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159 Cards in this Set
- Front
- Back
Menarche begins at what time in life?
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12-13 years
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What is perimenopause?
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Regression in ovarian function
Has a loss of estrogen, hot flashes, emotional changes, and wt gain Cyclical symptoms every 20-30min |
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What is menopause?
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cessation of menses
concerns with: loneliness, depression, and financial stress |
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Chance of breast cancer in women
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1 in 7 women
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*Signs of Breast Cancer
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*lump
*pain in breast *discharge *skin changes |
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Breast Cancer Screening
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BSE Q1mo starting at age 20
Clinical Exam: 20-40 Q3yrs >35 yearly if at risk >40 yearly Mammogram >39 Q 1yr |
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Cervical CA is most often related to _________
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sexual history-HPV
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What is the most common kind of gynecological CA?
greatest risk? sign? |
Uterine
often the greatest risk is age vaginal bleeding esp post menopausal |
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Most fatal gynecological CA is what?
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Ovarian
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What is the leading cause of death in women?
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CVD
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Woman's chance of dying from CVD
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1 in 3 women
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*S&S of MI in women
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*unspecified pain
vague symptoms back pain fatigue SOB and weakness diabetes |
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Risk factors of osteoporosis
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smoking, alcohol, small thin frame, soft drinks and coffee, inactivity, low Ca, Hysterectomy b4 50
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Cycles of Abuse: Sunshine
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shower with kindness, bonding intensified, begs for forgiveness
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Cycles of Abuse: Clouds
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Tension build, batterer becomes possessive, woman accepts responsibility, isolation and threats, arguments
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Cycles of Abuse: Storm
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Acute battering, shock and denial after attack, rationalization of abuse
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Estrogen
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controls 2ndary sex characteristics
assists in maturing ovarian follicle proliferates endometrial mucus |
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Progesterone
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effects and cotnrols uterine endometrium to prepare for implantation
Related to temp at ovulation |
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PGE
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vasodilator
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PGF
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vasoconstrictor
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GnRH
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signals anterior pituitary to secrete FSH and LH
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FSH
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matures ovarian follicle and influences estrogen
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LH
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final maturation of follicle
*peak prod causes ovulation |
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What are the two ovarian cycle phases?
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The follicular phase and the luteal phase
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What happens during the follicular phase?
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immature follicles mature as a result of FSH
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What occurs during the luteal phase?
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Ovum leaves the follicle
Corpus luteum develops from the ruptured follicle(will degenerate if not fertilized) |
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What is the average blood loss during the menstrual cycle? and Iron loss?
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30mL
0.5 to 1mg daily |
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What are the four phases of the menstrual cycle?
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Menstrual phase
Proliferative phase Secretory phase Ischemic phase |
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What hormones are the ovaries sensitize to?
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FSH and LH
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What hormones are the uterus and breast sensitive to?
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Estrogen and progesterone
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What hormones change to maintain pregnancy after the ovum has been fertilized?
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Estrogen and progesterone
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What is the fertility period for ova and sperm?
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Ova- 12-24 hours
Sperm- 24 hours most fertile up to 72hrs |
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What is the acrosomal reaction?
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When millions of sperm surround the ovum, releasing enzymes to breakdown the outer layer of the ovum's shell
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What is the reaction that prevents additional sperm from entering the single ovum?
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Cortical reaction
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Different in zygotes between fraternal and identical twins
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Fraternal- dizygotic
Identical- monozygotic |
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Implantation occurs when?
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7-10 days after fertilization
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What hormone causes thickening of the endometrium after implantation changing the endomentrium to the decidua?
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Progesterone
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The embryonic membranes are called what?
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The amnion and chorion
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What is the function of the placenta?
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metabolic and nutrient exchange between mother and embryo
Secretes estradiol to maintain pregnancy |
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*Umbilical Cord
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*Two arteries and one vein- AVA
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*Wharton's Jelly
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*CT that surrounds vessels of umbilical cord and prevents compression
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*Umbilical Vein
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*carries O2 to the fetus
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*2 umbilical arteries
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*carries deoxygenated blood to the placenta
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What are the three stages of human development?
