Winter 2 Adrenal Hypothalamus Thyroid

Front 1

Corticotropin

Back 1

CRH
Stims pituitary to make ACTH

Front 2

Cortisone

Back 2

Weak short acting cortisol

Front 3

Dexamethasone

Back 3

Strongest long acting cortisol
Anti inflammatory

Test: if no suppression of cortisol then cushing syndrome

Front 4

Hydrocortisone

Back 4

Weak short acting

Front 5

Methylprednisolone

Back 5

Strong short acting

Front 6

Prednisone

Back 6

Strong short acting

Front 7

Fludrocortisone

Back 7

Replaces Aldosterone
Ind: CSW, Addisons, Post. hypotension

Test: If aldo not suppressed then Conn syndrome (adrenal adenoma)

Front 8

Mifepristone

Back 8

Anticortisol/Antiprogestin

Front 9

Ketoconazole

Back 9

Inhibit Adrenal in cushing

SFX:
Hepatitis
Increased liver enzymes

Front 10

Spironolactone

Back 10

Blocks Aldo & Testosterone

SFX:
Hyperkalemia
Gynecomastia
Metabolic Acidosis
Teratogen

Front 11

Aminoglutethimide

Back 11

Block Cholesterol to Pregnenolone
Decreases all steroid hormones
Ind: Breast cancer & adrenal malignancy

Front 12

Mitotane

Back 12

Adrenal cortex suppressor
Lowers Cortisol
Ind: Adrenocortical Carcinoma

Front 13

Cosyntropin

Back 13

ACTH receptor agonist

Test: if no cortisol spike then primary adrenal insufficiency

Front 14

Somatropin

Back 14

Surface JAK/STAT Cytokine receptor uses 2 GH

Front 15

Mecasermin

Back 15

IGF1

needed for GH to work

SFX:
Hypoglycemia

Front 16

Octreotide

Back 16

45x stronger version of Somatostatin
Inhibit GH release

SFX:
Gallstone
Biliary sludge

Front 17

Pegvisomant

Back 17

GH antagonist

Front 18

Bromocriptine

Back 18

D2 agonist, inhibit prolactin secretion

Front 19

Carbergoline

Back 19

D2 agonist, inhibit prolactin secretion

Front 20

Follitropin

Back 20

FSH receptor agonist

Front 21

Lutropin

Back 21

LH receptor agonist

Ind: Women w/ hypogonadotropic hypogonadism give LH and FSH

Front 22

Menotropin

Back 22

LH receptor agonist

Ind: Women w/ hypogonadotropic hypogonadism give LH and FSH

Front 23

Choriogonadotropin

Back 23

hCG

Front 24

Gonadorelin

Back 24

GnRH receptor agonist

Ind: infertility
to suppress GnRH release

Front 25

Goserelin

Back 25

GnRH receptor agonist

Front 26

Histrelin

Back 26

GnRH receptor agonist

Front 27

Leuprolide

Back 27

GnRH receptor antagonist
Prevent LH surge in ovarian hyperstim

Front 28

Abarelix

Back 28

GnRH receptor antagonist
Prevent LH surge in ovarian hyperstim

Front 29

Ganirelix

Back 29

GnRH receptor antagonist
Prevent LH surge in ovarian hyperstim

Front 30

Cetrorelix

Back 30

GnRH receptor antagonist
Prevent LH surge in ovarian hyperstim

Front 31

Levothyroxine

Back 31

T4 once daily

Front 32

Liothyronine

Back 32

T3

Front 33

Liotrix

Back 33

T4:T3 mix

Front 34

Thyrotropin alpha

Back 34

TSH

Test: Releases thyroglobulin to check levels for cancer

Front 35

Propylthiouracil

Back 35

Inhibit Thyroid peroxidase rxn
Blocks T4 to T3 conversion peripherally
Slow onset

SFX:
Agranulocytosis
Hepatotoxicity

Front 36

Methimazole

Back 36

Inhibit Thyroid peroxidase rxn
Blocks T4 to T3 conversion peripherally
Slow onset

SFX:
Agranulocytosis

Front 37

Potassium Iodide

Back 37

To prevent uptake of radioactive iodide during imaging

Front 38

Perchlorate

Back 38

Block iodide uptake by competitive inhibition

Front 39

Thiocyanate

Back 39

Block iodide uptake by competitive inhibition

Front 40

Radioactive iodide

Back 40

Destroys thyroid by beta rays

Front 41

Propranolol

Back 41

Beta antagonist

SFX:
Depression
Claudication
Bronchospasm
CHF
Masks hypoglycemia in diabetes