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Drugs affecting wound healing

Drugs affecting wound healing

Nicorandil and hydroxyurea

Directly cause ulceration

Drugs affecting my wound healing

Methotrexate

Decrease so mitosis, increase infection risk

Drugs affecting my wound healing

Steriods

Decrease DNA synthesis, Suppress inflammatory response, increase infection risk

Drugs affecting my wound healing

Immunosuppressants

Decreased neutrophil/microfiche activity

Drugs affecting my wound healing

Aspirin/warfarin

Can affect coagulation cascade

Drugs affecting my wound healing

Calcium channel blocker

Oedema

Drugs affecting my wound healing

Beta-blockers

Can cause very personal way so constriction

Drugs affecting my wound healing

Nicorandil

Vasodilatory drug used to treat angina


Nicorandil stimulates guanylate cyclase to increase formation of cyclic GMP

Hydroxyurea

Antimetabolite- anti-cancer for sickle-cell anaemia.