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23 Cards in this Set

  • Front
  • Back
where are 6 of the 8 enzymes of the TCA cycle located?
matrix
2 of the 8 enzymes of the TCA cycle that are not located in the matrix are located where? And what are these 2 enzymes:
imbeded in the inner mitochondrial membrane
succinate dehydrogenase
alpha-ketoglutarate dehydrogenase
where is ATP synthase located:
imbeded in the inner mitochondrial membrane
where is pyruvate dehydrogenase located?
imbeded in the inner mitochondrial membrane
identify the precursors that get metabolized to acetyl-CoA:
(see figure)
acetate
glucose
pyruvate
fatty acids
ketone bodies
amino acids
biosynthetic work (can/cannot) be done in the mitochondria
cannot
sugar can be made from fatty acids (true/false)
false
identify the number of carbons in each intermediate of the cylcle:
(see figure)
where is GTP produced in the cell
TCA cycle: succinyl CoA --> succinate
the process of making GTP from GDP is called …
substrate level phosphorylation
identify the enzymes in the TCA cycle:
(see figure)
what is the overall energy yield in the TCA cycle:
3 NADH
1 FADH
1 GTP
where is the FADH produced in the TCA cycle:
succinate --> fumarate
(catalyzed by succinate dehydrogenase)
where are the 3 NADH's produced in the TCA cycle:
isocitrate --> alpha-ketoglutarate
alpha-ketoglutarate --> succinyl CoA
malate --> oxaloacetate
where do the 2 CO2 from Acetyl CoA leave the TCA cycle:
isocitrate --> alpha-ketoglutarate
alpha-ketoglutarate --> succinyl CoA
what are the energy values for each box:
(see figure)
citrate is a TCA intermediate and can be synthesized into …
fatty acids
alpha-ketoglutarate is a TCA intermediate and can be synthesized into …
amino acids and neurotransmitters
succinyl CoA is a TCA intermediate and can be synthesized into …
heme
malate is a TCA intermediate and can be synthesized into …
glucose via gluconeogenesis
oxaloacetate is a TCA intermediate and can be synthesized into …
amino acids
pyruvate carboxylase is active in the (glucagon/insulin) world
both
the amino acid ... can be easily converted into pyruvate
alanine