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165 Cards in this Set

  • Front
  • Back
What are the ABC's of skin care
Asymmetry
Border
Color
Diameter
Give types of skin rashes
1. Dermatitis
2. Urticaria (Hives)
These can come from multiple causes including environmental exposure & stress--may be rxn to cold txt or tape

PTs dont really treat these much
Give the 3 types of elevated lesions
1. Flat
2. Elevated
3. Elevated/Fluid Filled
Describe a flat lesion
Macule or Patch---dark spot on the skin
Describe an Elevated lesion
Papule, Plaque, Nodule, Tumor, Wheal
Describe an Elevated Fluid Filled lesion
-Vesicle
-Bulla (Blister)
-Pustule (normally considered to be infected if filled with pus)
-Cyst
Describe some "Suspicious Lesions"
Bleeding mole because generally the outer part of the skin is avascular but with cancer the tumor is growing rapidly & needs increased blood supply to grow so angiogenisis occurs leading to easier bleeding

Angiogenesis is simply new vessel formation
Give 2 types of infected lesions
Abscess & Cellulitis

Often caused by Staph Aureus (microbe)
Describe types of Abscesses
1. Furuncle (boil)--Raised area of necrotic or purulent (Pusy) tissue
-Whitened area

2. Carbuncle--multiple interconnected furuncles occurring below the skin
Describe cellulitis
Caused by infection or inflammation

Normally red & swollen
What percent of body mass is skin
15-20%

0.5-0.6 mm thick
What are some types of secondary lesions.
1. Scales (epidermal)
2. Scabs (Crusts)
3. Abrasions (Excoriation)
4. Fissures (Linear in shape)
5. Erosions (Denuded) --outer layers of skin wearing away--smoother than abrasion
6. Ulcers
7. Scars
What ratio of resting cardiac output goes to skin
1/3

Lots of vascularization & blood supply to skin to keep it healthy so it takes increases cardiac output to get all this blood to the skin
What percent of body mass is skin
15-20%

0.5-0.6 mm thick
Give the 4 types of skin on the body
1. Mucocutaneous--at the junctions of the mucous membrane, hairy skin, lips, & tongue

2. Mucous Membrane--lining the inside of the body orifices--nose & mouth

3. Glaborous: skin without hair that tends to be thicker (palms and soles of feet)

4. Hairy--skin with hair
What is connective tissue made up of (3)
1. Matrix (collagen)
2. Fibers
3. Fibroblasts

The components and orientations of these 3 components differentiate each type of connective tissue
What ratio of resting cardiac output goes to skin
1/3

Lots of vascularization & blood supply to skin to keep it healthy so it takes increases cardiac output to get all this blood to the skin
What are some types of secondary lesions.
1. Scales (epidermal)
2. Scabs (Crusts)
3. Abrasions (Excoriation)
4. Fissures (Linear in shape)
5. Erosions (Denuded) --outer layers of skin wearing away--smoother than abrasion
6. Ulcers
7. Scars
What are some types of secondary lesions.
1. Scales (epidermal)
2. Scabs (Crusts)
3. Abrasions (Excoriation)
4. Fissures (Linear in shape)
5. Erosions (Denuded) --outer layers of skin wearing away--smoother than abrasion
6. Ulcers
7. Scars
What are some types of secondary lesions.
1. Scales (epidermal)
2. Scabs (Crusts)
3. Abrasions (Excoriation)
4. Fissures (Linear in shape)
5. Erosions (Denuded) --outer layers of skin wearing away--smoother than abrasion
6. Ulcers
7. Scars
What are some types of secondary lesions.
1. Scales (epidermal)
2. Scabs (Crusts)
3. Abrasions (Excoriation)
4. Fissures (Linear in shape)
5. Erosions (Denuded) --outer layers of skin wearing away--smoother than abrasion
6. Ulcers
7. Scars
What are some types of secondary lesions.
1. Scales (epidermal)
2. Scabs (Crusts)
3. Abrasions (Excoriation)
4. Fissures (Linear in shape)
5. Erosions (Denuded) --outer layers of skin wearing away--smoother than abrasion
6. Ulcers
7. Scars
Give the 4 types of skin on the body
1. Mucocutaneous--at the junctions of the mucous membrane, hairy skin, lips, & tongue

