Primary storage form of iron is?
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Ferritin
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Most common cause of anemia?
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Bleeding
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Gold standard for iron deficiency anemia?
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Bone marrow becomes deficient first, then serum iron decreases next.
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RDW & Fe deficient anemia?
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RDW increases
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More sensitive test for iron deficiency than bone marrow?
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Serum ferritin
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decresed MCV & increased RDW?
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chronic iron deficiency
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decreased SI & decreased TIBC suggest ?
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Chronic Dz
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decreased SI & Increased TIBC suggest?
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Acute Fe deficiency
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Decreased SI & decreased %TS suggest?
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Thalassemia minor
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Large doses of what can make B12 appear low?
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Vit C
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Functional test for B12 deficiency
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Methyl Malonic Acid (MMA)
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definitive test for PA?
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Schilling test
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Folic acid deficiency test causes megaloblastic anemia indistinguishable from PA, EXCEPT FOR?
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Schilling test
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Pyridoxine deficiency is classified as?
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Sideroblastic anemia, resembling a chronic Fe deficiency
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T of F Retics are usually decreased for lab tests of hemolytic anemia?
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F usually increased
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Hemolytic anemia LDH, tell me about it!
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LDH-elevated LDH-1/LDH-2 ratio is usually reversed
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A sign for significant hemolysis
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Free hemoglobin in plasma or urine
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Hb A1
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Normal Hb with 1alpha & 1beta chain
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Hb A2
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2 Alpha & 2 Delta chain
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Thalassemia major, mediterranean origin; hypochromic nucleated Rbc's, decreased Hb A1 and increased Hb F?
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Coolet's Anemia
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Abetalipoproteinemia?
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Bassen Kornsweig Syndrome
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Acute Nonlymphocytic Leukemia AKA Acute myeloproliferative Leukemia; all involve what? and are characterized by what?
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Lymphocytes; characterized by pancytopenia
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M/C malignant Dz in children is ?
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ALL
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ALL is most common in children btw the ages of what?
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2-10
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Most common leukemia in the western hemisphere?
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CLL, Virl >50YOA
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2 age peeks; Reed sternberg cells; may be a mediastinal mass?
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Hodgkin's disease
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Caloric study used to evaluate what CN and which part of brain?
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CN VIII, temporal lobe
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Contraindications to caloric study
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Perforated eardrum and meinier's syndrome
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Cold water uses rotary nystagmus away or towards irrigated ear?
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Away, COWS= cold opposite, warm same
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hot water causes rotary nystagmus away or towards irrigated ear?
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towards
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Pt will experience what two things during caloric study?
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Nausea and dizziness, do not perform on an empty stomach
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Which ear should be tested first during caloric study?
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The suspected side
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If no symptoms occur in the caloric study, how many min should it be stopped?
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3
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After how many min after the first test on the caloric study should you test the other side?
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5
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What is recommended that the patient do after the caloric study test?
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Bed rest
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What is a normal finding in the cardiac stress test?
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Able to maintain 85% of max heart rate
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How is heart stressed if exercise is not safe for patient?
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Drugs
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What are some interfering factors concerning the cardiac stress test?
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Heavy meals, nicotine before test
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During the cardiac stress test, nicotine causes the heart to?
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Spasm
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Cardiac stress test can help identify?
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Coronary artery occlusive disease
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Manometry is the measurement of what?
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Pressure (bladder, LES, arteries, veins, urethra)
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What can be introduced into the the stomach and the esophagus for testing?
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Dilute Acid (HCL)
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What is a normal finding for acid clearing w/ esophageal manometry?
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<10 swallows
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Which test has dilute acid and saline solution alternately introduced?
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Bernstein test
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What is it called when their is an absence of tone in the LES allows reflux of gastric contents?
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Chalasia
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What is a common cause of vomiting in newborns?
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Chalasia
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What is it called when the LES does not relax and obstructs the passage of food into the mouth?
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Achalasia
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What is it called when the LES pressure is low, allowing stomach contents to enter the esophagus, causing irritation and inflammation?
