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30 Cards in this Set
- Front
- Back
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Prazosin
class of drug and mode of action? |
selective alpha blocker
relaxation of smooth muscles (inhibits vasoconstriction) |
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Simvastatin
class of drug and mode of action? |
HMG-CoA reductase inhibitor
inhibits cholesterol synthesis |
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Warfarin
class of drug and mode of action? |
anti-cagulant (vitamin K antagonist)
Inhibits synthesis of Vk dependent clotting factors (II VII IX X) |
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In dental chair what precautions to take when pt has cardiac probs?
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Don't place head lower below heart level
Raise legs slightly If unconscious: tilt the chair back to horizontal Place pt in recovery position Cold towel on forehead |
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Classes of drugs that can cause orthostatic syncope?
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Beta blockers
Diuretic Selective alpha blocker Hypolipidemic drugs Anticoagulant |
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Why avoid grapefruit when taking simvastatin?
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increase the level of simvastatin in blood and increase chances of side effects
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Examples of beta blockers?
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metoprolol
propranolol |
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examples of diuretics?
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hydrochlorothiazide
amiloride frusemide |
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What's hydrochlorothiazide?
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diuretic
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What's amiloride?
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diuretic
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what's frusemide?
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diuretic
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Name anticoagulants other than warfarin
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aspirin
heparin clopidogrel |
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What is tranexamic acid? how does it work?
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anti-fibrolytics (inhibits clot breakdown)
Inhibits activation of plasminogen to plasmin |
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What's nitrate spray used for?
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treatment of angina
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What's contained in nitrate spray?
Mode of action? |
glyceryl trinitrate
provides exogenous source of nitric oxide (vasodilator) |
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Hos is nitrate spray admined?
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one metered dose under the tongue
if pain persists after 5min admin 2nd dose |
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Active ingredient of viagra?
mode of action? |
sildenafil
breakdown of cGMP >> results in smooth muslce relaxation >> increased blood into corpus cavernosum |
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Consequence of having viagra and nitrate spray together?
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extensive relaxation of smooth muscles:
decrease in BP orthostatic syncope |
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How is GTN tablet are admined?
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sublingually
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How can u know if GTN is active?
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it fizzes if active when admined
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How must GTN be stored?
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in original glass bottle
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Example of Calcium channel blocker?
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Nifepidine
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Drugs that cause gingival hyperplasia?
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nifepidine
cyclosporin phenytoin |
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What is ACE inhibitor?
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angiotensin-converting enzyme inhibitors are a group of drugs used primarily for the treatment of hypertension
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What is Captopril?
ADR? |
ACE inhibitor for treating hypertension
ADR: potassium retention (hyperkalaemia) |
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What's Digoxin?
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A medication for treating heart conditions
(Increases force of myocardial contraction and decreases atrioventricular (AV) nodal conduction) |
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What's a common ADR of ACE inhibitor?
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chronic cough
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What is Hydrochlorothiazide and what's its ADR?
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Diuretic drug which acts by inhibiting the kidneys' ability to retain water.
ADR: excretion of potassium |
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What drugs cause triple whammy and what is the consequence?
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Diuretics, ACE inhibitors and NSAIDs
renal failure |
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What analgesics are safe for a pt who's on ACE inhibior and diuretics?
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opiods and paracetamol
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