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45 Cards in this Set

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Anti-trematode (flukes)?
Praziquantel
Anti-nematode (roundworms)?
Mebendazole and Ivermectin
Inhibits microtbulue synthesis?
Mebendazole
Paralyze nematodes by increased GABA mediated neurotransmission?
Ivermectin
Ivermectin used to treat (2)?
Strongyloidies and Onchocerca (river blindness)
Causes elephantitis?
Treat with?
Wucheria bancrofti carried by female mosquito.
Treat with DEC [diethylcarbamazine].
Treat with DEC (3)?
Loa loa, toxocara canis, wuchereria bancrofti.
Food contaminated with eggs, caues granulomas (if in retina causes blindness) and visceral larva migrans.
Toxocara canis (treat with DEC)
Causes river blindness?
Onchocerca volvulus. Transmitted by female blackflies. Treat with Ivermectin.
Cestode means?
Trematode means?
Nematode means?
Tapeworm
Fluke
Roundworm
In drinking water, skin inflammation and ulceration
Dracunculus medinensis.
Treat with niridazole.
Transmitted by deer fly, causes swelling in skin. Can see worm crawling in conjunctiva.
Loa loa.
Treat with DEC.
Undercooked meat, usually pork, inflammation of muscle, periorbital edema.
Trichinella spiralis.
Treat with thiabendazole.
Diagnosis confirmed by demonstration of cysts on muscle biopsy.
Larvae in soil penetrate the skin. Intestinal infection. Pneumonitis and diarrhea malabsorption.
Strongyloides stercoralis.
Treat with Ivermectin/thiabendazole.
Causes anal pruritus. Migrates at night, fairly benign, seen with children.
Enterobius vermicularis (pinworm).
Treat with mebendazole.
Eggs visible in feces, intestinal infection.
Ascaris lumbricoides (giant roundworm).
Treat with mebendazole.
Larvae penetrate skin of feet, intestinal infection can cause anemia.
Can leed to poor growth in children.
Ancylostoma duodenale (hookworm). Treat with mebendazole.

Necator= hookworm.
Increase membrane permeability to Calcium leading to tetanic contraction and death.
Praziquantel.
Drugs used for PCP.
TMP-SMX, dapsone, pentamidine. Start prophylaxis when CD4 drops below 200 cells/mL in HIV patients.
Undercooked crab meat. Inflammation and secondary bacterial infection of lung.
Paragonimus westermani. Treat with Praziquantel.
Also have hemoptysis.
Undercooked fish, inflammation of the biliary tract.
Clonorchis sinensis. Treat with Praziquantel.
Water snails are intermediate host. Granulomas, fibrosis, and inflammation of spleen and liver.
Schistosoma (blood fluke).
Treat with Praziquantel.
Undercooked pork tapeworm. Larvae cause mass lesions in the brain, cysticercosis.
Taenia solium.
Praziquantel.
Albendazole for cysticercosis.
Eggs in dog feces when ingested can cause cysts in liver.
Echinococcus granulosus.
Treat with albednazole.
Can cause anaphylaxis if echinococcal antigens released from cysts (as seen on "House"!).
Treat with Metronidazole (3)?
GET on the Metro.
Giardia, Entamoeba, and Trichomonas vaginalis.
Nifurtimox used to treat?
Chagas disease caused by Trypanosoma cruzi (converts drug to toxic free radicals).
Suramin used to treat?
African sleeping sickness (T. brucei,gambiense, rhodesiense) transmitted by Tsetse fly. Used before CNS involvement.
Melarsoprol used to treat?
Sleeping sickness with CNS involvement because drug readily enters CNS.
Very toxic, use only justified in life threatening infections.
Sodium stibogluconate used to treat?
Treatment of cutaneous, mucocutaneous, and visceral (Kala-Azar) leishmaniasis. Transmitted by sandfly.
Diseases transmitted by Ixodse tick?
Babesia (treat quinine/clindamycin) and Borrelia burgdorferi (treat tetracycline).
Bloating, flatulence, foul smelling diarrhea.
Giardia. Pear shape, owl's eye appearance.
Severe diarrhea in AIDS?
Cryptosporidium. No treatment.
Brain abscess in HIV?
Toxoplasma. Treat with sulfadiazine+pyrimethamine (similar to TMP).
Prevent relapse caused by P. vivax and P. ovale?
Primaquine.
Tissue schizonticide. Eradicates liver stages of these organisms.
Blood schizonticide?
Chloroquine.
Drugs contraindicated in patients with G6PD deficiency?
Sulfas (TMP-SMX), dapsone, primaquine, quinine, nitrofurantoin.
Strawberry colored mucosa? Foul smelling, greenish discharge.
Trichomonas vaginalis. Sexual transmission.
B12 deficiency
Diphyllobothrium latum
Fish tapeworm found in Scandanavia and the Great Lakes.
Portal hypertension.
Schistosoma mansoni
Hematuria, bladder cancer
Schistosoma haematobium
Microcytic anemia
Ancylostoma, necator.
Antibiotics to avoid during pregnancy?
SAFE Moms Take Really Good Care:

Sulfonamides, Aminoglycosides, Fluoroquinolones, Erythromycin, Metronidazole, Tetracyclines, Ribavirin, Griseofulvin, Chloramphenicol.
Flucytosine?
Used in systemic fungal infections.
Inhibits DNA synthesis by conversion to fluorouracil.
Used for invasive aspergillosis
Caspofungin which inhibits cell wall synthesis.
May enhance warfarin metabolism, interferes with microtubules function, disrupts mitosis.
Griseofulvin.
Oral treatment of superficial infections, inhibits growth of dermatophytes.