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8 Cards in this Set

  • Front
  • Back

Acute Stress Response is a reaction to threatening stimuli, which includes?

Avoidance behaviour


Increased Vigilance and Arousal




Activation of Sympathetic NS




Release of Aderanline from Adrenal Medulla (fastest and first hormonal response)




Release of cortisol from Adrenal Cortex

Cortisol is a steroid hormone produced by the Adrenal Gland, what are it's functions?

Released in response to more intense or sustained stress




Mobilizes energy reserves and suppresses the immune system




Dysregulation/excessive release thought to contribute to anxiety disorders

Hypothalamus directly controls the stress response via?

activation of Sympathetic NS & hormone release

What regulates the HPA axis?




(hypothalamic-pituitary-adrenal axis)

Amygdala & hippocampus

Amygdala & hippocampus

Amygdala activates stress via?

central nucleus of amygdala




(affects hypothalamus etc)

Studies in animals and humans show chronic stress causes degeneration of the hippocampus, this is possibly due to?

Over-activation of neurons by glucocorticoids (cortisol)




Causing excitotoxic cell death

Can hippocampal nuerons regenerate?

Yes, neural stem cells within the hippocampus can produce new neurons. However is inhibited by chronic stress

watch lecture on GABA receptors

watch lecture on GABA receptors