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67 Cards in this Set
- Front
- Back
The intricate structure of the heart develops during the fist ___ of life
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eight weeks
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From what type of tissue does the heart develop:
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mesoderm
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When does the heart begin to beat:
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on the 22nd day
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Where does the heart start forming:
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rostral to the oral plate, adjacent to the septum transversum
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what happens on day 18 in the development of the heart:
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small islands of blood and endothelial tissue begin to differentiate out of the mesoderm
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When does blood and endothelial tissue begin to differentiate out of the mesoderm:
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day 18
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blood islands unite to form ___ shaped tube when during embryonic development: (what day)
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horseshoe
days 18-19 |
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what happens in the embryo heart in days 21-22: (x2)
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Venous end receives blood from yolk sac
(body’s first functional veins) Arteries begin to pump to the head, via early aortic arches |
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identify the structures:
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(see figure)
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As the heart grows why does it bend into an ‘S’ shape:
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the heart grows at a faster rate than the pericardial cavity
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The heart grows at a faster rate than the pericardial cavity, what is the result:
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it bends into an ‘S’ shape
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what is the name of the bulge in the 'S' shaped heart:
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bulboventricular loop
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identify the labeled structures:
embryonic heart age: |
(see figure)
6th week |
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identify the labeled structures:
age of the embryonic heart: |
(see figure)
8-9 weeks |
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As the heart develops, systemic veins move to drain into the ___ side of heart, systemic arteries move to arise from the ___ side of heart
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right
left |
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how do the developing embryonic atria fuse and expand:
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by incorporating veins into atrial walls
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The rough-walled part of the atrium comes from ___ while the smooth-walled (sinus venarum) part comes from ___
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embryonic atrium
venous origin |
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the __ develops in the center of the single atrial and ventricular cavity from ant. to post.
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endocardial cushion
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the ___ initially separates the 2 atria but there is open communication via the ___
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septum primum
foramen primum |
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during embryonic development, the ___ separates the 2 ventricles and the ___ is the opening between them
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interventricular septum
interventricular foramen |
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As foramen primum shrinks, a second foramen connecting the two atria forms called ___ and a second septum froms called the ___
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foramen secondum
septum secondum |
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what happens in the final separation of the atria and ventricles: (x3)
(what's closed/open) |
1. atria leave an opening called the foramen ovale
2. interventricular septum closes 3. truncus arteriosus closes |
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what is the function of the foramen ovale:
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for blood to go from the IVC to the L. atrium
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when the interventricular septum closes the membranous part arise from what:
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endocardial cushion
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the truncus arteriosus closes with a ___, separating the ___ from the ___
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spiral septum
aorta pulmonary trunk |
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in the fetus, SVC carries (high/low) oxygen blood from where:
IVC carries (high/low) oxygen blood from where: |
low
head and upper limb high umbilical vein |
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how is blood routed through the right atrium from SCV:
IVC: |
SVC blood goes directly through right atrium to right ventricle
IVC blood goes through foramen ovale to left atrium, and hence to left ventricle |
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the two Aorta and Pulmonary trunk separate out from a common truncus by means of a ___
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spiral septum
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the right ventricle is anterior, while the pulmonary trunk has to arise from the ___ of the aortic sac
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posterior part
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the left ventricle is posterior, while its Aorta has to arise from the ___ of the aortic sac
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anterior part
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The final result of the spiral septum is what:
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aorta and pulmonary trunk that twist around each other
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what are the great vessels:
from where do they arise: |
aorta and pulmonary trunk
aortic arches |
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what are the aortic arches that develop in the human embryo:
arches ___ involute early, and leave no major remnant |
1,2,3,4,and 6
1 and 2 |
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what is the function of the umbilical artery:
what is the function of the vitelline artery: |
supply deoxygenated blood from the fetus to the placenta
an artery carrying blood to the yolk sac from the embryo |
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___ that is high in O2 brings blood back from the maternal circulation and continues up to the liver as the ___ where it meets up with the ___ that is low in O2
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umbilical vein
ductus venosus portal vein |
