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33 Cards in this Set

  • Front
  • Back
Cell death caused by a blockage of the oxygen supply to the injured area or caused by enzymatic damage and mitochondrial failure
Secondary damage
natural response to an injury through which dead or lost tissue is replaced by living tissue.
Tissue Healing
Most abundant type of tissue in the body.
Produced by fibroblasts
Connective tissue
The predominant type of connective tissue
Collagen
Secretes extracellular matrix components
Fibroblasts
Produces extracellular matrix components in cartilage
Chondrocytes
Produces extracellular matrix components with contractile properties
Myofibroblasts
Stores lipids
Adipocytes
Responsible for transferring physical loads of force
Deep fascia
An excessive accumulation of serous fluids.
Edema
Delicate tissue composed of fibroblasts, collagen, and capillaries formed during the revascularization phase of wound healing
Granulation tissue
Bleeding, from veins, arteries, or capillaries
Hemorrhage
A blood-thinning chemical released from damaged tissue during the inflammatory process. Its primary function is vasodilation of arterioles and increased vascular permeability in venules
Histamine
Local and temporary deficiency of blood supply caused by obstruction of circulation to a part.
Ischemia
Chemicals that act through indirect means
Mediators
A classification of scavenger cells that ingest and destroy unwanted substances in the body.
Phagocyte
A protein based connective tissue
Collagen
A cell concerned with the formation of new bone
Osteoblast
A cell that absorbs and removes unwanted bone
Osteoclast
A nerve that provides impulses to muscles
Motor nerve
A group of skeletal muscle fibers that are innervated by a single motor nerve
Motor Unit
Carrying impulses toward a central structure,the brain.
Afferent
Carrying impulses away from a central stucture. Nerves leaving the CNS.
Efferent
Dominate the first 6 to 24 hours of phagocytosis, releasing chemical "cluster bombs" that are intended to destroy bacteria but end up traumatizing all tissues in the area
Neutrophils
-Mechanism designed to rid the body of damaged tissue
-It is an immediate response to acute injuries
-It is non-specific to site or stimulus
-Essential for tissue repair
What is the inflammatory response?
fibroblastic-repair, fibroplasia (scar formation))
Proliferation
(maturation-repair, remodeling (scar maturation))
Maturation
-Short onset and duration
-Hemodynamic changes
-Production of exudate -Presence of granular leukocytes
-More extensive formation of scar tissue
Acute inflammation
-Occurs when the acute inflammatory response does not eliminate the injurious agent
-Longer onset & duration
-Displays the replacement of leukocytes with macrophages, lymphocytes, & plasma cells
Chronic Inflammation
-Trauma followed by transient vasoconstriction to control hemorrhaging
First process of acute inflammation
-Vasodilatation and increased blood flow
-Coinciding with these vascular changes in an increase in vascular permeability
Second stage of acute inflammation
- Gaps then occur in the cell walls increase the intravascular hydrostatic pressure (IHP) which causes fluid to filtrate out into the interstitial space
-Fluid accumulates, causing edema (clinical manifestation of increase in vascular permeability)
Third stage of acute inflammation
-Trauma followed by vasoconstriction of capillaries, venules, and arterioles and = decrease in blood flow (transient)
-Occurs as norepinephrine is released into the tissue to prevent blood loss to the affected area
Stage 1 Inflammation