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Gastroesophageal reflex and reflux esophagitis
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What can arterial plethysmography be used for to rule out?
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Malingering
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What is done to a pt with arterial plethysmography?
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reproduce pain, an increase in measured results.
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Malingering is ruled out if the rate and amplitude are significantly what?
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Increased
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What does the tourniquet test evaluate for?
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Caplillary fragility and platelet disorders
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What are the normal findings for the tourniquet test?
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<2 petechiae
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In one of two methods, a BP cuff is inflated to what? How long?
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70mmhg for 5 mins, other method is suction cup applied to skin for 1 min.
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Blood smear culture and sensitivity is used to detect the presence or absence of what in the blood?
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Bacteria
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If a patient is currently taking antibiotics, when should the specimen be drawn, before or after you take the next dose?
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Before you take the next dose
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Venipuncture for blood smear culture and sensitivity, must 1st clean with ?
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Bentadine
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Rbc color abnormalities: what is associated with iron def, thalassemia or heart disease?
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Hypochromia
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RBC color abnormalities: what is associated with concentrated hemoglobin usually casued by dehydration?
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Hyperchromia
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When you see howell-jolly bodies, what types of diseases do you expect?
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Hemolytic anemia, megaloblastic anemia
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What do they call particles of hemoglobin?
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Heinz bodies
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A bone marrow biopsy is used to confirm what diagnosis?
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Megoblastic anemia
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PaP smear is 95% accurate for what diagnosis?
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Cervical cancer
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a pap smear is 40% accurate for what type of cancer?
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endometrial
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Cell classification class 1?
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Normal cells
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Cell classification class 2?
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Atypical, usually caused by inflammation
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Cell classification class 3?
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Malignancy, but not conclusive
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Cell classification class 4?
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strongly suggestive of malignancy.
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Cell classification class 5?
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Conclusive of malignancy
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What system was developed by the national cancer institute?
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Bethesda
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A stool culture is used to identify what?
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bacteria and parasites
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Occult blood in a stool test?
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Gi cancer, peptic disease, VARICIES, ulcerative colitis, crohns
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Interfering factors for a stool test are?
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MEAT, turnips, horse radish, bleeding gums
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Serum bilirubin is a break down product of what?
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Hemoglobin
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Unconjugated bilirubin binds with _____ and is carried to the _____?
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Albumin, liver
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After unconjugated bilirubin is conjugated in the liver it goes where?
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Excreted in the bile
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Jaundice is a visible staining of the tissues with what?
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Bilirubin
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What is one of the causes of jaundice?
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Hemolysis
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During hemolysis what happens to the serum unconjugated bilirubin?
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increased
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During hemolysis what happens to serum conjugated bilirubin?
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Remains normal
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During obstructive jaundice serum conjugated bilirubin initially ____unconjugated bilirubin?
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Exceeds, after several days the ratio approaches 1:1
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How can you differentiate between bone ALP and liver ALP?
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Jaundice indicates part is from liver. Electrophoresis is more reliable
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A ratio of >1 for AST/ALT is considered a _____sign and can be related to alcohol cirrhosis, liver congestion, metastatic tumor?
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>1 Serious sign
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What usually elevates ALT
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Liver disease
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PT is dependent on what vitamin?
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Vitamin K
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The most common cause of abnormal PT is what>
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Liver DZ, decrease bile salts, dec Vit K,
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Which level of bile acid assays more sensitive than fasting level?
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2 hour post prandial (after you have eaten)
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What type of serum ptn decreases with liver dysfunction
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albumen
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hepatitis is associated with levels of what?
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gamma globulin
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biliary obstruction is associated with levels of what?
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Beta globulin
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Urea is formed in the liver from various sources of ammonia that come mostly from where?
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Protein splitting bacteria in the GI tract
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What is common to see in lab findings of acute viral hepatitis?
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Leukopenia and relative lymphocytosis & atypical lymphocytes
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With acute cholecystitis what lab findings MAY you see?
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Increased Serum amylase
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