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25 Cards in this Set
- Front
- Back
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antigen
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what antibodies recognize and bind to
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antibody
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glycoprotein called immunoglobulin (Ig); binds antigen; produced by B cells
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active immunity
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individual plays role in responding to antigen (immunizations)
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passive immunity
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transfer of antibody to recipient that has never responded to antigen
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innate immunity
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protection that exists before infection occurs; not specific
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adaptive immunity
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protection stimulated by exposure ot infectious agent
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phagocytosis
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phagocytes of immune system engulf large particles like microbes - leads to phagosome, fuses with lysosomes to digest ingested material
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neutrophils
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phagocyte, most abundant WBC, also called PMN, recruited to sites of inflammation, kill microbes
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macrophages
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phagocyte, tissue based, phagocytic, derived from blook monocytes, kill microbes, secrete and respond to cytokines
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dendritic cells
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phagocyte, thin projections, phagocytose microbes in tissue travel to lymph nodes, show antigens to lymphocytes, initiates adaptive immune response
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humoral immunity
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immunity mediated by antibodies or complement or both
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cellular immunity
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immunity mediated by cells
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lymphocytes
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found in blood, lymphoid tissues, and other organs, T and B lymphocytes found in large numbers in lymph nodes nad proliferate there in infections
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NK (Natural Killer) cells
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lymphocytes of innate immunity, found in blood and throughout body, act when they detect stressed cells
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T cells
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lymphocytes of adaptive immunity, in blood and lymph nodes, mediate cell-mediated immunity and help B cells produce antibody, act when they bind antigen
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B cells
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lymphocytes of adaptive immunity found in lymph nodes, make antibody, humoral immunity, act when they bind antigen
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naive lymphocytes
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T or B lymphocytes, not NK cells bc dont bind antigen, have never encountered antigen they can bind to, live for few weeks
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effector lymphocytes
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T or B lymphocytes, encountered antigen they bind, programmed to perform their function immediately, only live few days
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memory lymphocytes
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T or B lymphocytes, encountered antigen can bind to, live for years and reqctivate quickly when encounter antigen
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Bone marrow/ thymus
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generative/primary central lymphoid organs; B cells born/mature into naive cells in BM; T cells born in BM mature in thymus
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chemokines
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large family of structurally similar, low molecular weight pro stimulate and regulate leukocyte migration
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primary lymphoid organs
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bone marrow
thymus |
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secondary lymphoid organs
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spleen
lymph nodes mucosal/cutaneous lymphoid tissues |
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follicles of l nodes
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B cells
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paracortex of l nodes
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T cells
dendritic cells |
