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14 Cards in this Set
- Front
- Back
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pathophys
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hypothalmus...GnRH
ant. pit... FSH and LH endometrium responds -estrogen = proliferation -pogesteron = secretory |
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what does estrogen do
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secondary sex characteristics
bone growth/maintenance clotting metabolism |
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exogenous extrogens
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conjugated & estradiol
HRT menopausal symptoms bone density CV health (doesnt prevent hrt disease tho) CI: breast CA, DVT, liver disease |
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progesterone
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from corpus luteum
maintains pregnancy PMS relaxes smooth muscle |
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uses for estrogens and progesterones
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DUB (dysfcn'l uterine bleed)
amenorrhea endometriosis endometrial CA PMS (Reacts w/ SSRIs, benzos); calcium PMDD |
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benefits of HRT
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prevent osteoporosis
-dec fractures dec. colon CA dec. vasomotor symptoms (menopausal) inc. urogenital integrity |
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risks of HRT
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MI, stroke, dementia, DVT, CA, PE
do the benefits outweigh the risks? |
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SERM
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selective estrogen receptor modulator
(raloxifene) blocks receptors decreases risk of CA CI: h/o venous thrombosis |
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biphophonates
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(foxamax, actonel)
prevent/Tx osteoporosis and Paget's *empty stomach w/ glass of water upon waking *stay upright @ least 1/2 hr *need vit D and calcium suppl. |
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oral contraceptives
adverse effects and CI |
AE: DVT, HTN, CA, teratogenic
CI: pregnant, h/o thrombosis Drug Ix: rifampin, ritovir, dilantin, phenobarbs, st. johns wart, ampicillin, tetracycline |
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Missed OC pills
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1 - take w/ next scheduled dose
2 - 2 doses next 2 days 3 - new cycle start |
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post coital contraception
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RU486 (rape victims): ctx of uterus; spont abor, 72 hrs
methotrexate: abortion and ectopics prostaglandins: cervical ripening **report extreme cramping/bleeding/pain |
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tocolytics
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delay premature birth
Mag sulfate -watch levels -renal fcn -DTRs B2-agonists SQ, IV (terbutaline) -also for asthma relaxes uterus -makes you tachycardic |
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oxytotics
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induce labor
crtl post-part bleeding **make sure cervix is ripended first -IV pump -monitor ctx/bleeding |