2. Mucous Membrane--lining the inside of the body orifices--nose & mouth

3. Glaborous: skin without hair that tends to be thicker (palms and soles of feet)

4. Hairy--skin with hair
What are some types of secondary lesions.
1. Scales (epidermal)
2. Scabs (Crusts)
3. Abrasions (Excoriation)
4. Fissures (Linear in shape)
5. Erosions (Denuded) --outer layers of skin wearing away--smoother than abrasion
6. Ulcers
7. Scars
What are some types of secondary lesions.
1. Scales (epidermal)
2. Scabs (Crusts)
3. Abrasions (Excoriation)
4. Fissures (Linear in shape)
5. Erosions (Denuded) --outer layers of skin wearing away--smoother than abrasion
6. Ulcers
7. Scars
Give the 3 types of connective tissue
1. Loose Connective Tissue (loosely packed fibers)

2. Regular CT--more dense (tendons and ligaments are made of this type)--formed with fibers organized in specific directions to stabilize from specific mvmt

3. Irregular CT--normally in skin, much looser
What are some types of secondary lesions.
1. Scales (epidermal)
2. Scabs (Crusts)
3. Abrasions (Excoriation)
4. Fissures (Linear in shape)
5. Erosions (Denuded) --outer layers of skin wearing away--smoother than abrasion
6. Ulcers
7. Scars
What percent of body mass is skin
15-20%

0.5-0.6 mm thick
What are the ABC's of skin care
Asymmetry
Border
Color
Diameter
What is connective tissue made up of (3)
1. Matrix (collagen)
2. Fibers
3. Fibroblasts

The components and orientations of these 3 components differentiate each type of connective tissue
Give the functions of skin as an organ
1. Serves as protection from the environment
-UV radiation
-Microbes
-Mechanical Stress

2. Immune FxN

3. Maintains Homeostasis

4. Provides Sensory feedback
-Mechanical and thermosensitive receptors

2.
What percent of body mass is skin
15-20%

0.5-0.6 mm thick
What percent of body mass is skin
15-20%

0.5-0.6 mm thick
Give types of skin rashes
1. Dermatitis
2. Urticaria (Hives)
These can come from multiple causes including environmental exposure & stress--may be rxn to cold txt or tape

PTs dont really treat these much
What percent of body mass is skin
15-20%

0.5-0.6 mm thick
What percent of body mass is skin
15-20%

0.5-0.6 mm thick
What percent of body mass is skin
15-20%

0.5-0.6 mm thick
What percent of body mass is skin
15-20%

0.5-0.6 mm thick
What percent of body mass is skin
15-20%

0.5-0.6 mm thick
What percent of body mass is skin
15-20%

0.5-0.6 mm thick
How does skin have an immune fxn
-Physical/Chemical Barrier

Has a low pH so very acidic for microbes

pH on the skin can be increased (more basic) with frequent hand washing--thus it may make one more prone to recieving germs as bacteriocidal effect of skin is decreased

pH is also affected by diabetes--which increases the risk of infection

Langerhans (Dendritic Cells)--important as Antigen Presenting Cells (APC's)
What percent of body mass is skin
15-20%

0.5-0.6 mm thick
What ratio of resting cardiac output goes to skin
1/3

Lots of vascularization & blood supply to skin to keep it healthy so it takes increases cardiac output to get all this blood to the skin
What ratio of resting cardiac output goes to skin
1/3

Lots of vascularization & blood supply to skin to keep it healthy so it takes increases cardiac output to get all this blood to the skin
What ratio of resting cardiac output goes to skin
1/3

Lots of vascularization & blood supply to skin to keep it healthy so it takes increases cardiac output to get all this blood to the skin
What ratio of resting cardiac output goes to skin
1/3

Lots of vascularization & blood supply to skin to keep it healthy so it takes increases cardiac output to get all this blood to the skin
What ratio of resting cardiac output goes to skin
1/3

Lots of vascularization & blood supply to skin to keep it healthy so it takes increases cardiac output to get all this blood to the skin
Give the 4 types of skin on the body
1. Mucocutaneous--at the junctions of the mucous membrane, hairy skin, lips, & tongue

