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10 Cards in this Set

  • Front
  • Back
Parathyroid Hormone (PTH)
clinical use?
clinical use- diagnosis of

pseudohypoparathyroidism
osteoporosis
Calcitonin treatment of?
Paget’s disease, acute hypercalcemia, osteoporosis (nasal spray), osteolytic bone metastases
Vitamin D treatment of?
hypocalcemia
hypoparathyroidism
rickets
osteomalacia
kidney disease (2° hyperparathyroidism)
Biphosphonates (etidronate, alendronate, pamidronate, ibandronate, zoledronic acid)

capabilities?
They have strong affinity for bone.
They are capable of chelating Ca
Direct inhibition of bone reabsorption
Remain in the bone matrix until the bone is remodeled and then are released.
They have strong affinity for bone.
They are capable of chelating Ca
Direct inhibition of bone reabsorption
Remain in the bone matrix until the bone is remodeled and then are released.

uses?
Paget’s disease
osteoporosis
Estrogens use?
Estrogens — decrease osteoclastic activity
Selective Estrogen Receptor Modulators (SERMS) — Raloxifene
MOA?
Mechanism — decreases bone resorption (estrogen agonist on bone)
EDTA
uses?
Uses — hypercalcemia (chelating agent)
Glucocorticoids uses?
Uses – hypercalcemia (increases Ca++ excretion)
Cinacalcet (Sensipar) use for?
2° Hyperparathroidism (kidney disease)