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33 Cards in this Set
- Front
- Back
what does it mean if a wound is contaminated?
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non-replicating microbes are present
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what is colonization?
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replicating microbes are present s a host response
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what is an infection?
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where replicating microbes invade viable tissue
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how many microbes are needed to create an infection in general
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10^5/g
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what are the effects of an infection?
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maintain inflammatory phase
increased metabolic demand tissue necrosis risk of abscess |
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what are factors in prognosis of wounds?
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# of microbes
Virulence host resistance |
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what is the # of microbes referred to?
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Bioburden
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what is Virulence
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how toxic the microbe is
the # of microbes or amt of toxin that is lethal |
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what is an abscess?
where do they often occur? |
an area of localized infection that has been walled off but the body cannot get rid of
under skin (tunneled) |
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as long as microbes are present what will occur?
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inflammatory phase
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what are causes of tissue necrosis with infections?
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bodies own inflammatory response kills some tissue
bacteria secrete exotoxins &/or endotoxins which could be cytotoxic |
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what are forms of infection control?
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universal precautions
standard precautions hand washing following damn directions sterile tech. clean tech. |
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when would you want to use a sterile technique?
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packing (deep/tunneling wounds)
large wounds burns immunosupression sharp debridement |
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why would you use sterile technique for deep wounds/tunneling wounds?
burns? |
deep-if things start to go bad you can not see signs of infection
burns-dendritic & langerhan cells are destroyed so person is immunosuppressed. |
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what is the presentation of an infected wound?
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S/S of inflammation are out of proportion to expectations
extensive, poorly defined periwound erythema streaking increased elevation of temp increased viscosity and purulence increased odors p cleansing |
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what is viscosity composed of?
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an increase of dead cells and protiens which causes fluid accumulation
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what is purulence?
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milky pussy looking substance made up of dead white blood cells
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why is fluid aspiration risky?
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could drive the microbe form surface deeper into wound causing tunneling
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what is the gold standard of wound cultures?
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tissue Bx
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what are 2 reasons swabbing may not be appropriate?
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bacteria may not be on surface
cotton could stay in in wound & be treated as a foreign invader |
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what is osteomyelitis?
what is a common mechanism? |
inflammation of bone or bone marrow
Staph Aureus (esp MRSA) |
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when must you assume someone has osteomyelitis?
what must you do? |
if you can see or touch bone
prevent wound from closing |
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what is contraindicated for osteomyelitis? why?
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e-stim b/c there is no evidence it will help bone and it will promote wound closure.
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What would you expect if an antibiotic made a wound worse? why?
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may be a fungal infection b/c the Abx kills the "good" bacteria and hinders immune function
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what are two resistant strains of bacteria?
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MRSA
VRE |
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what is the problem with antiseptics?
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they are generally cytotoxic and kill healthy/healing tissue as well as immune cells
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when may you use an antiseptic?
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short-term if the wound is multi-microbial
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what does debridement do?
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remove necrotic tissue
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what are the problems c necrotic tissue in a wound?
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breeding ground for microbes
lowers wound O2 occupies host cells that try to clean it up blocks granulation & epithelialization |
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What are two bacteriocidal /bacteriostatic modalities used for wounds?
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e-stim
UV light |
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what kind of e-stim is used for wounds?
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cathodal pulsed, Hi-Volt, or DC
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what is the planktonic model?
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microbs are fee floating
these is minimal glycocalx & bacteria are susceptible to Abx |
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what does lactoferrin do?
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binds up iron so microbes can't use it
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