2. Mucous Membrane--lining the inside of the body orifices--nose & mouth

3. Glaborous: skin without hair that tends to be thicker (palms and soles of feet)

4. Hairy--skin with hair
What ratio of resting cardiac output goes to skin
1/3

Lots of vascularization & blood supply to skin to keep it healthy so it takes increases cardiac output to get all this blood to the skin
What ratio of resting cardiac output goes to skin
1/3

Lots of vascularization & blood supply to skin to keep it healthy so it takes increases cardiac output to get all this blood to the skin
What ratio of resting cardiac output goes to skin
1/3

Lots of vascularization & blood supply to skin to keep it healthy so it takes increases cardiac output to get all this blood to the skin
What ratio of resting cardiac output goes to skin
1/3

Lots of vascularization & blood supply to skin to keep it healthy so it takes increases cardiac output to get all this blood to the skin
How does skin maintain homeostasis
1. Hydration Status
2. Thermoregulation
-Fat layer helps insulate; sweating & vasodilation cause convection of heat out of the air so blood can get shunted out of the skin to cool down

3. Helps maintain Vit D levels
-Important for bone & muscle health
Give the 3 types of elevated lesions
1. Flat
2. Elevated
3. Elevated/Fluid Filled
Give the 3 types of connective tissue
1. Loose Connective Tissue (loosely packed fibers)

2. Regular CT--more dense (tendons and ligaments are made of this type)--formed with fibers organized in specific directions to stabilize from specific mvmt

3. Irregular CT--normally in skin, much looser
Give the 4 types of skin on the body
1. Mucocutaneous--at the junctions of the mucous membrane, hairy skin, lips, & tongue

2. Mucous Membrane--lining the inside of the body orifices--nose & mouth

3. Glaborous: skin without hair that tends to be thicker (palms and soles of feet)

4. Hairy--skin with hair
What ratio of resting cardiac output goes to skin
1/3

Lots of vascularization & blood supply to skin to keep it healthy so it takes increases cardiac output to get all this blood to the skin
Give the 4 types of skin on the body
1. Mucocutaneous--at the junctions of the mucous membrane, hairy skin, lips, & tongue

2. Mucous Membrane--lining the inside of the body orifices--nose & mouth

3. Glaborous: skin without hair that tends to be thicker (palms and soles of feet)

4. Hairy--skin with hair
Give the 4 types of skin on the body
1. Mucocutaneous--at the junctions of the mucous membrane, hairy skin, lips, & tongue

2. Mucous Membrane--lining the inside of the body orifices--nose & mouth

3. Glaborous: skin without hair that tends to be thicker (palms and soles of feet)

4. Hairy--skin with hair
Describe the width of the dermis & epidermis
Epidermis: 0.06-0.6mm
Dermis: 2-4mm
Give the 4 types of skin on the body
1. Mucocutaneous--at the junctions of the mucous membrane, hairy skin, lips, & tongue

2. Mucous Membrane--lining the inside of the body orifices--nose & mouth

3. Glaborous: skin without hair that tends to be thicker (palms and soles of feet)

4. Hairy--skin with hair
Describe a flat lesion
Macule or Patch---dark spot on the skin
Give the 4 types of skin on the body
1. Mucocutaneous--at the junctions of the mucous membrane, hairy skin, lips, & tongue

2. Mucous Membrane--lining the inside of the body orifices--nose & mouth

3. Glaborous: skin without hair that tends to be thicker (palms and soles of feet)

4. Hairy--skin with hair
What is connective tissue made up of (3)
1. Matrix (collagen)
2. Fibers
3. Fibroblasts

The components and orientations of these 3 components differentiate each type of connective tissue
Give the 4 types of skin on the body
1. Mucocutaneous--at the junctions of the mucous membrane, hairy skin, lips, & tongue

2. Mucous Membrane--lining the inside of the body orifices--nose & mouth

3. Glaborous: skin without hair that tends to be thicker (palms and soles of feet)

4. Hairy--skin with hair
Give the 4 types of skin on the body
1. Mucocutaneous--at the junctions of the mucous membrane, hairy skin, lips, & tongue

2. Mucous Membrane--lining the inside of the body orifices--nose & mouth

3. Glaborous: skin without hair that tends to be thicker (palms and soles of feet)

4. Hairy--skin with hair
Give the 4 types of skin on the body
1. Mucocutaneous--at the junctions of the mucous membrane, hairy skin, lips, & tongue

