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20 Cards in this Set

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Paromomycin & Iodoquinol are _______ Amebicides
luminal
This is an antimalarial drug that is also a systemic amebicidal
Chloroquine
this drug acts in the food vacuole of the parasite to inhibit the metabolism of heme which is highly toxic to the parasite
Chloroquine
cloroquin toxicities
Ototoxicity, retinopathy
this mixed systemic luminal antiprotazoal is reduced to a highly reactive free radical which denatures DNA in the pathogen
Metronidazole
Selective vs anaerobic organisms e.g. Trichomoniasis vaginalis,E. histolytica & G. Lambli.
Metronidazole
Side effects of metronidazole
Disulfuram-Like Reaction with alcohol vasodilation, severe headache, profuse sweating
DOC for Giardiasis & Trichomoniasis
Metronidazole
alternative to Metronidazole
Tinadazole
Effective for toxoplasmic encephalitis in AIDS
Pyrimethamine + Sulfadiazine
Pyrimethamine + Sulfadiazine MOA
inhibit two sequential steps in synthesis of folic acid required for DNA synthesis
Used to treat roundworms, esp. pinworms
Mebendazole
this drug for pinworms and roundworms is a depolarizing neuromuscular blocker
Pyrantel
Ivermectin is a DOC for the
threadworm
can cause the Mazotti Reaction: fever, dizziness, rash, D, weakness, pruritis, joint & muscle pain, hypotension, tachycardia & edema.
Ivermectin
________ is the Rx of choice for blood flukes
Praziquantel
Indicated for pork tapeworms and cestodal infx., e.g. neurocysticercosis , hydatid disease.
Albendazole
this antimalarial drug can cause cinconism and hyperinsulinemia
Quinine
This antimalarial medication can exacerbate epilepsy & psychiatric disorders → convulsions, anxiety, paranoid, depression. Suicide Warning
Mefloquine
Primaquine can cause this in pts w/ ↓G6PD
Methemoglobinemia → cyanosis