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13 Cards in this Set

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what makes an enzyme an ABC enzyme:
ATP utilization
Biotin is a required cofactor
C is for carboxylation
pyruvate carboxylase catalyzes the reaction ...
pyruvate --> oxaloacetate
in the insulin world ... is used to make fatty acids and it is pulled out of the tca cycle which makes a build up of ... this build up turns ... (enzyme) 'off' and ... (enzyme) 'on' which puts ... back into the system
citrate
acetyl CoA
pyruvate dehydrogenase
pyruvate carboxylase
4C molecule
in the glucagon world, we have ... from fatty acid breakdown and this turns 'off' ... and turns 'on' ...

we do gluconeogenesis and get the precursor ... from the tca cycle
acetyl CoA
pyruvate dehydrogenase
pyruvate carboxylase
malate
in gluconeogenesis, where do we get the pyruvate from?
amino acids
what does the following describe:

An enzyme-catalyzed chemical reaction that recharges the supply of intermediate molecules in various metabolic reactions such as the citric acid cycle.
anaplerotic pathway/reaction
tca cycle (is/is not) under hormonal regulation:
is not
the first irreversible step in the tca cycle is ... and is regulated by:
1.
2.
3.
isocitrate --> alpha-ketoglutarate via isocitrate dehydrogenase
1. ADP (+)
2. NADH (-)
3. Ca2+ (+)
if i am in an energy poor state i have plenty of ...

if i am in an energy rich state i have plenty of ...
ADP
NADH
when you have decarboxylation you are generating ...
NADH
what are the 5 cofactors for pyruvate dehydrogenase:
1.
2.
3.
4.
5.
1. NADH
2. FADH (riboflavin)
3. lipoate/lipoic acid
4. thiamine (B1)
5. CoASH/Coenzyme A (panthothenic acid)
1. NADH
2. FADH (riboflavin)
3. lipoate/lipoic acid
4. thiamine (B1)
5. CoASH/Coenzyme A (panthothenic acid)

are coenzymes for pyruvate dehydrogenase and ...
alpha-ketoglutarate dehydrogenase
1. what activates pyruvate dehydrogenase? 2. and what inactivates pyruvate dehydrogenase?
1. Ca++, ADP, pyruvate
2. acetyl CoA, NADH