2. Mucous Membrane--lining the inside of the body orifices--nose & mouth

3. Glaborous: skin without hair that tends to be thicker (palms and soles of feet)

4. Hairy--skin with hair
Give the 4 types of skin on the body
1. Mucocutaneous--at the junctions of the mucous membrane, hairy skin, lips, & tongue

2. Mucous Membrane--lining the inside of the body orifices--nose & mouth

3. Glaborous: skin without hair that tends to be thicker (palms and soles of feet)

4. Hairy--skin with hair
What is connective tissue made up of (3)
1. Matrix (collagen)
2. Fibers
3. Fibroblasts

The components and orientations of these 3 components differentiate each type of connective tissue
What is connective tissue made up of (3)
1. Matrix (collagen)
2. Fibers
3. Fibroblasts

The components and orientations of these 3 components differentiate each type of connective tissue
What is connective tissue made up of (3)
1. Matrix (collagen)
2. Fibers
3. Fibroblasts

The components and orientations of these 3 components differentiate each type of connective tissue
What is connective tissue made up of (3)
1. Matrix (collagen)
2. Fibers
3. Fibroblasts

The components and orientations of these 3 components differentiate each type of connective tissue
What is connective tissue made up of (3)
1. Matrix (collagen)
2. Fibers
3. Fibroblasts

The components and orientations of these 3 components differentiate each type of connective tissue
What is connective tissue made up of (3)
1. Matrix (collagen)
2. Fibers
3. Fibroblasts

The components and orientations of these 3 components differentiate each type of connective tissue
Give the functions of skin as an organ
1. Serves as protection from the environment
-UV radiation
-Microbes
-Mechanical Stress

2. Immune FxN

3. Maintains Homeostasis

4. Provides Sensory feedback
-Mechanical and thermosensitive receptors

2.
How does skin have an immune fxn
-Physical/Chemical Barrier

Has a low pH so very acidic for microbes

pH on the skin can be increased (more basic) with frequent hand washing--thus it may make one more prone to recieving germs as bacteriocidal effect of skin is decreased

pH is also affected by diabetes--which increases the risk of infection

Langerhans (Dendritic Cells)--important as Antigen Presenting Cells (APC's)
Give the 3 types of connective tissue
1. Loose Connective Tissue (loosely packed fibers)

2. Regular CT--more dense (tendons and ligaments are made of this type)--formed with fibers organized in specific directions to stabilize from specific mvmt

3. Irregular CT--normally in skin, much looser
What is connective tissue made up of (3)
1. Matrix (collagen)
2. Fibers
3. Fibroblasts

The components and orientations of these 3 components differentiate each type of connective tissue
Describe an Elevated lesion
Papule, Plaque, Nodule, Tumor, Wheal
Give the 3 types of connective tissue
1. Loose Connective Tissue (loosely packed fibers)

2. Regular CT--more dense (tendons and ligaments are made of this type)--formed with fibers organized in specific directions to stabilize from specific mvmt

3. Irregular CT--normally in skin, much looser
Give the 3 types of connective tissue
1. Loose Connective Tissue (loosely packed fibers)

2. Regular CT--more dense (tendons and ligaments are made of this type)--formed with fibers organized in specific directions to stabilize from specific mvmt

3. Irregular CT--normally in skin, much looser
Give the 3 types of connective tissue
1. Loose Connective Tissue (loosely packed fibers)

2. Regular CT--more dense (tendons and ligaments are made of this type)--formed with fibers organized in specific directions to stabilize from specific mvmt

3. Irregular CT--normally in skin, much looser
What is connective tissue made up of (3)
1. Matrix (collagen)
2. Fibers
3. Fibroblasts

The components and orientations of these 3 components differentiate each type of connective tissue
What is connective tissue made up of (3)
1. Matrix (collagen)
2. Fibers
3. Fibroblasts

The components and orientations of these 3 components differentiate each type of connective tissue
Give the 3 types of connective tissue
1. Loose Connective Tissue (loosely packed fibers)

2. Regular CT--more dense (tendons and ligaments are made of this type)--formed with fibers organized in specific directions to stabilize from specific mvmt

3. Irregular CT--normally in skin, much looser
Describe an Elevated Fluid Filled lesion
-Vesicle
-Bulla (Blister)
-Pustule (normally considered to be infected if filled with pus)
-Cyst
Give the 3 types of connective tissue
1. Loose Connective Tissue (loosely packed fibers)