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Preembryonic stage
Embryonic stage Fetal stage |
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Preembryonic Stage
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first 14 days of human development
Establishes the endoderm, mesoderm, and ectoderm |
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Embryonic Stage
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15 days after conception to 8 weeks
Extreme vulnerability to teratogens |
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Fetal Stage
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8 weeks until birth
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What is the major cause of mental retardation in the US
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Fetal Alcohol Syndrome
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Marijuana's effect on pregnancy
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no teratogenic effects
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What is toxoplasmosis?
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from toxoplasma gondii
contracted by eating raw or poorly cooked meat, drinking unpasteurized goat's milk,or contact with infected cat feces |
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Rubella
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can be contracted by MMR vaccine
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CMV
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is asymptomatic in women so can be transmitted to fetus unbeknown to woman
NO TREATMENT |
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HSV
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from herpes
meds can help decrease viral shredding but has NO TREATMENT |
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Purpose of braxton-hicks contractions
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stimulate blood flow through the intervillous spaces of the placenta
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What hormone maintains the corpus luteum during early pregnancy?
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hCG
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Amount of air increase during pregnancy
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30-40%
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Blood volume increase during pregnancy
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40-45%
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Vital sign changes during pregnancy
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Pulse increase 10-15bpm
BP decreases slightly |
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Supine Hypotension/Vena Caval Syndrome/Aortocaval Compression
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uterus puts pressure on vena cava when woman is supine resulting in decreased BP
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Avg WBC count during pregnancy
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5000-12000
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Normal Wt gain overall
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norm wt- 25-35 lbs
overwt- 15-25 lbs underwt- ideal + 25-35 lbs |
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Wt gain by trimester
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3.5-5
12-15 12-15 |
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What hormone is responsible for initial lactation
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Prolactin
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Oxytocin
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affects uterine contractility and milk ejection from breasts
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*hCG
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*stimulates progesterone and estrogen production by the Corpus Luteum until placenta takes over
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hPL
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acts against insulin so that maternal metabolism of glucose to favor fetal growth
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*Estrogen
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*stimulates uterine development
develops ductal system of breasts to prepare for lactation |
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*Progesterone
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*MOST CRUCIAL HORMONE IN MAINTAINING PREGNANCY
*Maintains endometrium *inhibits spontaneous uterine contractility *develops breasts for lactation |
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*Relaxin
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*Inhibits uterine contractility
*diminishes strength of uterine contractions |
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*signs of pregnancy: Subjective/Presumptive
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*amenorrhea
N&V *excessive fatigue *urinary frequency *breast tenderness |
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*signs of pregnancy: Objective/Probably
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*changes in pelvic organs
*goodell's sign(softening of cervix) *Chadwick's sign(blue coloration of cervix) *Hegars sign: softening of isthmus of cervix *McDonalds signs: easing of flexing of body of uterus against the cervix |
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Goodell's sign
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softening of the cervix
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Chadwick's sign
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deep red to purple/blue coloration of cervix, mucus membranes, and vagina
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Hegar's Sign
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Softening of the isthmus of the cervix
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McDonalds sign
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easing of flexing of body of uterus against cervix
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Ballotment test
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touches cervix, something moves off and comes back
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Prime example of objective sign of pregnancy
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Pregnancy tests(measures hCG)
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Positive signs of pregnancy
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FHB, Fetal mvmnt, visualization of fetus by ultrasound
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definition of gestation
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number of weeks since the 1st day of LMP
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Definition of abortion
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birth that occurs befre the endof 20 weeks gestation
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Normal "Term" of pregnancy
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38-42 weeks
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Definition of preterm/premature birth
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After 20 weeks and before 37
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Definition of Gravida
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Any pregnancy, regardless of duration, including present pregnancy
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Nulligravida
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woman who has never been pregnant
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Primigravida
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Woman pregnant for the first time
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Multigravida
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Woman in her second or subsequent pregnancy
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Definition of Para
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birth after 20 weeks, regardless of outcome
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Nullipara
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Woman who has not given birth at more than 20 weeks EGA
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Stillbirth
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Fetus born dead after 20 weeks gestation
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Nagele's Rule
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1st day of LMP-3months+7days
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Fundal Ht
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corresponds in cm measurement between 22-34 weeks
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What is quickening?