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the ___ is brining some low O2 content blood from the GI tract up to the liver where it mixes with the high O2 blood from the ___ to form the ___
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portal vein
ductus venosus inferior vena cava |
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the ___ is brining fairly high O2 content blood to the right atrium, where the majority of the blood with squirt through the ___ into the ___
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inferior vena cava
foramen ovale left atrium |
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from the left atrium, the blood will go to the ___ and out the ___ and to the rest of the body from there
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left ventricle
aorta |
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the ___ brings low O2 blood from the body and brings it in to the ___ where it then goes to the ___ and then out the ___
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superior vena cava
right atrium right ventricle pulmonary trunk |
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the lungs aren't working yet so the blood from the ___ goes through the ___ and mixes with the aortic blood where it feeds all the tissues of the body and then leaves the body through the ___
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pulmonary trunk
ductus arteriosus umbilical arteries |
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what causes the foramen ovale to close: (4 steps)
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1. stopping of umbilical circulation
2. (↓)IVC blood flow causing (↓)right atrial pressure 3. blood flows to expanding lungs through pulmonary circulation 4. (↑)blood flow to left ventricle |
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___ and other factors cause smooth muscle in ductus arteriosus and ductus venosus to contract, sealing off these ducts
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oxygen tension
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atrial septal defects occur in the ___ and allow what:
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interatrial wall
mixing of blood between left and right atria |
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what is a probe-patent foramen ovale:
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minor atrial septal defect
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what is a high atrial septal defect:
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hole up near the SVC, connecting the two atria
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a typical atrial septum defect is caused by either 1 of 2 things:
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1. too large of a foramen secundum
2. too large a fossa (foramen) ovalis |
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what is the cause of a septum primum defect:
what is the result of this defect: |
failure of septum primum to completely fuse with endocardial cushion
a variably sized hole connecting the two atria |
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This septum defect is frequently found in patients with Down’s syndrome:
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septum primum defect
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what is the cause of the membranous ventricular septal defect:
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failure of fusion of the interventricular septum with the endocardial cushion
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(atrial/ventricular) septum defects are the most common:
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ventricular
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(membranous/muscular) septal defects are less common:
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muscular
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what are truncus defects caused by:
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failure of the spiral septum of the truncus arteriosus
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what are the affected structures in truncus defects: (x3)
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ascending aorta
pulmonary trunk semilunar valves |
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what is the cause of persistent truncus arteriousus:
what is the result in the newborn: |
failure for truncus to separate at all
no separation of blood flows no aortic or pulmonary valves |
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what is occurring in the defect transposition of great vessels: (x3)
why does this occur: |
right ventricle pumps to aorta
left ventricle pumps to pulmonary trunk no transfer of oxygen to systemic circulation spiral septum is straight and not spiral |
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what is occurring in unequal division:
what does this usually involve so that a baby could survive: |
one vessel has a large opening, the other is small (aorta/pulmonary trunk)
a VSD so rest of right ventricular blood can get into aorta |
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what is occurring in tetralogy of fallot:
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1. pulmonary stenosis
2. VSD (ventricular septal defect) 3. Over-riding aorta (aorta sits right over the interventricular septum, collecting blood from both ventricles) 4. hypertrophy of right ventricle |
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what is ectopia cordis:
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failure of sternum to fuse, producing a heart outside of the thoracic cavity
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what is dextrocardia:
when is this not a big problem: |
reverse rotation
situs inversus |
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what is persistent ductus arteriosus:
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pulmonary by-pass to continues functioning
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what is occurring in ductus arteriosus: (think pressure)
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Flow reverses, so blood going from high pressure to low → goes from aorta to pulmonary trunk (with resulting pulmonary hypertension).
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what is coarctation of the aorta:
what are the 2 forms: |
inexplicable narrowing of the aorta near the ductus arteriosus
preductal forms and postductal forms |
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what is occurring in coarctation of the aorta: (blood pressure)
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blood pressure to upper extremities is increased
blood pressure to lower extremities is minimal. |
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how do you detect coarctation of the aorta:
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compare brachial pulse to femoral pulse in newborn
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in coarctation of the aorta:
in which form does ductus arteriosus act to supply low-oxygen blood to lower extremities |
preductal form
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in coarctation of the aorta:
in which form does blood from aorta use ductus arteriosus as pressure relief valve: |
postductal forms
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what happens if blood from the aorta uses ductus arteriosus as a pressure valve:
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pulmonary hypertension
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