2. Regular CT--more dense (tendons and ligaments are made of this type)--formed with fibers organized in specific directions to stabilize from specific mvmt

3. Irregular CT--normally in skin, much looser
Give the functions of skin as an organ
1. Serves as protection from the environment
-UV radiation
-Microbes
-Mechanical Stress

2. Immune FxN

3. Maintains Homeostasis

4. Provides Sensory feedback
-Mechanical and thermosensitive receptors

2.
Give the functions of skin as an organ
1. Serves as protection from the environment
-UV radiation
-Microbes
-Mechanical Stress

2. Immune FxN

3. Maintains Homeostasis

4. Provides Sensory feedback
-Mechanical and thermosensitive receptors

2.
Give the 3 types of connective tissue
1. Loose Connective Tissue (loosely packed fibers)

2. Regular CT--more dense (tendons and ligaments are made of this type)--formed with fibers organized in specific directions to stabilize from specific mvmt

3. Irregular CT--normally in skin, much looser
Give the functions of skin as an organ
1. Serves as protection from the environment
-UV radiation
-Microbes
-Mechanical Stress

2. Immune FxN

3. Maintains Homeostasis

4. Provides Sensory feedback
-Mechanical and thermosensitive receptors

2.
Give the 3 types of connective tissue
1. Loose Connective Tissue (loosely packed fibers)

2. Regular CT--more dense (tendons and ligaments are made of this type)--formed with fibers organized in specific directions to stabilize from specific mvmt

3. Irregular CT--normally in skin, much looser
Describe some "Suspicious Lesions"
Bleeding mole because generally the outer part of the skin is avascular but with cancer the tumor is growing rapidly & needs increased blood supply to grow so angiogenisis occurs leading to easier bleeding

Angiogenesis is simply new vessel formation
Give the functions of skin as an organ
1. Serves as protection from the environment
-UV radiation
-Microbes
-Mechanical Stress

2. Immune FxN

3. Maintains Homeostasis

4. Provides Sensory feedback
-Mechanical and thermosensitive receptors

2.
Give the functions of skin as an organ
1. Serves as protection from the environment
-UV radiation
-Microbes
-Mechanical Stress

2. Immune FxN

3. Maintains Homeostasis

4. Provides Sensory feedback
-Mechanical and thermosensitive receptors

2.
Give the 3 types of connective tissue
1. Loose Connective Tissue (loosely packed fibers)

2. Regular CT--more dense (tendons and ligaments are made of this type)--formed with fibers organized in specific directions to stabilize from specific mvmt

3. Irregular CT--normally in skin, much looser
Give the functions of skin as an organ
1. Serves as protection from the environment
-UV radiation
-Microbes
-Mechanical Stress

2. Immune FxN

3. Maintains Homeostasis

4. Provides Sensory feedback
-Mechanical and thermosensitive receptors

2.
How does skin have an immune fxn
-Physical/Chemical Barrier

Has a low pH so very acidic for microbes

pH on the skin can be increased (more basic) with frequent hand washing--thus it may make one more prone to recieving germs as bacteriocidal effect of skin is decreased

pH is also affected by diabetes--which increases the risk of infection

Langerhans (Dendritic Cells)--important as Antigen Presenting Cells (APC's)
Give the 3 types of connective tissue
1. Loose Connective Tissue (loosely packed fibers)

2. Regular CT--more dense (tendons and ligaments are made of this type)--formed with fibers organized in specific directions to stabilize from specific mvmt

3. Irregular CT--normally in skin, much looser
How does skin maintain homeostasis
1. Hydration Status
2. Thermoregulation
-Fat layer helps insulate; sweating & vasodilation cause convection of heat out of the air so blood can get shunted out of the skin to cool down

3. Helps maintain Vit D levels
-Important for bone & muscle health
How does skin have an immune fxn
-Physical/Chemical Barrier

Has a low pH so very acidic for microbes

pH on the skin can be increased (more basic) with frequent hand washing--thus it may make one more prone to recieving germs as bacteriocidal effect of skin is decreased

pH is also affected by diabetes--which increases the risk of infection

Langerhans (Dendritic Cells)--important as Antigen Presenting Cells (APC's)
Give the functions of skin as an organ
1. Serves as protection from the environment
-UV radiation
-Microbes
-Mechanical Stress

