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12 Cards in this Set

  • Front
  • Back
Birth Control via contraception

two methods
prevent implantation of fertilized ovum in the endometrium

inhibiting contact of sperm w/mature ovum
Oral Contraceptives

types
Combined oral contraceptives (COCs)
- estrogen plus progestin

Progestin only
- breastfeeding women
- effecacy less tha COCs
- free of CV risks (unlike estrogen)

Long-term injectables or implantables
- progestin only

Drospirinone
Oral contraceptives

PMDD
Premenstrual dysphoric disorder (PMDD) (YAZ only): For treatment of symptoms of PMDD in women who choose to use an oral contraceptive as their method of contraception. The effectiveness of YAZ for PMDD when used for more than 3 menstrual cycles has not been evaluated.
OCs

black box
Smoking: Cigarette smoking increases the risk of serious cardiovascular side effects from oral contraceptives (OCs). This risk increases with age and with heavy smoking (at least 15 cigarettes daily) and is quite marked in women older than 35 years of age. Women who use OCs should not smoke.
OCs

prevention of pregnancy
Because of the positive association between the amount of estrogen and progestin in OCs and the risk of vascular disease and thromboembolism, minimizing exposure to these agents is in keeping with good principles of therapeutics. For any particular combination, prescribe the dosage regimen that contains the least amount of estrogen and progestin compatible with a low failure rate and needs of the individual patient. Start new patients on preparations containing estrogen 35 mcg or less.
OCs

Acne
Acne vulgaris (Ortho Tri-Cyclen and Estrostep only): For the treatment of moderate acne vulgaris in females at least 15 years of age who have no known contraindications to oral contraceptive therapy and who desire contraception, have achieved menarche, and are unresponsive to topical antiacne medications.
OCs

MOA - progestin and estrogen
Estrogen
- prevents development of a dominant
follicle
- does not suppress ovulation

Progestins
- blocks ovulation
- leads to production of thick cervical
mucous
- contributes to involution and atrophy
of the endometrium
OCs

estrogens
ethinyl estradiol

mestranol
OCs

progestins
desogestrel

norgestrel; levonorgestrel

ethynodiol diacetate

norethindrone, norethindrone acetate
and, norethynodrel
OCs

CIs to estrogen
-breast cancer
-recent dvt, pe, stroke, CAD, IHD
-DM w/vascular dz (nephropathy,
retinopathy, neuropathy etc)
-HTN > 160/100
-pregnancy
-surgery w/prolonged immobilization
-structural heart dz (inc risk of VTE)
-eg afib
OCs

What to use if pt has CI
progestin only OCs

depot medroxyprogesterone

intrauterine device
OCs

progestin only products
pills
- 350 µg norethindrone
- Micronor Nor-QD Nora-BE Jolivette,
Camila, Errin
Implants
-etonogestrel (0.12 mg/24h)
-Norplant system
Injection
- medroxyprogesterone (150mg/ml)
- Depo-Provera
IUD
- Progesterone (Progestasert)
- levonorgestrel (Mirena)