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33 Cards in this Set

  • Front
  • Back
what does it mean if a wound is contaminated?
non-replicating microbes are present
what is colonization?
replicating microbes are present s a host response
what is an infection?
where replicating microbes invade viable tissue
how many microbes are needed to create an infection in general
10^5/g
what are the effects of an infection?
maintain inflammatory phase
increased metabolic demand
tissue necrosis
risk of abscess
what are factors in prognosis of wounds?
# of microbes
Virulence
host resistance
what is the # of microbes referred to?
Bioburden
what is Virulence
how toxic the microbe is

the # of microbes or amt of toxin that is lethal
what is an abscess?
where do they often occur?
an area of localized infection that has been walled off but the body cannot get rid of

under skin (tunneled)
as long as microbes are present what will occur?
inflammatory phase
what are causes of tissue necrosis with infections?
bodies own inflammatory response kills some tissue

bacteria secrete exotoxins &/or endotoxins which could be cytotoxic
what are forms of infection control?
universal precautions
standard precautions
hand washing
following damn directions
sterile tech.
clean tech.
when would you want to use a sterile technique?
packing (deep/tunneling wounds)
large wounds
burns
immunosupression
sharp debridement
why would you use sterile technique for deep wounds/tunneling wounds?
burns?
deep-if things start to go bad you can not see signs of infection

burns-dendritic & langerhan cells are destroyed so person is immunosuppressed.
what is the presentation of an infected wound?
S/S of inflammation are out of proportion to expectations

extensive, poorly defined periwound erythema

streaking

increased elevation of temp

increased viscosity and purulence

increased odors p cleansing
what is viscosity composed of?
an increase of dead cells and protiens which causes fluid accumulation
what is purulence?
milky pussy looking substance made up of dead white blood cells
why is fluid aspiration risky?
could drive the microbe form surface deeper into wound causing tunneling
what is the gold standard of wound cultures?
tissue Bx
what are 2 reasons swabbing may not be appropriate?
bacteria may not be on surface

cotton could stay in in wound & be treated as a foreign invader
what is osteomyelitis?
what is a common mechanism?
inflammation of bone or bone marrow

Staph Aureus (esp MRSA)
when must you assume someone has osteomyelitis?

what must you do?
if you can see or touch bone

prevent wound from closing
what is contraindicated for osteomyelitis? why?
e-stim b/c there is no evidence it will help bone and it will promote wound closure.
What would you expect if an antibiotic made a wound worse? why?
may be a fungal infection b/c the Abx kills the "good" bacteria and hinders immune function
what are two resistant strains of bacteria?
MRSA
VRE
what is the problem with antiseptics?
they are generally cytotoxic and kill healthy/healing tissue as well as immune cells
when may you use an antiseptic?
short-term if the wound is multi-microbial
what does debridement do?
remove necrotic tissue
what are the problems c necrotic tissue in a wound?
breeding ground for microbes
lowers wound O2
occupies host cells that try to clean it up
blocks granulation & epithelialization
What are two bacteriocidal /bacteriostatic modalities used for wounds?
e-stim
UV light
what kind of e-stim is used for wounds?
cathodal pulsed, Hi-Volt, or DC
what is the planktonic model?
microbs are fee floating
these is minimal glycocalx
& bacteria are susceptible to Abx
what does lactoferrin do?
binds up iron so microbes can't use it