2. Immune FxN

3. Maintains Homeostasis

4. Provides Sensory feedback
-Mechanical and thermosensitive receptors

2.
How does skin maintain homeostasis
1. Hydration Status
2. Thermoregulation
-Fat layer helps insulate; sweating & vasodilation cause convection of heat out of the air so blood can get shunted out of the skin to cool down

3. Helps maintain Vit D levels
-Important for bone & muscle health
How does skin have an immune fxn
-Physical/Chemical Barrier

Has a low pH so very acidic for microbes

pH on the skin can be increased (more basic) with frequent hand washing--thus it may make one more prone to recieving germs as bacteriocidal effect of skin is decreased

pH is also affected by diabetes--which increases the risk of infection

Langerhans (Dendritic Cells)--important as Antigen Presenting Cells (APC's)
Give the functions of skin as an organ
1. Serves as protection from the environment
-UV radiation
-Microbes
-Mechanical Stress

2. Immune FxN

3. Maintains Homeostasis

4. Provides Sensory feedback
-Mechanical and thermosensitive receptors

2.
Give the functions of skin as an organ
1. Serves as protection from the environment
-UV radiation
-Microbes
-Mechanical Stress

2. Immune FxN

3. Maintains Homeostasis

4. Provides Sensory feedback
-Mechanical and thermosensitive receptors

2.
How does skin have an immune fxn
-Physical/Chemical Barrier

Has a low pH so very acidic for microbes

pH on the skin can be increased (more basic) with frequent hand washing--thus it may make one more prone to recieving germs as bacteriocidal effect of skin is decreased

pH is also affected by diabetes--which increases the risk of infection

Langerhans (Dendritic Cells)--important as Antigen Presenting Cells (APC's)
How does skin maintain homeostasis
1. Hydration Status
2. Thermoregulation
-Fat layer helps insulate; sweating & vasodilation cause convection of heat out of the air so blood can get shunted out of the skin to cool down

3. Helps maintain Vit D levels
-Important for bone & muscle health
Give the functions of skin as an organ
1. Serves as protection from the environment
-UV radiation
-Microbes
-Mechanical Stress

2. Immune FxN

3. Maintains Homeostasis

4. Provides Sensory feedback
-Mechanical and thermosensitive receptors

2.
How does skin have an immune fxn
-Physical/Chemical Barrier

Has a low pH so very acidic for microbes

pH on the skin can be increased (more basic) with frequent hand washing--thus it may make one more prone to recieving germs as bacteriocidal effect of skin is decreased

pH is also affected by diabetes--which increases the risk of infection

Langerhans (Dendritic Cells)--important as Antigen Presenting Cells (APC's)
How does skin have an immune fxn
-Physical/Chemical Barrier

Has a low pH so very acidic for microbes

pH on the skin can be increased (more basic) with frequent hand washing--thus it may make one more prone to recieving germs as bacteriocidal effect of skin is decreased

pH is also affected by diabetes--which increases the risk of infection

Langerhans (Dendritic Cells)--important as Antigen Presenting Cells (APC's)
Describe the width of the dermis & epidermis
Epidermis: 0.06-0.6mm
Dermis: 2-4mm
Give 2 types of infected lesions
Abscess & Cellulitis

Often caused by Staph Aureus (microbe)
How does skin maintain homeostasis
1. Hydration Status
2. Thermoregulation
-Fat layer helps insulate; sweating & vasodilation cause convection of heat out of the air so blood can get shunted out of the skin to cool down

3. Helps maintain Vit D levels
-Important for bone & muscle health
How does skin have an immune fxn
-Physical/Chemical Barrier

Has a low pH so very acidic for microbes

pH on the skin can be increased (more basic) with frequent hand washing--thus it may make one more prone to recieving germs as bacteriocidal effect of skin is decreased

pH is also affected by diabetes--which increases the risk of infection

Langerhans (Dendritic Cells)--important as Antigen Presenting Cells (APC's)
Describe the width of the dermis & epidermis
Epidermis: 0.06-0.6mm
Dermis: 2-4mm
How does skin have an immune fxn
-Physical/Chemical Barrier

