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45 Cards in this Set
- Front
- Back
Anti-trematode (flukes)?
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Praziquantel
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Anti-nematode (roundworms)?
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Mebendazole and Ivermectin
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Inhibits microtbulue synthesis?
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Mebendazole
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Paralyze nematodes by increased GABA mediated neurotransmission?
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Ivermectin
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Ivermectin used to treat (2)?
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Strongyloidies and Onchocerca (river blindness)
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Causes elephantitis?
Treat with? |
Wucheria bancrofti carried by female mosquito.
Treat with DEC [diethylcarbamazine]. |
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Treat with DEC (3)?
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Loa loa, toxocara canis, wuchereria bancrofti.
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Food contaminated with eggs, caues granulomas (if in retina causes blindness) and visceral larva migrans.
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Toxocara canis (treat with DEC)
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Causes river blindness?
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Onchocerca volvulus. Transmitted by female blackflies. Treat with Ivermectin.
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Cestode means?
Trematode means? Nematode means? |
Tapeworm
Fluke Roundworm |
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In drinking water, skin inflammation and ulceration
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Dracunculus medinensis.
Treat with niridazole. |
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Transmitted by deer fly, causes swelling in skin. Can see worm crawling in conjunctiva.
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Loa loa.
Treat with DEC. |
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Undercooked meat, usually pork, inflammation of muscle, periorbital edema.
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Trichinella spiralis.
Treat with thiabendazole. Diagnosis confirmed by demonstration of cysts on muscle biopsy. |
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Larvae in soil penetrate the skin. Intestinal infection. Pneumonitis and diarrhea malabsorption.
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Strongyloides stercoralis.
Treat with Ivermectin/thiabendazole. |
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Causes anal pruritus. Migrates at night, fairly benign, seen with children.
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Enterobius vermicularis (pinworm).
Treat with mebendazole. |
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Eggs visible in feces, intestinal infection.
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Ascaris lumbricoides (giant roundworm).
Treat with mebendazole. |
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Larvae penetrate skin of feet, intestinal infection can cause anemia.
Can leed to poor growth in children. |
Ancylostoma duodenale (hookworm). Treat with mebendazole.
Necator= hookworm. |
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Increase membrane permeability to Calcium leading to tetanic contraction and death.
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Praziquantel.
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Drugs used for PCP.
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TMP-SMX, dapsone, pentamidine. Start prophylaxis when CD4 drops below 200 cells/mL in HIV patients.
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Undercooked crab meat. Inflammation and secondary bacterial infection of lung.
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Paragonimus westermani. Treat with Praziquantel.
Also have hemoptysis. |
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Undercooked fish, inflammation of the biliary tract.
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Clonorchis sinensis. Treat with Praziquantel.
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Water snails are intermediate host. Granulomas, fibrosis, and inflammation of spleen and liver.
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Schistosoma (blood fluke).
Treat with Praziquantel. |
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Undercooked pork tapeworm. Larvae cause mass lesions in the brain, cysticercosis.
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Taenia solium.
Praziquantel. Albendazole for cysticercosis. |
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Eggs in dog feces when ingested can cause cysts in liver.
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Echinococcus granulosus.
Treat with albednazole. Can cause anaphylaxis if echinococcal antigens released from cysts (as seen on "House"!). |
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Treat with Metronidazole (3)?
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GET on the Metro.
Giardia, Entamoeba, and Trichomonas vaginalis. |
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Nifurtimox used to treat?
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Chagas disease caused by Trypanosoma cruzi (converts drug to toxic free radicals).
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Suramin used to treat?
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African sleeping sickness (T. brucei,gambiense, rhodesiense) transmitted by Tsetse fly. Used before CNS involvement.
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Melarsoprol used to treat?
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Sleeping sickness with CNS involvement because drug readily enters CNS.
Very toxic, use only justified in life threatening infections. |
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Sodium stibogluconate used to treat?
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Treatment of cutaneous, mucocutaneous, and visceral (Kala-Azar) leishmaniasis. Transmitted by sandfly.
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Diseases transmitted by Ixodse tick?
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Babesia (treat quinine/clindamycin) and Borrelia burgdorferi (treat tetracycline).
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Bloating, flatulence, foul smelling diarrhea.
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Giardia. Pear shape, owl's eye appearance.
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Severe diarrhea in AIDS?
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Cryptosporidium. No treatment.
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Brain abscess in HIV?
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Toxoplasma. Treat with sulfadiazine+pyrimethamine (similar to TMP).
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Prevent relapse caused by P. vivax and P. ovale?
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Primaquine.
Tissue schizonticide. Eradicates liver stages of these organisms. |
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Blood schizonticide?
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Chloroquine.
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Drugs contraindicated in patients with G6PD deficiency?
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Sulfas (TMP-SMX), dapsone, primaquine, quinine, nitrofurantoin.
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Strawberry colored mucosa? Foul smelling, greenish discharge.
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Trichomonas vaginalis. Sexual transmission.
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B12 deficiency
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Diphyllobothrium latum
Fish tapeworm found in Scandanavia and the Great Lakes. |
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Portal hypertension.
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Schistosoma mansoni
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Hematuria, bladder cancer
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Schistosoma haematobium
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Microcytic anemia
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Ancylostoma, necator.
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Antibiotics to avoid during pregnancy?
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SAFE Moms Take Really Good Care:
Sulfonamides, Aminoglycosides, Fluoroquinolones, Erythromycin, Metronidazole, Tetracyclines, Ribavirin, Griseofulvin, Chloramphenicol. |
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Flucytosine?
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Used in systemic fungal infections.
Inhibits DNA synthesis by conversion to fluorouracil. |
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Used for invasive aspergillosis
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Caspofungin which inhibits cell wall synthesis.
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May enhance warfarin metabolism, interferes with microtubules function, disrupts mitosis.
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Griseofulvin.
Oral treatment of superficial infections, inhibits growth of dermatophytes. |