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fetal movements felt by mother-occurs around 20 weeks
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FHB detected when?
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10-12 weeks w/ doppler
16-20 w/ fetoscope |
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Fetal heart activity seen when?
Fetal breathing movement seen when? |
6-7weeks
10-11weeks |
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Discomforts of Pregnancy: N&V
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due to increased hCG, gastric overload, slowed peristalsis
usually resolves by 16th week |
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Discomforts of Pregnancy: Urinary Frequency(patient teaching)
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maintain adequate fluid intake!
void q2hrs wheen awake Kegel exercises help |
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Discomforts of Pregnancy: Fatigue
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Not as bad 2nd trimester and bad again the 3rd
due to change in metabolic rate |
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Discomforts of Pregnancy: Nasal stuffiness
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due to estrogen engorged mucus membranes
teach cool air vaporizers/saline spray |
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Discomforts of Pregnancy: Heartburn
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Due to increased progesterone causing relaxation of sphincter to esophagus, GI motility, increased uterine size
worse in 2nd and 3rd trimesters |
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Discomforts of Pregnancy: Dependent Edema
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uterus causes impaired venous return
teach avoidance of constricting clothing, elevate legs and feet every 2-3hours lie on side instead of back |
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Discomforts of Pregnancy: Hemorrhoids
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Due to constipation, pressure of the uterus on the bowel, relaxing effects of progesterone
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Discomforts of Pregnancy: Constipation
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due to decreased peristalsis from progesterone, displacement and compression of bowel
can be side effect of Fe tabs |
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Upper backache can be treated w/ what?
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good support bra. pain is from enlarged breasts
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Discomforts of Pregnancy: Leg Cramps
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due to enlarged uterus
treat w/ straightening legs and exercise +elevation calcium phosphorous |
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Discomforts of Pregnancy: SOB
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uterus puts pressure on diaphragm
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Discomforts of Pregnancy: Round Ligament Pain
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Tx: flex knees into abdomen, warm baths, heating paid, support uterus w/ pillow, change positions
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Classifications of Anemia
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levels of Hgb <12 in nonpregnant and <11 in pregnant client
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What is the most common medical complication of pregnancy?
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Iron deficiency anemia
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Prevention/Tx of IDA
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27mg/day to prevent, 60-120mg/day if diagnosed
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Common SE of Iron supplements
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tarry stools
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Prevention/Tx of Folic Acid Deficiency Anemia
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.4mg folate
1mg folate |
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Sickle Cell Anemia
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Normal adult hGB and abnormal HbA
RBCs become crescent shaped clog capillaries esp in spleen, bone marrow,and placenta |
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Sickle Cell Anemia can cause what in Maternal client?
