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20 Cards in this Set
- Front
- Back
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Paromomycin & Iodoquinol are _______ Amebicides
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luminal
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This is an antimalarial drug that is also a systemic amebicidal
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Chloroquine
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this drug acts in the food vacuole of the parasite to inhibit the metabolism of heme which is highly toxic to the parasite
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Chloroquine
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cloroquin toxicities
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Ototoxicity, retinopathy
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this mixed systemic luminal antiprotazoal is reduced to a highly reactive free radical which denatures DNA in the pathogen
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Metronidazole
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Selective vs anaerobic organisms e.g. Trichomoniasis vaginalis,E. histolytica & G. Lambli.
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Metronidazole
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Side effects of metronidazole
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Disulfuram-Like Reaction with alcohol vasodilation, severe headache, profuse sweating
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DOC for Giardiasis & Trichomoniasis
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Metronidazole
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alternative to Metronidazole
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Tinadazole
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Effective for toxoplasmic encephalitis in AIDS
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Pyrimethamine + Sulfadiazine
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Pyrimethamine + Sulfadiazine MOA
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inhibit two sequential steps in synthesis of folic acid required for DNA synthesis
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Used to treat roundworms, esp. pinworms
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Mebendazole
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this drug for pinworms and roundworms is a depolarizing neuromuscular blocker
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Pyrantel
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Ivermectin is a DOC for the
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threadworm
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can cause the Mazotti Reaction: fever, dizziness, rash, D, weakness, pruritis, joint & muscle pain, hypotension, tachycardia & edema.
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Ivermectin
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________ is the Rx of choice for blood flukes
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Praziquantel
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Indicated for pork tapeworms and cestodal infx., e.g. neurocysticercosis , hydatid disease.
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Albendazole
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this antimalarial drug can cause cinconism and hyperinsulinemia
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Quinine
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This antimalarial medication can exacerbate epilepsy & psychiatric disorders → convulsions, anxiety, paranoid, depression. Suicide Warning
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Mefloquine
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Primaquine can cause this in pts w/ ↓G6PD
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Methemoglobinemia → cyanosis
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