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23 Cards in this Set
- Front
- Back
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where are 6 of the 8 enzymes of the TCA cycle located?
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matrix
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2 of the 8 enzymes of the TCA cycle that are not located in the matrix are located where? And what are these 2 enzymes:
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imbeded in the inner mitochondrial membrane
succinate dehydrogenase alpha-ketoglutarate dehydrogenase |
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where is ATP synthase located:
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imbeded in the inner mitochondrial membrane
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where is pyruvate dehydrogenase located?
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imbeded in the inner mitochondrial membrane
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identify the precursors that get metabolized to acetyl-CoA:
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(see figure)
acetate glucose pyruvate fatty acids ketone bodies amino acids |
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biosynthetic work (can/cannot) be done in the mitochondria
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cannot
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sugar can be made from fatty acids (true/false)
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false
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identify the number of carbons in each intermediate of the cylcle:
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(see figure)
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where is GTP produced in the cell
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TCA cycle: succinyl CoA --> succinate
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the process of making GTP from GDP is called …
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substrate level phosphorylation
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identify the enzymes in the TCA cycle:
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(see figure)
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what is the overall energy yield in the TCA cycle:
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3 NADH
1 FADH 1 GTP |
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where is the FADH produced in the TCA cycle:
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succinate --> fumarate
(catalyzed by succinate dehydrogenase) |
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where are the 3 NADH's produced in the TCA cycle:
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isocitrate --> alpha-ketoglutarate
alpha-ketoglutarate --> succinyl CoA malate --> oxaloacetate |
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where do the 2 CO2 from Acetyl CoA leave the TCA cycle:
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isocitrate --> alpha-ketoglutarate
alpha-ketoglutarate --> succinyl CoA |
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what are the energy values for each box:
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(see figure)
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citrate is a TCA intermediate and can be synthesized into …
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fatty acids
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alpha-ketoglutarate is a TCA intermediate and can be synthesized into …
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amino acids and neurotransmitters
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succinyl CoA is a TCA intermediate and can be synthesized into …
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heme
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malate is a TCA intermediate and can be synthesized into …
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glucose via gluconeogenesis
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oxaloacetate is a TCA intermediate and can be synthesized into …
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amino acids
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pyruvate carboxylase is active in the (glucagon/insulin) world
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both
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the amino acid ... can be easily converted into pyruvate
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alanine
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