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high temp, dehydration, infection, acidosis, low o2 pressure, vaso-occlusive crisis
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Vaso-occlusive crisis
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Sudden attacks of pain secondary to ischemia from occluded capillaries
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Fetal/Neonatal risk of Sickle Cell Anemia
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Prematurity and IUGR, perinatal mortality
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Sickle Cell Anemia Tx
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folic acid supplements, prevent dehydration, administer o2, analgesics and antibiotics
Monitor fetal HR!!!!! |
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*Fetal risks with Maternal HIV
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transmission 15-25% W/out medicine
<2% if treated with zidovudine and delivered via C/S |
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*Fetal risks for infant AIDS
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encephalopathy characterized by delayed developmental milestones or loss of skills
found in 50-90% of children w/ AIDS |
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Heart disease classifications
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Class I-IV- from uncompromised to severely compromised
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Clinical signs of ectopic pregnancy
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one sided lower abdominal pain
vasomotor disturbances referred rt shoulder pain adnexcal tenderness bleedling abdomen rigid and tender lower hCG levels |
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*Abruptio Placenta
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premature separation of a normally implanted placenta from the uterine wall
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*Gestational Diabetes screening
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1 hour glucose tolerance test @24-28 weeks
if 130-140 or above, 3 hour diagnostic test is ordered |
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PROM
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spontaneous rupture of membranes prior to the onset of labor <37 weeks
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Tests to determine PROM
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fern test, ultrasound, nitrazine paper,
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Number one cause of neonatal mortality in the US
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prematurity
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Risk factors for preterm labor
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Uterine/cervical problems, low wt, chronic illness, previous preterm labor/birth, febrile illness, substance abuse
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fFN
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presence of this between 20-34 weeks shown to be strong indicator of preterm delivery
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Tocolysis
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use of medication to stop labor
delays birth 2-7 days does not improve neonatal outcome but allows time for administration of bethamethasone |
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Pregnancy Induced Hypertension
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preeclampsia/eclampsia
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Preeclampsia
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increase in BP after 20 weeks gestation w/ proteinuria
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Characteristics of preeclampsia
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increased viscosity of blood, hyperreflexia, HA, subcapsular hematoma of liver
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HTN effects on fetus
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SGA, fetal hypoxia, death related to abruption, prematurity
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Mild Preeclampsia
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BP 140/90, proteinuria 1+ to 2+
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S&S of worsening preeclampsia
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increased edema, worsening HA, visual disturbances, decreased urinary output, N&V, bleeding gums, overall not feeling well
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Severe preeclampsia
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BP 180/110 or higher, proteinuria 3+
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S&S of Severe preeclampsia
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HA or visual disturbances, pulmonary edema, epigastric pain, impaired liver fxn, fetal growth restriction
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Eclampsia
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onvulsion or coma occuring before, during or early postpartum
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* What do you administer to prevent seizures of eclampsia?
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magnesium sulfate!
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HELLP syndrome
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hemolysis, elevated liver enzymes, low platelet count
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Rh incompatibility
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Rh+ father and Rh- mother, fetus Rh+
can result in CHF |
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Amniotic Fluid Index
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<5 is a red flag
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Non-Stress Test
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electronic fetal monitor to obtain tracing of FHR, observing accelerations of the FHR w/ movement
REACTIVE IS GOOD |
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Amniocentesis
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used to test biochemical determinations and fetal lung maturity
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Chorionic Villi Sampling
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used to test for DNA abnormalities
|
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*Folic acid deficiency is linked to what?
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Neural Tube Defects
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*Amino Acid Deficits can cause what?
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Mental Retardation and growth restrictions
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*Maternal Wt Gain Distribution
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11lbs-placenta/fetus/amniotic fluid
2lbs-uterus 4lbs-increased blood volume 3lbs-breast tissue 5-10 lbs-maternal stores |
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*kcal increase during pregnancy
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300kcal increase during 2nd and 3rd trimesters only
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Mother's calcium needs
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>19yrs-1000mg/day
<18yrs-1300mg/day |
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Phosphorous RDA during pregnancy
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DOES NOT CHANGE
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RDA for Iron during pregnancy
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27mg/day
|
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Effects of Vit A Deficiency
|
preterm birth, IUGR, low birth weight
|
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Mercury in Fish can cause what?
|
neurotoxic effects of mercury
|
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What do spermicides use?
|
nonoxynol-9
|
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Oral contraceptives can also cause what?
|
decreased menstrual flow, more regularity, decreased formation of ovarian cysts, less cramps, less risk of ovarian and endometrial cancer and ectopics, decrease hirsutism and acne
|
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Depo-provera
|
IM injection of progestin lasts for 3mo
|
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Female Tubal Ligation
|
fallopian tubes are cut
|
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Essure method of permanent sterilization
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no surgery. insert into fallopian tubes under hysteroscopy
after 3 mo the inserts will cause occlusion |
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Clinical Interruption of Pregnancy
|
up to 49 days following first day of LMP
surgical interruption safer in 1st trimester |