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33 Cards in this Set
- Front
- Back
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wound in which involves only the epidermis
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superficial wound
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wound in which involves the dermis and epidermis
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Partial-thickness
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wound which is deeper then the dermis
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Full-thickness
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Depth is often related to as _______
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Staging
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Physiologic response to wounding is associated with the ______
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Phase
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Primary closure
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physical approximation of wound edges, following debridement as needed
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Secondary closure is needed when
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edges can't be approximated d/t size, infection, tissue quality, ect
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In which type of closure can dehiscence occur?
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both
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more granulation and wound contraction is needed in which type of closure
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Secondary
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what are two likely causes of dehiscence?
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-poor tissue quality
-edema |
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Name two reasons skin grafts are not used in chronic wounds
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-won't adhere b/c system is not working
-don't want to give a pt who is not healing a second wound |
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what occurs as a result of the initial vasoconstriction?
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hypoxia
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what occurs as a result of hypoxia
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-angiogenisis
-release of NO2 -vasodilation |
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what is necessary for anti-bacterial actions in the cellular response
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Oxygen
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What is the charge of the skins surface
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negative
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4 main processes of the proliferative phase
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-angiogenesis
-granulation -contraction -re-epithelialization |
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what is required for angiogenesis?
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endothelial cells
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210.3
This is the process of gaining and maintaining discipline within your organization? It provides a way for the supervisor to establish lines of acceptability |
Progressive Discipline Process (PDP)
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what is the composition of of granulation tissue
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macrophages, fibroblasts, new vessels, immature collagen (type III), and EMC
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What is the purpose of granulation tissue
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-provides framework for cellular migration
-temporarily fills wound defect |
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what is one thing that effects the rate of closure
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the shape of the wound
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what is needed to induce CTGF
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TGF-Beta
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what are the main players in contraction
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myofibroblasts
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where does epithelialization occur?
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at the margins of the wound, across granulation tissue
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in what phase are keratinocytes key
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epithelialization
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what completes the proliferation phase?
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full epithelial coverage
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2 processes that occur during maturation
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synthesis and lysis
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which process during maturation does not require oxygen?
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lysis
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what is hypertrophic scarring
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excessive collagen synthesis which remains in the confines of wound margin
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what is a possible cause of a hypertrophic scar
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too much oxygen
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what is a keloid
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excessive collagen synthesis which progresses outside the confines of wound margin
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what is dehiscence
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separation of wound margins
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Why may PRP not be an effective Tx for chronic wounds
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person my have "defective" platelets which is why they have a chronic wound
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