Has a low pH so very acidic for microbes

pH on the skin can be increased (more basic) with frequent hand washing--thus it may make one more prone to recieving germs as bacteriocidal effect of skin is decreased

pH is also affected by diabetes--which increases the risk of infection

Langerhans (Dendritic Cells)--important as Antigen Presenting Cells (APC's)
How does skin maintain homeostasis
1. Hydration Status
2. Thermoregulation
-Fat layer helps insulate; sweating & vasodilation cause convection of heat out of the air so blood can get shunted out of the skin to cool down

3. Helps maintain Vit D levels
-Important for bone & muscle health
Describe the width of the dermis & epidermis
Epidermis: 0.06-0.6mm
Dermis: 2-4mm
How does skin have an immune fxn
-Physical/Chemical Barrier

Has a low pH so very acidic for microbes

pH on the skin can be increased (more basic) with frequent hand washing--thus it may make one more prone to recieving germs as bacteriocidal effect of skin is decreased

pH is also affected by diabetes--which increases the risk of infection

Langerhans (Dendritic Cells)--important as Antigen Presenting Cells (APC's)
How does skin have an immune fxn
-Physical/Chemical Barrier

Has a low pH so very acidic for microbes

pH on the skin can be increased (more basic) with frequent hand washing--thus it may make one more prone to recieving germs as bacteriocidal effect of skin is decreased

pH is also affected by diabetes--which increases the risk of infection

Langerhans (Dendritic Cells)--important as Antigen Presenting Cells (APC's)
How does skin maintain homeostasis
1. Hydration Status
2. Thermoregulation
-Fat layer helps insulate; sweating & vasodilation cause convection of heat out of the air so blood can get shunted out of the skin to cool down

3. Helps maintain Vit D levels
-Important for bone & muscle health
How does skin maintain homeostasis
1. Hydration Status
2. Thermoregulation
-Fat layer helps insulate; sweating & vasodilation cause convection of heat out of the air so blood can get shunted out of the skin to cool down

3. Helps maintain Vit D levels
-Important for bone & muscle health
Describe types of Abscesses
1. Furuncle (boil)--Raised area of necrotic or purulent (Pusy) tissue
-Whitened area

2. Carbuncle--multiple interconnected furuncles occurring below the skin
How does skin maintain homeostasis
1. Hydration Status
2. Thermoregulation
-Fat layer helps insulate; sweating & vasodilation cause convection of heat out of the air so blood can get shunted out of the skin to cool down

3. Helps maintain Vit D levels
-Important for bone & muscle health
Describe the width of the dermis & epidermis
Epidermis: 0.06-0.6mm
Dermis: 2-4mm
How does skin maintain homeostasis
1. Hydration Status
2. Thermoregulation
-Fat layer helps insulate; sweating & vasodilation cause convection of heat out of the air so blood can get shunted out of the skin to cool down

3. Helps maintain Vit D levels
-Important for bone & muscle health
How does skin maintain homeostasis
1. Hydration Status
2. Thermoregulation
-Fat layer helps insulate; sweating & vasodilation cause convection of heat out of the air so blood can get shunted out of the skin to cool down

3. Helps maintain Vit D levels
-Important for bone & muscle health
Describe the width of the dermis & epidermis
Epidermis: 0.06-0.6mm
Dermis: 2-4mm
Describe the width of the dermis & epidermis
Epidermis: 0.06-0.6mm
Dermis: 2-4mm
How does skin maintain homeostasis
1. Hydration Status
2. Thermoregulation
-Fat layer helps insulate; sweating & vasodilation cause convection of heat out of the air so blood can get shunted out of the skin to cool down

3. Helps maintain Vit D levels
-Important for bone & muscle health
Describe the width of the dermis & epidermis
Epidermis: 0.06-0.6mm
Dermis: 2-4mm
Describe the width of the dermis & epidermis
Epidermis: 0.06-0.6mm
Dermis: 2-4mm
Describe cellulitis
Caused by infection or inflammation

Normally red & swollen
Describe the width of the dermis & epidermis
Epidermis: 0.06-0.6mm
Dermis: 2-4mm
Describe the width of the dermis & epidermis
Epidermis: 0.06-0.6mm
Dermis: 2-4mm
Describe the width of the dermis & epidermis
Epidermis: 0.06-0.6mm
Dermis: 2-4mm
3 skin layers
Epidermis
Dermis
Subcutaneous (Hypodermis)
Describe Subcutaneous Tissue
Very variable in thickness--both within & across individuals

