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24 Cards in this Set
- Front
- Back
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Neutrophilia indicates what?
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bacterial infection
AKA Left Shift |
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Eosinophilia indicates what?
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Type 1 Hypersensitivity
Parasites |
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Monocytosis indicates what?
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TB
Inflammatory Bowel Diseases |
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Lymphocytosis indicates what?
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viral diseases
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Describe Infectious Mononucleosis (IM)
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viral disease that causes lymphocytosis
Epstein-Barr Virus (EBV) Cytomegalovirus (CMV) Cytotoxic (CD8) cells respond against B-cells |
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Describe Actue Lymphoblastic Leukemia (ALL)
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precursor to CA
Lymphocytes are positive for terminal deoxytransferase (TdT) child with mediastinal lymphadenopathy |
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Describe Chronic Lymphocytic Leukemia (CLL)
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Age = 60
Labs: smudge cells in blood |
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Describe Small Lymphocytic Lymphoma (SLL)
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Age = 60
Labs: smudge cells in blood (if metastasis from lymph) |
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Describe Follicular Lymphoma
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t(14;18)
bcl-2 |
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Describe Hariy Cell Leukemia
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varient of CLL
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Describe Diffuse Large B-Cell Lymphoma
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rapid progression of Follicular Lymphoma
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Describe Burkitt Lymphoma
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AKA small noncleaved lymphoma
"starry-sky" macrophages t(8;14) c-myc mandible or maxilla EBV abdomen/pelvic lymphadenopathy |
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Describe Mantle Cell Lymphoma (MCL)
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t(11;14)
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Describe Marginal Zone Lymphoma (MALToma)
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GI tract
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Describe Multiple Myeloma
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elderly
low back pain IgG or IgA M-spike Rouleaux configuration hypercalcemia pancytopenia |
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Describe Waldenstrom Macroglobinemia
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AKA Lymphoplasmacytic Lymphoma
IgM M-spike hyperviscocity Raynaud's |
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Describe Mycosis Fungoides (MF)
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skin/lymph T-cell (CD4) CA
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Describe Sezary Syndrome (SS)
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blood T-cell (CD4) CA
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Describe Adult T-Cell Leukemia/Lymphoma (ATLL)
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HTLV-1 infection
hypercalcemia Japan/Caribbean |
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Describe Hodgkin Disease (HD)
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Reed-Sternberg (RS) cells - "owl-eye" (do not confuse with CMV)
CD15 & CD30 Most common subtype is Nodular Sclerosis (Lacunar Cells) Tx: stage 1 & 2 = radiation stage 3 & 4 = chemotherapy |
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Describe Acute Myelogenous Leukemia (AML)
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large WBC with granules in cytoplasm
MPO (myeloperoxidase) (+) Auer rods (M3 subtype) increased risk of DIC t(15;17) |
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Describe Chronic Myelogenous Leukemia (CML)
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splenomegaly
t(9;22) [Philadelphia chromosome] ↓ Leukocyte Alkaline Phosphatase (LAP) [if ↑, points to infection] |
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Describe Polycythemia vera
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↓ fat cells in marrow
↓ EPO (erythropoietin) splenomegaly intense pruritus (basophils release histamine) |
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Describe Myelofibrosis
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teardrop RBCs
scarred marrow "dry tap" |