Dependent on adipose tissue
What is different about Glaborous skin
Only layer that has a stratum lucidum component

Tends to have thicker layers
Where are appendages such as nails, hair, & glands (sebaceuos & sweat) derived
Epidermis--anchored in the dermis
What are sebaceous glands fxn
Secrete oil--if they get backed up pimples form

Blackheads involve oil that has been sitting for a long time & has oxidized
Describe components of the Epidermis
-Epithelial Tissue

-Avascular
-Depends on diffusion of O2 & other nutrients from dermis

-Turnover occurs roughly on a monthly basis

-Provides a physical barrier (key region for Vitamin D synthesis)

Mostly comprised of Keratinocytes (made of Keratin)
Give the 4 layers of the Epidermis
1. Stratum Corneum--outer layer of dead cells--an excessive build up of dead cells forms a callus from increased pressure areas

2. Stratum Germanium

3. Stratum Spinosum

4. Stratum Basalum--basilar layer is where cells form & are keratinized

There is a 5th layer in glaborous skin called the stratum lucidium--occurs between the stratum cornem & germanium

3.
Give 3 other cell types found in the epidermis
1. Melanocytes--provide pigmentation & UV protection
-Contain melanin granules (deposited within the cytoplasm on side of cell closest to the light to protect from UV)
-Melanocytes are normally in basilar layer

2. Merkel Cells--Mechanoreceptors

3. Dendritic Cells--prominent in Stratum Spinosum
-Have immune fxn acting like APC's
Why may scars have discoloration
Extra melanin may be laid down during healing
What are the 2 layers of the dermis
1. Papillary Dermis
2. Reticular dermis
What is one major difference between the dermis and epidermis
Dermis is highly vascular--especially with lymphatic vessels
Describe the papillary dermis
Anchored to epidermis via basement membrane

Made of loose irregular connective tissue
Describe 3 cells found in the dermis
1. Fibroblasts
2. Macrophages
3. Mast Cells
-These secrete histamine--which helps us cause a rxn to things like poison ivy
How are the papillary loops helpful with the dermis' function
They increase the surface area of the vasculature in the dermis and increase the depth of penetration of vasculature into the epidermis from the dermis to improve diffusion of blood flow since the epidermis is avascular
What two types of glands are found in the dermis
1. Sebaceous--oils secreted to prevent drying
2. Sweat
What are 2 types of sweat glands
1. Eccrine (merocrine)
-All over skin--esp glaborous skin
-Thermoregulators
-Cholinergic innervation (via sympathetic system)

2. Apocrine
-Found in axilla & scalp
-Adrenergic
-Debatable fxn ---secrete pheromones

We have many more Eccrine sweat glands than Apocrine
Give 4 characteristics of the subcutaneous layer
1. Mostly adipose tisssue
-Provides energy stores
-Many fat soluble vitamins here

2. Fascia also in this region
-Made of dense connective tissue--can be regular or irregular

3. Contains larger blood vessels or lymphatics

4. Regional differences in thickness depending on things like bony prominences
What does labile mean
There is lots of turnover & dividing to reproduce in skin cells
What % of cancers are skin cancer
40%

Makes sense b/c cancers are very labile as cells continuing to tumor and metastisize out of control
Give 2 common types of skin cancer
1. Malignant Melanoma
-Involves changes in pigmentation
-Only 4% of cancers but 79% of deaths

2. Basal & Squamous Cell Carcinoma
-Much more common, but much higher cure rate--esp with early detection
Give 2 negative things that happen to skin with aging
1. Increased vulnerability to injury
2. Epidermal & dermal atrophu
List the negative changes that occur in skin with aging
1. Reduced cell turnover
2. Reduced vasculature
3. Reduced immune fxn
4. Reduced collagen quality
5. Reduced elastin
6. Diminished sensation
7. Impaired thermoregulation--explains why old ppl are always cold
8. Altered moisture maintenance
Difference in appearance b/t basal and squamos cells
Basal cells are more raised--squamous cells are flatter and may have darkened area
Melanoma appearance
Flat--blackened with poorly defined bordered and color changes
Furuncle appearance
Largely protruding from skin--look to be filled with fluid & usually have white-pusy area on outside